M2 macrophage-derived exosomes promote cell migration and invasion in colon cancer J Lan, LI Sun, F Xu, L Liu, F Hu, D Song, Z Hou, W Wu, X Luo, J Wang, ... Cancer research 79 (1), 146-158, 2019 | 534 | 2019 |
Lactate is a natural suppressor of RLR signaling by targeting MAVS W Zhang, G Wang, ZG Xu, H Tu, F Hu, J Dai, Y Chang, Y Chen, Y Lu, ... Cell 178 (1), 176-189. e15, 2019 | 434 | 2019 |
The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance F Han, CF Li, Z Cai, X Zhang, G Jin, WN Zhang, C Xu, CY Wang, J Morrow, ... Nature communications 9 (1), 4728, 2018 | 159 | 2018 |
SETDB1-mediated methylation of Akt promotes its K63-linked ubiquitination and activation leading to tumorigenesis G Wang, J Long, Y Gao, W Zhang, F Han, C Xu, L Sun, SC Yang, J Lan, ... Nature cell biology 21 (2), 214-225, 2019 | 148 | 2019 |
IL-6 regulates autophagy and chemotherapy resistance by promoting BECN1 phosphorylation F Hu, D Song, Y Yan, C Huang, C Shen, J Lan, Y Chen, A Liu, Q Wu, ... Nature communications 12 (1), 3651, 2021 | 121 | 2021 |
Brg-1 targeting of novel miR550a-5p/RNF43/Wnt signaling axis regulates colorectal cancer metastasis G Wang, Y Fu, X Yang, X Luo, J Wang, J Gong, J Hu Oncogene 35 (5), 651-661, 2016 | 72 | 2016 |
Inhibition of SIRT2 limits tumour angiogenesis via inactivation of the STAT3/VEGFA signalling pathway F Hu, X Sun, G Li, Q Wu, Y Chen, X Yang, X Luo, J Hu, G Wang Cell death & disease 10 (1), 9, 2018 | 71 | 2018 |
PIK3R3 induces epithelial-to-mesenchymal transition and promotes metastasis in colorectal cancer G Wang, X Yang, C Li, X Cao, X Luo, J Hu Molecular cancer therapeutics 13 (7), 1837-1847, 2014 | 71 | 2014 |
Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway G Wang, Y Fu, F Hu, J Lan, F Xu, X Yang, X Luo, J Wang, J Hu Cell Death & Disease 8 (2), e2607-e2607, 2017 | 49 | 2017 |
p55PIK-PI3K stimulates angiogenesis in colorectal cancer cell by activating NF-κB pathway G Wang, C Chen, R Yang, X Cao, S Lai, X Luo, Y Feng, X Xia, J Gong, ... Angiogenesis 16, 561-573, 2013 | 48 | 2013 |
KDM4B facilitates colorectal cancer growth and glucose metabolism by stimulating TRAF6-mediated AKT activation H Li, J Lan, G Wang, K Guo, C Han, X Li, J Hu, Z Cao, X Luo Journal of Experimental & Clinical Cancer Research 39, 1-13, 2020 | 47 | 2020 |
PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis X Yang, Y Fu, F Hu, X Luo, J Hu, G Wang Experimental & molecular medicine 50 (1), e431-e431, 2018 | 43 | 2018 |
Altered p53 regulation of miR-148b and p55PIK contributes to tumor progression in colorectal cancer G Wang, X Cao, S Lai, X Luo, Y Feng, J Wu, Q Ning, X Xia, J Wang, ... Oncogene 34 (7), 912-921, 2015 | 41 | 2015 |
NSD2 promotes tumor angiogenesis through methylating and activating STAT3 protein D Song, J Lan, Y Chen, A Liu, Q Wu, C Zhao, Y Feng, J Wang, X Luo, ... Oncogene 40 (16), 2952-2967, 2021 | 39 | 2021 |
PI3K stimulates DNA synthesis and cell-cycle progression via its p55PIK regulatory subunit interaction with PCNA G Wang, X Cao, S Lai, X Luo, Y Feng, X Xia, PM Yen, J Gong, J Hu Molecular cancer therapeutics 12 (10), 2100-2109, 2013 | 36 | 2013 |
BRG1 promotes VEGF-A expression and angiogenesis in human colorectal cancer cells J Lan, H Li, X Luo, J Hu, G Wang Experimental Cell Research 360 (2), 236-242, 2017 | 34 | 2017 |
Blocking p55PIK signaling inhibits proliferation and induces differentiation of leukemia cells G Wang, Y Deng, X Cao, S Lai, Y Tong, X Luo, Y Feng, X Xia, J Gong, ... Cell Death & Differentiation 19 (11), 1870-1879, 2012 | 32 | 2012 |
Blocking histone methyltransferase SETDB1 inhibits tumorigenesis and enhances cetuximab sensitivity in colorectal cancer Z Hou, L Sun, F Xu, F Hu, J Lan, D Song, Y Feng, J Wang, X Luo, J Hu, ... Cancer letters 487, 63-73, 2020 | 28 | 2020 |
EZH2-triggered methylation of SMAD3 promotes its activation and tumor metastasis C Huang, F Hu, D Song, X Sun, A Liu, Q Wu, X She, Y Chen, L Chen, ... The Journal of Clinical Investigation 132 (5), 2022 | 26 | 2022 |
Intratumoral microbiota composition regulates chemoimmunotherapy response in esophageal squamous cell carcinoma H Wu, X Leng, Q Liu, T Mao, T Jiang, Y Liu, F Li, C Cao, J Fan, L Chen, ... Cancer Research 83 (18), 3131-3144, 2023 | 23 | 2023 |