| Multistep engineering of pyrrolysyl-tRNA synthetase to genetically encode Nɛ-(o-azidobenzyloxycarbonyl) lysine for site-specific protein modification T Yanagisawa, R Ishii, R Fukunaga, T Kobayashi, K Sakamoto, ... Chemistry & biology 15 (11), 1187-1197, 2008 | 405 | 2008 |
| Adding l-lysine derivatives to the genetic code of mammalian cells with engineered pyrrolysyl-tRNA synthetases T Mukai, T Kobayashi, N Hino, T Yanagisawa, K Sakamoto, S Yokoyama Biochemical and biophysical research communications 371 (4), 818-822, 2008 | 341 | 2008 |
| A paralog of lysyl-tRNA synthetase aminoacylates a conserved lysine residue in translation elongation factor P T Yanagisawa, T Sumida, R Ishii, C Takemoto, S Yokoyama Nature structural & molecular biology 17 (9), 1136-1143, 2010 | 173 | 2010 |
| Relationship of protein structure of isoleucyl-tRNA synthetase with pseudomonic acid resistance of Escherichia coli. A proposed mode of action of pseudomonic acid as an … T Yanagisawa, JT Lee, HC Wu, M Kawakami Journal of Biological Chemistry 269 (39), 24304-24309, 1994 | 124 | 1994 |
| Crystallographic studies on multiple conformational states of active-site loops in pyrrolysyl-tRNA synthetase T Yanagisawa, R Ishii, R Fukunaga, T Kobayashi, K Sakamoto, ... Journal of molecular biology 378 (3), 634-652, 2008 | 121 | 2008 |
| Recognition of non-α-amino substrates by pyrrolysyl-tRNA synthetase T Kobayashi, T Yanagisawa, K Sakamoto, S Yokoyama Journal of molecular biology 385 (5), 1352-1360, 2009 | 101 | 2009 |
| Reassignment of a rare sense codon to a non-canonical amino acid in Escherichia coli T Mukai, A Yamaguchi, K Ohtake, M Takahashi, A Hayashi, F Iraha, S Kira, ... Nucleic acids research 43 (16), 8111-8122, 2015 | 94 | 2015 |
| Genetic-code evolution for protein synthesis with non-natural amino acids T Mukai, T Yanagisawa, K Ohtake, M Wakamori, J Adachi, N Hino, A Sato, ... Biochemical and biophysical research communications 411 (4), 757-761, 2011 | 81 | 2011 |
| Crystallization and preliminary X-ray crystallographic analysis of the catalytic domain of pyrrolysyl-tRNA synthetase from the methanogenic archaeon Methanosarcina mazei T Yanagisawa, R Ishii, R Fukunaga, O Nureki, S Yokoyama Acta Crystallographica Section F: Structural Biology and Crystallization …, 2006 | 62 | 2006 |
| Wide-range protein photo-crosslinking achieved by a genetically encoded N ε-(benzyloxycarbonyl) lysine derivative with a diazirinyl moiety T Yanagisawa, N Hino, F Iraha, T Mukai, K Sakamoto, S Yokoyama Molecular BioSystems 8 (4), 1131-1135, 2012 | 57 | 2012 |
| Molecular cloning and crystal structural analysis of a novel β-N-acetylhexosaminidase from Paenibacillus sp. TS12 capable of degrading glycosphingolipids T Sumida, R Ishii, T Yanagisawa, S Yokoyama, M Ito Journal of molecular biology 392 (1), 87-99, 2009 | 55 | 2009 |
| Neisseria meningitidis Translation Elongation Factor P and Its Active-Site Arginine Residue Are Essential for Cell Viability T Yanagisawa, H Takahashi, T Suzuki, A Masuda, N Dohmae, ... PLoS One 11 (2), e0147907, 2016 | 51 | 2016 |
| How does Pseudomonas fluorescens avoid suicide from its antibiotic pseudomonic acid?: Evidence for two evolutionarily distinct isoleucyl-tRNA synthetases conferring self-defense T Yanagisawa, M Kawakami Journal of Biological Chemistry 278 (28), 25887-25894, 2003 | 50 | 2003 |
| Incorporation of a doubly functionalized synthetic amino acid into proteins for creating chemical and light-induced conjugates A Yamaguchi, T Matsuda, K Ohtake, T Yanagisawa, S Yokoyama, ... Bioconjugate Chemistry 27 (1), 198-206, 2016 | 48 | 2016 |
| Structural basis for genetic-code expansion with bulky lysine derivatives by an engineered pyrrolysyl-tRNA synthetase T Yanagisawa, M Kuratani, E Seki, N Hino, K Sakamoto, S Yokoyama Cell Chemical Biology 26 (7), 936-949. e13, 2019 | 46 | 2019 |
| Multiple Site‐Specific Installations of Nε‐Monomethyl‐L‐Lysine into Histone Proteins by Cell‐Based and Cell‐Free Protein Synthesis T Yanagisawa, M Takahashi, T Mukai, S Sato, M Wakamori, M Shirouzu, ... ChemBioChem 15 (12), 1830-1838, 2014 | 44 | 2014 |
| Meningococcal PilV potentiates Neisseria meningitidis type IV pilus-mediated internalization into human endothelial and epithelial cells H Takahashi, T Yanagisawa, KS Kim, S Yokoyama, M Ohnishi Infection and immunity 80 (12), 4154-4166, 2012 | 34 | 2012 |
| Crystal structures of tyrosyl-tRNA synthetases from Archaea M Kuratani, H Sakai, M Takahashi, T Yanagisawa, T Kobayashi, ... Journal of molecular biology 355 (3), 395-408, 2006 | 34 | 2006 |
| Expanded genetic code technologies for incorporating modified lysine at multiple sites T Yanagisawa, T Umehara, K Sakamoto, S Yokoyama Chembiochem: a European journal of chemical biology 15 (15), 2181-2187, 2014 | 32 | 2014 |
| Inhibition of the slow inward current and the time-dependent outward current of mammalian ventricular muscle by gentamicin N Hino, R Ochi, T Yanagisawa Pflügers Archiv 394, 243-249, 1982 | 31 | 1982 |
