Nicotinamide phosphoribosyltransferase inhibitors selectively induce apoptosis of AML stem cells by disrupting lipid homeostasis A Subedi, Q Liu, DM Ayyathan, D Sharon, S Cathelin, M Hosseini, C Xu, ... Cell Stem Cell 28 (10), 1851-1867. e8, 2021 | 62 | 2021 |
Globular adiponectin causes tolerance to LPS-induced TNF-α expression via autophagy induction in RAW 264.7 macrophages: involvement of SIRT1/FoxO3A axis N Tilija Pun, A Subedi, MJ Kim, PH Park PloS one 10 (5), e0124636, 2015 | 55 | 2015 |
Antioxidant and antibacterial activity of methanolic extract of Machilus odoratissima A Subedi, MP Amatya, TM Shrestha, SK Mishra, BM Pokhrel Kathmandu University Journal of Science, engineering and technology 8 (1), 73-80, 2012 | 52 | 2012 |
Autocrine and paracrine modulation of microRNA-155 expression by globular adiponectin in RAW 264.7 macrophages: involvement of MAPK/NF-κB pathway A Subedi, PH Park Cytokine 64 (3), 638-641, 2013 | 47 | 2013 |
Globular adiponectin inhibits ethanol-induced apoptosis in HepG2 cells through heme oxygenase-1 induction S Nepal, MJ Kim, A Subedi, ES Lee, CS Yong, JA Kim, WK Kang, ... Biochemical pharmacology 84 (7), 974-983, 2012 | 47 | 2012 |
High-throughput screening identifies artesunate as selective inhibitor of cancer stemness: involvement of mitochondrial metabolism A Subedi, Y Futamura, M Nishi, A Ryo, N Watanabe, H Osada Biochemical and biophysical research communications 477 (4), 737-742, 2016 | 31 | 2016 |
Combination of enasidenib and venetoclax shows superior anti-leukemic activity against IDH2 mutated AML in patient-derived xenograft models S Cathelin, D Sharon, A Subedi, D Cojocari, DC Phillips, JD Leverson, ... Blood, The Journal of the American Society of Hematology 132 (Supplement 1 …, 2018 | 29 | 2018 |
Globular adiponectin modulates expression of programmed cell death 4 and miR-21 in RAW 264.7 macrophages through the MAPK/NF-κB pathway A Subedi, MJ Kim, S Nepal, ES Lee, JA Kim, DH Sohn, K Song, SH Lee, ... FEBS letters 587 (10), 1556-1561, 2013 | 19 | 2013 |
Discovery of novel selenium derivatives as Pin1 inhibitors by high-throughput screening A Subedi, T Shimizu, A Ryo, E Sanada, N Watanabe, H Osada Biochemical and Biophysical Research Communications 474 (3), 528-533, 2016 | 18 | 2016 |
Enasidenib-induced differentiation promotes sensitivity to venetoclax in IDH2-mutated acute myeloid leukemia S Cathelin, D Sharon, A Subedi, D Cojocari, DC Phillips, JD Leverson, ... Leukemia 36 (3), 869-872, 2022 | 12 | 2022 |
A novel inhibitor of tumorspheres reveals the activation of the serine biosynthetic pathway upon mitochondrial inhibition A Subedi, M Muroi, Y Futamura, T Kawamura, H Aono, M Nishi, A Ryo, ... FEBS letters 593 (8), 763-776, 2019 | 5 | 2019 |
Targeting mitochondrial translation overcomes venetoclax resistance in acute myeloid leukemia (AML) through activation of the integrated stress response D Sharon, S Cathelin, A Subedi, R Williams, M Benicio, T Ketela, ... Blood 130, 297, 2017 | 2 | 2017 |
Nicotinamide Phosphoribosyltransferase Inhibitors Induce Apoptosis of AML Stem Cells through Dysregulation of Lipid Metabolism A Subedi, Q Liu, D Sharon, S Cathelin, GD Bader, C Xu, V Voisin, ... Blood 136, 25-26, 2020 | 1 | 2020 |
Antimotility Effect of Machiluss odoratissima & Sonchus wightianus from Nepal A Subedi, D Khakural, S Amatya, TM Shrestha, MP Amatya | 1 | 2010 |
TET2 Deficiency Increases the Competitive Advantage of Hematopoietic Stem Cells through Upregulation of Thrombopoietin Receptor Signaling S Chan, Y Yang, S Cathelin, A Liu, A Subedi, A Maher, M Hosseini, ... | | 2024 |
The AI-powered KisoSeek™ platform identifies functional anti-TROP2 heavy-chain antibodies with potent anti-cancer activity SE Cousineau, A Subedi, R Wargachuk, J The, X Wang, W Hou, A Nair, ... Cancer Research 84 (6_Supplement), 1869-1869, 2024 | | 2024 |
Functional characterization of KJ-103, a novel therapeutic anti-TROP2 heavy chain-only antibody S Yao, H Zahreddine, A Subedi, L Gong, A Nair, A Zhou, T Cheng, ... Cancer Research 83 (7_Supplement), 2931-2931, 2023 | | 2023 |
Metformin Treatment Abrogates the Competitive Advantage of Dnmt3a R878H HSPCs By Enhancing DNA Methylation Activity M Hosseini, S Cathelin, A Liu, Y Yang, A Subedi, D Manikoth Ayyathan, ... Blood 140 (Supplement 1), 977-978, 2022 | | 2022 |
A Novel Role for PLK1 in Leukemia Stem Cell Function in Acute Myeloid Leukemia Q Liu, A Murison, AGX Zeng, C Xu, V Voisin, F Yeung, A Subedi, ... Blood 140 (Supplement 1), 5920-5921, 2022 | | 2022 |
Thrombopoietin Receptor Signaling Promotes the Competitive Advantage of TET2-Mutated Hematopoietic Stem and Progenitor Cells in Clonal Hematopoiesis Y Yang, A Subedi, SM Chan Blood 140 (Supplement 1), 981-982, 2022 | | 2022 |