Microglia dictate the impact of saturated fat consumption on hypothalamic inflammation and neuronal function M Valdearcos, MM Robblee, DI Benjamin, DK Nomura, AW Xu, ... Cell reports 9 (6), 2124-2138, 2014 | 576 | 2014 |
Microglial inflammatory signaling orchestrates the hypothalamic immune response to dietary excess and mediates obesity susceptibility M Valdearcos, JD Douglass, MM Robblee, MD Dorfman, DR Stifler, ... Cell metabolism 26 (1), 185-197. e3, 2017 | 410 | 2017 |
Microglia mediate postoperative hippocampal inflammation and cognitive decline in mice X Feng, M Valdearcos, Y Uchida, D Lutrin, M Maze, SK Koliwad JCI insight 2 (7), 2017 | 273 | 2017 |
Subcellular localization and role of lipin-1 in human macrophages M Valdearcos, E Esquinas, C Meana, L Gil-de-Gómez, C Guijas, ... The Journal of Immunology 186 (10), 6004-6013, 2011 | 206 | 2011 |
Hypothalamic inflammation in the control of metabolic function M Valdearcos, AW Xu, SK Koliwad Annual review of physiology 77 (1), 131-160, 2015 | 188 | 2015 |
Saturated fatty acids engage an IRE1α-dependent pathway to activate the NLRP3 inflammasome in myeloid cells MM Robblee, CC Kim, JP Abate, M Valdearcos, KLM Sandlund, ... Cell reports 14 (11), 2611-2623, 2016 | 183 | 2016 |
Lipin-2 reduces proinflammatory signaling induced by saturated fatty acids in macrophages M Valdearcos, E Esquinas, C Meana, L Peña, L Gil-de-Gómez, J Balsinde, ... Journal of Biological Chemistry 287 (14), 10894-10904, 2012 | 178 | 2012 |
Requirement of JNK-mediated phosphorylation for translocation of group IVA phospholipase A2 to phagosomes in human macrophages J Casas, C Meana, E Esquinas, M Valdearcos, J Pindado, J Balsinde, ... The Journal of Immunology 183 (4), 2767-2774, 2009 | 173 | 2009 |
Interleukin-6 is both necessary and sufficient to produce perioperative neurocognitive disorder in mice J Hu, X Feng, M Valdearcos, D Lutrin, Y Uchida, SK Koliwad, M Maze British journal of anaesthesia 120 (3), 537-545, 2018 | 121 | 2018 |
Lipin-1 integrates lipid synthesis with proinflammatory responses during TLR activation in macrophages C Meana, L Peña, G Lordén, E Esquinas, C Guijas, M Valdearcos, ... The Journal of Immunology 193 (9), 4614-4622, 2014 | 115 | 2014 |
mTORC1-to-AMPK switching underlies β cell metabolic plasticity during maturation and diabetes R Jaafar, S Tran, AN Shah, G Sun, M Valdearcos, P Marchetti, M Masini, ... The Journal of clinical investigation 129 (10), 4124-4137, 2019 | 108 | 2019 |
The cationic cluster of group IVA phospholipase A2 (Lys488/Lys541/Lys543/Lys544) is involved in translocation of the enzyme to phagosomes in human macrophages J Casas, M Valdearcos, J Pindado, J Balsinde, MA Balboa Journal of lipid research 51 (2), 388-399, 2010 | 108 | 2010 |
Acute lesioning and rapid repair of hypothalamic neurons outside the blood-brain barrier E Yulyaningsih, IA Rudenko, M Valdearcos, E Dahlén, E Vagena, A Chan, ... Cell reports 19 (11), 2257-2271, 2017 | 57 | 2017 |
Critical role for cytosolic group IVA phospholipase A2 in early adipocyte differentiation and obesity L Peña, C Meana, AM Astudillo, G Lordén, M Valdearcos, H Sato, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 54 | 2016 |
Leptin potentiates astrogenesis in the developing hypothalamus DM Rottkamp, IA Rudenko, MT Maier, S Roshanbin, E Yulyaningsih, ... Molecular metabolism 4 (11), 881-889, 2015 | 44 | 2015 |
Hypothalamic microglia as potential regulators of metabolic physiology M Valdearcos, MG Myers Jr, SK Koliwad Nature Metabolism 1 (3), 314-320, 2019 | 42 | 2019 |
Blocking Kv1. 3 potassium channels prevents postoperative neuroinflammation and cognitive decline without impairing wound healing in mice IK Lai, M Valdearcos, K Morioka, S Saxena, X Feng, R Li, Y Uchida, ... British journal of anaesthesia 125 (3), 298-307, 2020 | 28 | 2020 |
Microglial lipid biology in the hypothalamic regulation of metabolic homeostasis A Folick, SK Koliwad, M Valdearcos Frontiers in Endocrinology 12, 668396, 2021 | 21 | 2021 |
Metabolic factors in the regulation of hypothalamic innate immune responses in obesity A Folick, RT Cheang, M Valdearcos, SK Koliwad Experimental & Molecular Medicine 54 (4), 393-402, 2022 | 14 | 2022 |
ASB4 modulates central melanocortinergic neurons and calcitonin signaling to control satiety and glucose homeostasis E Vagena, J Crneta, P Engström, L He, E Yulyaningsih, NL Korpel, ... Science signaling 15 (733), eabj8204, 2022 | 12 | 2022 |