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Bimal Koirala
Bimal Koirala
在 merck.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
A naturally inspired antibiotic to target multidrug-resistant pathogens
Z Wang, B Koirala, Y Hernandez, M Zimmerman, S Park, DS Perlin, ...
Nature 601 (7894), 606-611, 2022
1502022
Bioinformatic prospecting and synthesis of a bifunctional lipopeptide antibiotic that evades resistance
Z Wang, B Koirala, Y Hernandez, M Zimmerman, SF Brady
Science 376 (6596), 991-996, 2022
702022
Structure–Activity Relationships of the Competence Stimulating Peptides (CSPs) in Streptococcus pneumoniae Reveal Motifs Critical for Intra-group and Cross …
Y Yang, B Koirala, LA Sanchez, NR Phillips, SR Hamry, Y Tal-Gan
ACS chemical biology 12 (4), 1141-1151, 2017
552017
Synthetic-bioinformatic natural product antibiotics with diverse modes of action
J Chu, B Koirala, N Forelli, X Vila-Farres, MA Ternei, T Ali, DA Colosimo, ...
Journal of the American Chemical Society 142 (33), 14158-14168, 2020
462020
Identification of structurally diverse menaquinone-binding antibiotics with in vivo activity against multidrug-resistant pathogens
L Li, B Koirala, Y Hernandez, LW MacIntyre, MA Ternei, R Russo, ...
Nature microbiology 7 (1), 120-131, 2022
372022
Development of a Dominant Negative Competence‐Stimulating Peptide (dnCSP) that Attenuates Streptococcus pneumoniae Infectivity in a Mouse Model of Acute …
B Koirala, J Lin, GW Lau, Y Tal‐Gan
ChemBioChem 19 (22), 2380-2386, 2018
272018
Biosynthetic Interrogation of Soil Metagenomes Reveals Metamarin, an Uncommon Cyclomarin Congener with Activity against Mycobacterium tuberculosis
L Li, LW MacIntyre, T Ali, R Russo, B Koirala, Y Hernandez, SF Brady
Journal of natural products 84 (4), 1056-1066, 2021
232021
Metabolites with SARS-CoV-2 inhibitory activity identified from human microbiome commensals
FJ Piscotta, HH Hoffmann, YJ Choi, GI Small, AW Ashbrook, B Koirala, ...
Msphere 6 (6), e00711-21, 2021
162021
Unveiling the Importance of Amide Protons in CSP:ComD Interactions in Streptococcus pneumoniae
B Koirala, NR Phillips, Y Tal-Gan
ACS Medicinal Chemistry Letters 10 (6), 880-886, 2019
132019
Defining the hydrophobic interactions that drive competence stimulating peptide (CSP)-ComD binding in Streptococcus pneumoniae
B Koirala, RA Hillman, EK Tiwold, MA Bertucci, Y Tal-Gan
Beilstein journal of organic chemistry 14 (1), 1769-1777, 2018
122018
Development of Streptococcus pneumoniae Pan‐Group Quorum‐Sensing Modulators
B Koirala, Y Tal‐Gan
ChemBioChem 21 (3), 340-345, 2020
112020
Harnessing Multiple, Nonproteogenic Substitutions to Optimize CSP:ComD Hydrophobic Interactions in Group 1 Streptococcus pneumoniae
TA Milly, ER Engler, KS Chichura, AR Buttner, B Koirala, Y Tal‐Gan, ...
ChemBioChem 22 (11), 1940-1947, 2021
102021
Discovery of Paenibacillaceae family Gram-negative-active cationic lipopeptide antibiotics using evolution-guided chemical synthesis
Z Wang, B Koirala, Y Hernandez, SF Brady
Organic letters 24 (27), 4943-4948, 2022
82022
Synthesis and evaluation of dual-action kanglemycin-fluoroquinolone hybrid antibiotics
J Peek, B Koirala, SF Brady
Bioorganic & medicinal chemistry letters 57, 128484, 2022
72022
Metabolites with SARS-CoV-2 Inhibitory Activity Identified from Human Microbiome Commensals. mSphere. 2021: e0071121
FJ Piscotta, HH Hoffmann, YJ Choi, GI Small, AW Ashbrook, B Koirala, ...
Epub 2021/12/02. https://doi. org/10.1128/mSphere. 00711-21 PMID: 34851166, 0
5
Cinnamosyn, a Cinnamoylated Synthetic-Bioinformatic Natural Product with Cytotoxic Activity
LW MacIntyre, B Koirala, A Rosenzweig, A Morales-Amador, SF Brady
Organic Letters, 2024
12024
Front Cover: Development of Streptococcus pneumoniae Pan‐Group Quorum‐Sensing Modulators (ChemBioChem 3/2020)
B Koirala, Y Tal‐Gan
ChemBioChem 21 (3), 279-279, 2020
2020
Development of Peptide-Based Probes to Target Quorum Sensing in Streptococcus pneumoniae
B Koirala
2019
Effects of multiple amino acid mutations of a key quorum sensing peptide, CSP-1
K Chichura, B Koirala, Y Tal-Gana, M Bertucci
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
Remodeling the hydrophobic face of CSP-1, a peptide autoinducer for quorum sensing in Streptococcus pneumoniae
R Hillman, E Tiwold, B Koirala, Y Tal-Gan, M Bertucci
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
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