| A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation HP Shih, JL Kopp, M Sandhu, CL Dubois, PA Seymour, A Grapin-Botton, ... Development 139 (14), 2488-2499, 2012 | 268 | 2012 |
| Variable G protein determinants of GPCR coupling selectivity N Okashah, Q Wan, S Ghosh, M Sandhu, A Inoue, N Vaidehi, NA Lambert Proceedings of the National Academy of Sciences 116 (24), 12054-12059, 2019 | 149 | 2019 |
| C-NHEJ without indels is robust and requires synergistic function of distinct XLF domains R Bhargava, M Sandhu, S Muk, G Lee, N Vaidehi, JM Stark Nature communications 9 (1), 2484, 2018 | 88 | 2018 |
| Conformational plasticity of the intracellular cavity of GPCR− G-protein complexes leads to G-protein promiscuity and selectivity M Sandhu, AM Touma, M Dysthe, F Sadler, S Sivaramakrishnan, ... Proceedings of the National Academy of Sciences 116 (24), 11956-11965, 2019 | 75 | 2019 |
| Structural elements in the Gαs and Gαq C termini that mediate selective G protein-coupled receptor (GPCR) signaling A Semack, M Sandhu, RU Malik, N Vaidehi, S Sivaramakrishnan Journal of Biological Chemistry 291 (34), 17929-17940, 2016 | 54 | 2016 |
| The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk neuroblastoma M Pan, WC Wright, RH Chapple, A Zubair, M Sandhu, JE Batchelder, ... Nature communications 12 (1), 6468, 2021 | 51 | 2021 |
| The role of HER2 and HER3 in HER2-amplified cancers beyond breast cancers A Majumder, M Sandhu, D Banerji, V Steri, A Olshen, MM Moasser Scientific reports 11 (1), 9091, 2021 | 34 | 2021 |
| Targeting HER3 by interfering with its Sec61-mediated cotranslational insertion into the endoplasmic reticulum A Ruiz-Saenz, M Sandhu, Y Carrasco, RL Maglathlin, J Taunton, ... Oncogene 34 (41), 5288-5294, 2015 | 31 | 2015 |
| Dynamic spatiotemporal determinants modulate GPCR: G protein coupling selectivity and promiscuity M Sandhu, A Cho, N Ma, E Mukhaleva, Y Namkung, S Lee, S Ghosh, ... Nature Communications 13 (1), 7428, 2022 | 28 | 2022 |
| Machine learning for prioritization of thermostabilizing mutations for G-protein coupled receptors S Muk, S Ghosh, S Achuthan, X Chen, XJ Yao, M Sandhu, MC Griffor, ... Biophysical Journal 117 (11), 2228-2239, 2019 | 17 | 2019 |
| Distinct structural mechanisms determine substrate affinity and kinase activity of protein kinase Cα S Lee, T Devamani, HD Song, M Sandhu, A Larsen, R Sommese, A Jain, ... Journal of Biological Chemistry 292 (39), 16300-16309, 2017 | 15 | 2017 |
| The PDE10A inhibitor TAK-063 reverses sound-evoked EEG abnormalities in a mouse model of fragile X syndrome CR Jonak, MS Sandhu, SA Assad, JA Barbosa, M Makhija, DK Binder Neurotherapeutics 18 (2), 1175-1187, 2021 | 14 | 2021 |
| Bitopic inhibition of ATP and substrate binding in Ser/Thr kinases through a conserved allosteric mechanism N Ma, LG Lippert, T Devamani, B Levy, S Lee, M Sandhu, N Vaidehi, ... Biochemistry 57 (45), 6387-6390, 2018 | 12 | 2018 |
| Baclofen-associated neurophysiologic target engagement across species in fragile X syndrome CR Jonak, EV Pedapati, LM Schmitt, SA Assad, MS Sandhu, L DeStefano, ... Journal of Neurodevelopmental Disorders 14 (1), 52, 2022 | 11 | 2022 |
| How Does the Proliferating Cell Nuclear Antigen Modulate Binding Specificity to Multiple Partner Proteins? H Li, M Sandhu, LH Malkas, RJ Hickey, N Vaidehi Journal of Chemical Information and Modeling 57 (12), 3011-3021, 2017 | 10 | 2017 |
| Molecular determinants of ligand efficacy and potency in GPCR signaling FM Heydenreich, M Marti-Solano, M Sandhu, BK Kobilka, M Bouvier, ... Science 382 (6677), eadh1859, 2023 | 6 | 2023 |
| Recent breakthroughs in computational structural biology harnessing the power of sequences and structures B Mészáros, E Park, D Malinverni, BI Sejdiu, K Immadisetty, M Sandhu, ... Current Opinion in Structural Biology 80, 102608, 2023 | 3 | 2023 |
| Dissecting the allosteric networks governing agonist efficacy and potency in G protein-coupled receptors FM Heydenreich, M Marti-Solano, M Sandhu, BK Kobilka, M Bouvier, ... bioRxiv, 2021.09. 14.460253, 2021 | 3 | 2021 |
| Phenotypic analysis of multielectrode array EEG biomarkers in developing and adult male Fmr1 KO mice CR Jonak, SA Assad, TA Garcia, MS Sandhu, JA Rumschlag, KA Razak, ... Neurobiology of Disease 195, 106496, 2024 | 1 | 2024 |
| Computational approaches to study biomolecular recognition by G proteins and G protein coupled receptors M Sandhu City of Hope's Irell & Manella Graduate School of Biomedical Sciences, 2020 | | 2020 |
