The ceramide kinase inhibitor NVP‐231 inhibits breast and lung cancer cell proliferation by inducing M phase arrest and subsequent cell death O Pastukhov, S Schwalm, U Zangemeister‐Wittke, D Fabbro, F Bornancin, ... British journal of pharmacology 171 (24), 5829-5844, 2014 | 72 | 2014 |
Severe glucose-6-phosphate dehydrogenase deficiency leads to susceptibility to infection and absent NETosis U Siler, S Romao, E Tejera, O Pastukhov, E Kuzmenko, RG Valencia, ... Journal of Allergy and Clinical Immunology 139 (1), 212-219. e3, 2017 | 70 | 2017 |
Loss of sphingosine kinase‐1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin‐induced DNA damage A Huwiler, N Kotelevets, C Xin, O Pastukhov, J Pfeilschifter, ... British journal of pharmacology 162 (2), 532-543, 2011 | 49 | 2011 |
Human DOCK2 deficiency: report of a novel mutation and evidence for neutrophil dysfunction L Moens, M Gouwy, B Bosch, O Pastukhov, A Nieto-Patlàn, U Siler, ... Journal of clinical immunology 39, 298-308, 2019 | 37 | 2019 |
Ceramide kinase contributes to proliferation but not to prostaglandin E2 formation in renal mesangial cells and fibroblasts O Pastukhov, S Schwalm, I Römer, U Zangemeister-Wittke, J Pfeilschifter, ... Cellular Physiology and Biochemistry 34 (1), 119-133, 2014 | 36 | 2014 |
The ω3‐polyunsaturated fatty acid derivatives AVX001 and AVX002 directly inhibit cytosolic phospholipase A2 and suppress PGE2 formation in mesangial cells A Huwiler, AJ Feuerherm, B Sakem, O Pastukhov, I Filipenko, T Nguyen, ... British journal of pharmacology 167 (8), 1691-1701, 2012 | 34 | 2012 |
A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: implication for treating hyperproliferative disorders A Huwiler, F Bourquin, N Kotelevets, O Pastukhov, G Capitani, MG Grütter, ... PLoS One 6 (8), e22436, 2011 | 28 | 2011 |
High levels of IL-18 and IFN-γ in chronically inflamed tissue in chronic granulomatous disease V Meda Spaccamela, RG Valencia, O Pastukhov, A Duppenthaler, ... Frontiers in immunology 10, 2236, 2019 | 23 | 2019 |
Inhibitors of secreted phospholipase A2 suppress the release of PGE2 in renal mesangial cells S Vasilakaki, E Barbayianni, V Magrioti, O Pastukhov, ... Bioorganic & medicinal chemistry 24 (13), 3029-3034, 2016 | 13 | 2016 |
CRISPR-directed therapeutic correction at the NCF1 locus is challenged by frequent incidence of chromosomal deletions D Wrona, O Pastukhov, RS Pritchard, F Raimondi, J Tchinda, M Jinek, ... Molecular Therapy Methods & Clinical Development 17, 936-943, 2020 | 11 | 2020 |
Small Peptides Able to Suppress Prostaglandin E2 Generation in Renal Mesangial Cells S Vasilakaki, O Pastukhov, T Mavromoustakos, A Huwiler, G Kokotos Molecules 23 (1), 158, 2018 | 9 | 2018 |
Targeted knock-in of NCF1 cDNA into the NCF2 locus leads to myeloid phenotypic correction of p47phox-deficient chronic granulomatous disease KM Siow, M Güngör, D Wrona, F Raimondi, O Pastukhov, P Tsapogas, ... Molecular Therapy-Nucleic Acids 35 (3), 2024 | | 2024 |
Targeted knock-in of NCF1 cDNA into the NCF2 locus leads to myeloid phenotypic correction of p47phox-deficient chronic granulomatous disease KM Siow, M Güngör, D Wrona, F Raimondi, O Pastukhov, P Tsapogas, ... Molecular Therapy. Nucleic Acids 35 (3), 2024 | | 2024 |
Novel transduction enhancers and uses thereof O Pastukhov, U Siler, J Reichenbach US Patent App. 17/926,757, 2023 | | 2023 |
Study of vasculoprotective effects of gel "Gingoven" - a new medicine to treat chronic venous insufficiency in the legs [article in Ukrainian] Yakovleva L, Pastukhov O News in pharmacy 4, 68-71, 2009 | | 2009 |
Comparative study focused on specific pharmacological activity of paracetamol generics produced by different manufacturers [article in Ukrainian] Drogovoz S, Pastukhov O, Koval O Rational pharmacotherapy 3, 78-81, 2009 | | 2009 |
Pharmacoeconomic aspects of medical treatment of age-related macular degeneration [article in Ukrainian] Bezdetko N, Bezdetko P, Pastukhov O Clinical pharmacy 13, 44-47, 2009 | | 2009 |
Study of anti-exudative effects of gel "Gingoven" - a new medicine to treat chronic venous insufficiency in the legs [article in Ukrainian] Yakovleva L, Trutaev I, Pastukhov O, Kovaleva E Clinical pharmacy 3, 46-49, 2009 | | 2009 |