| Reactive oxygen species and cancer paradox: to promote or to suppress? S Galadari, A Rahman, S Pallichankandy, F Thayyullathil Free Radical Biology and Medicine 104, 144-164, 2017 | 909 | 2017 |
| Rapid reactive oxygen species (ROS) generation induced by curcumin leads to caspase-dependent and-independent apoptosis in L929 cells F Thayyullathil, S Chathoth, A Hago, M Patel, S Galadari Free Radical Biology and Medicine 45 (10), 1403-1412, 2008 | 278 | 2008 |
| Role of ceramide in diabetes mellitus: evidence and mechanisms S Galadari, A Rahman, S Pallichankandy, A Galadari, F Thayyullathil Lipids in health and disease 12, 1-16, 2013 | 221 | 2013 |
| Tumor suppressive functions of ceramide: evidence and mechanisms S Galadari, A Rahman, S Pallichankandy, F Thayyullathil Apoptosis 20, 689-711, 2015 | 101 | 2015 |
| ROS-dependent activation of autophagy is a critical mechanism for the induction of anti-glioma effect of sanguinarine S Pallichankandy, A Rahman, F Thayyullathil, S Galadari Free Radical Biology and Medicine 89, 708-720, 2015 | 97 | 2015 |
| Molecular targets and anticancer potential of sanguinarine—A benzophenanthridine alkaloid S Galadari, A Rahman, S Pallichankandy, F Thayyullathil Phytomedicine 34, 143-153, 2017 | 86 | 2017 |
| Acid sphingomyelinase-dependent autophagic degradation of GPX4 is critical for the execution of ferroptosis F Thayyullathil, AR Cheratta, A Alakkal, K Subburayan, S Pallichankandy, ... Cell death & disease 12 (1), 26, 2021 | 68 | 2021 |
| ROS-dependent prostate apoptosis response-4 (Par-4) up-regulation and ceramide generation are the prime signaling events associated with curcumin-induced autophagic cell death … F Thayyullathil, A Rahman, S Pallichankandy, M Patel, S Galadari FEBS open bio 4, 763-776, 2014 | 66 | 2014 |
| Modulation of curcumin-induced Akt phosphorylation and apoptosis by PI3K inhibitor in MCF-7 cells J Kizhakkayil, F Thayyullathil, S Chathoth, A Hago, M Patel, S Galadari Biochemical and biophysical research communications 394 (3), 476-481, 2010 | 65 | 2010 |
| Effects of the endogenous cannabinoid anandamide on voltage‐dependent sodium and calcium channels in rat ventricular myocytes LT Al Kury, OI Voitychuk, KHS Yang, FT Thayyullathil, P Doroshenko, ... British journal of pharmacology 171 (14), 3485-3498, 2014 | 63 | 2014 |
| Critical role of H2O2 in mediating sanguinarine-induced apoptosis in prostate cancer cells via facilitating ceramide generation, ERK1/2 phosphorylation, and Par-4 cleavage A Rahman, S Pallichankandy, F Thayyullathil, S Galadari Free Radical Biology and Medicine 134, 527-544, 2019 | 60 | 2019 |
| Caspase-3 mediated release of SAC domain containing fragment from Par-4 is necessary for the sphingosine-induced apoptosis in Jurkat cells F Thayyullathil, S Pallichankandy, A Rahman, J Kizhakkayil, S Chathoth, ... Journal of molecular signaling 8 (1), 1-13, 2013 | 50 | 2013 |
| Glutathione regulates caspase-dependent ceramide production and curcumin-induced apoptosis in human leukemic cells J Kizhakkayil, F Thayyullathil, S Chathoth, A Hago, M Patel, S Galadari Free Radical Biology and Medicine 52 (9), 1854-1864, 2012 | 49 | 2012 |
| Protein phosphatase 1‐dependent dephosphorylation of Akt is the prime signaling event in sphingosine‐induced apoptosis in Jurkat cells F Thayyullathil, S Chathoth, A Shahin, J Kizhakkayil, A Hago, M Patel, ... Journal of cellular biochemistry 112 (4), 1138-1153, 2011 | 44 | 2011 |
| Superoxide-mediated ferroptosis in human cancer cells induced by sodium selenite K Subburayan, F Thayyullathil, S Pallichankandy, AR Cheratta, ... Translational oncology 13 (11), 100843, 2020 | 43 | 2020 |
| Hydrogen peroxide/ceramide/Akt signaling axis play a critical role in the antileukemic potential of sanguinarine A Rahman, F Thayyullathil, S Pallichankandy, S Galadari Free Radical Biology and Medicine 96, 273-289, 2016 | 39 | 2016 |
| Par-4-dependent p53 up-regulation plays a critical role in thymoquinone-induced cellular senescence in human malignant glioma cells K Subburayan, F Thayyullathil, S Pallichankandy, A Rahman, S Galadari Cancer Letters 426, 80-97, 2018 | 33 | 2018 |
| Prostate apoptosis response-4 and tumor suppression: It’s not just about apoptosis anymore AR Cheratta, F Thayyullathil, S Pallichankandy, K Subburayan, A Alakkal, ... Cell Death & Disease 12 (1), 47, 2021 | 20 | 2021 |
| Par-4 regulates autophagic cell death in human cancer cells via upregulating p53 and BNIP3 F Thayyullathil, AR Cheratta, S Pallichankandy, K Subburayan, S Tariq, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1867 (7), 118692, 2020 | 18 | 2020 |
| Sanguinarine Induces H2O2-Dependent Apoptosis and Ferroptosis in Human Cervical Cancer A Alakkal, F Thayyullathil, S Pallichankandy, K Subburayan, AR Cheratta, ... Biomedicines 10 (8), 1795, 2022 | 16 | 2022 |
