Antitumor antibiotics: Bleomycin, enediynes, and mitomycin U Galm, MH Hager, SG Van Lanen, J Ju, JS Thorson, B Shen Chemical Reviews 105 (2), 739-758, 2005 | 650 | 2005 |
Nicotinic receptor binding site probed with unnatural amino acid incorporation in intact cells MW Nowak, PC Kearney, JR Sampson, ME Saks, CG Labarca, ... Science 268 (5209), 439-439, 1995 | 448 | 1995 |
A genomics-guided approach for discovering and expressing cryptic metabolic pathways E Zazopoulos, K Huang, A Staffa, W Liu, BO Bachmann, K Nonaka, ... Nature Biotechnology 21 (2), 187-190, 2003 | 409 | 2003 |
A comprehensive review of glycosylated bacterial natural products SI Elshahawi, KA Shaaban, MK Kharel, JS Thorson Chemical Society Reviews 44 (21), 7591-7697, 2015 | 394 | 2015 |
The calicheamicin gene cluster and its iterative type I enediyne PKS J Ahlert, E Shepard, N Lomovskaya, E Zazopoulos, A Staffa, ... Science 297 (5584), 1173-1176, 2002 | 374 | 2002 |
Structure, activity, synthesis and biosynthesis of aryl-C-glycosides T Bililign, BR Griffith, JS Thorson Natural Product Reports 22 (6), 742-760, 2005 | 367 | 2005 |
Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria H Liu, JS Thorson Annual Reviews in Microbiology 48 (1), 223-256, 1994 | 357 | 1994 |
Exploiting the reversibility of natural product glycosyltransferase-catalyzed reactions C Zhang, BR Griffith, Q Fu, C Albermann, X Fu, IK Lee, L Li, JS Thorson Science 313 (5791), 1291-1294, 2006 | 325 | 2006 |
Expanding the promiscuity of a natural-product glycosyltransferase by directed evolution GJ Williams, C Zhang, JS Thorson Nature Chemical Biology 3 (10), 657-662, 2007 | 313 | 2007 |
Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization JM Langenhan, NR Peters, IA Guzei, FM Hoffmann, JS Thorson Proceedings of the National Academy of Sciences 102 (35), 12305-12310, 2005 | 294 | 2005 |
Antibiotic optimization via in vitro glycorandomization X Fu, C Albermann, J Jiang, J Liao, C Zhang, JS Thorson Nature Biotechnology 21 (12), 1467-1469, 2003 | 274 | 2003 |
Enzymatic methods for glyco (diversification/randomization) of drugs and small molecules RW Gantt, P Peltier-Pain, JS Thorson Natural Product Reports 28 (11), 1811-1853, 2011 | 269 | 2011 |
Nature's carbohydrate chemists: The enzymatic glycosylation of bioactive bacterial metabolites JS Thorson, TJ Hosted Jr, J Jiang, JB Biggins, J Ahlert Current Organic Chemistry 5 (2), 139-167, 2001 | 221 | 2001 |
Understanding and exploiting nature's chemical arsenal: The past, present and future of calicheamicin research JS Thorson, EL Sievers, J Ahlert, E Shepard, RE Whitwam, KC Onwueme, ... Current Pharmaceutical Design 6 (18), 1841-1879, 2000 | 213 | 2000 |
‘Sweetening’natural products via glycorandomization BR Griffith, JM Langenhan, JS Thorson Current Opinion in Biotechnology 16 (6), 622-630, 2005 | 189 | 2005 |
Enzymatic tools for engineering natural product glycosylation S Blanchard, JS Thorson Current Opinion in Chemical Biology 10 (3), 263-271, 2006 | 185 | 2006 |
Incorporation of glucose analogs by GtfE and GtfD from the vancomycin biosynthetic pathway to generate variant glycopeptides HC Losey, J Jiang, JB Biggins, M Oberthür, XY Ye, SD Dong, D Kahne, ... Chemistry & Biology 9 (12), 1305-1314, 2002 | 181 | 2002 |
Neoglycorandomization and chemoenzymatic glycorandomization: Two complementary tools for natural product diversification JM Langenhan, BR Griffith, JS Thorson Journal of Natural Products 68 (11), 1696-1711, 2005 | 178 | 2005 |
Glycosyltransferase structural biology and its role in the design of catalysts for glycosylation A Chang, S Singh, GN Phillips Jr, JS Thorson Current Opinion in Biotechnology 22 (6), 800-808, 2011 | 175 | 2011 |
Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization WA Barton, J Lesniak, JB Biggins, PD Jeffrey, J Jiang, KR Rajashankar, ... Nature Structural Biology 8 (6), 545-551, 2001 | 165 | 2001 |