A series of novel terpyridine-skeleton molecule derivants inhibit tumor growth and metastasis by targeting topoisomerases HB Kwon, C Park, KH Jeon, E Lee, SE Park, KY Jun, TM Kadayat, ... Journal of Medicinal Chemistry 58 (3), 1100-1122, 2015 | 104 | 2015 |
Mutations in SOHLH1 gene associate with nonobstructive Azoospermia Y Choi, S Jeon, M Choi, M Lee, M Park, DR Lee, KY Jun, Y Kwon, OH Lee, ... Human mutation 31 (7), 788-793, 2010 | 104 | 2010 |
μParaflo™ biochip for nucleic acid and protein analysis Q Zhu, A Hong, N Sheng, X Zhang, A Matejko, KY Jun, O Srivannavit, ... Microarrays: Volume 2: Applications and Data Analysis, 287-312, 2007 | 99 | 2007 |
Effect of conjugated linoleic acid, μ-calpain inhibitor, on pathogenesis of Alzheimer's disease E Lee, JE Eom, HL Kim, KH Baek, KY Jun, HJ Kim, M Lee, I Mook-Jung, ... Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2013 | 60 | 2013 |
Synthesis, biological evaluation, and molecular docking study of 3-(3′-heteroatom substituted-2′-hydroxy-1′-propyloxy) xanthone analogues as novel topoisomerase IIα … KY Jun, EY Lee, MJ Jung, OH Lee, ES Lee, HYP Choo, Y Na, Y Kwon European journal of medicinal chemistry 46 (6), 1964-1971, 2011 | 59 | 2011 |
Design, synthesis, topoisomerase I & II inhibitory activity, antiproliferative activity, and structure–activity relationship study of pyrazoline derivatives: An ATP-competitive … P Ahmad, H Woo, KY Jun, AA Kadi, HA Abdel-Aziz, Y Kwon, ... Bioorganic & Medicinal Chemistry 24 (8), 1898-1908, 2016 | 51 | 2016 |
IP‐COSY, a totally in‐phase and sensitive COSY experiment Y Xia, G Legge, KY Jun, Y Qi, H Lee, X Gao Magnetic Resonance in Chemistry 43 (5), 372-379, 2005 | 47 | 2005 |
Benzo[b]tryptanthrin Inhibits MDR1, Topoisomerase Activity, and Reverses Adriamycin Resistance in Breast Cancer Cells KY Jun, SE Park, JL Liang, Y Jahng, Y Kwon ChemMedChem 10 (5), 827-835, 2015 | 44 | 2015 |
Hydroxylated 2, 4-diphenyl indenopyridine derivatives as a selective non-intercalative topoisomerase IIα catalytic inhibitor TM Kadayat, C Park, KY Jun, TBT Magar, G Bist, HY Yoo, Y Kwon, ES Lee European Journal of Medicinal Chemistry 90, 302-314, 2015 | 41 | 2015 |
Bacterial nucleoside catabolism controls quorum sensing and commensal-to-pathogen transition in the Drosophila gut EK Kim, KA Lee, M Kyung, KY Jun, SH Seo, D Hwang, Y Kwon, WJ Lee Cell Host & Microbe 27 (3), 345-357. e6, 2020 | 38 | 2020 |
Discovery of dihydroxylated 2, 4-diphenyl-6-thiophen-2-yl-pyridine as a non-intercalative DNA-binding topoisomerase II-specific catalytic inhibitor KY Jun, H Kwon, SE Park, E Lee, R Karki, P Thapa, JH Lee, ES Lee, ... European journal of medicinal chemistry 80, 428-438, 2014 | 38 | 2014 |
Synthesis, antitumor activity, and structure–activity relationship study of trihydroxylated 2, 4, 6-triphenyl pyridines as potent and selective topoisomerase II inhibitors R Karki, C Park, KY Jun, JG Jee, JH Lee, P Thapa, TM Kadayat, Y Kwon, ... European journal of medicinal chemistry 84, 555-565, 2014 | 37 | 2014 |
Neuroprotective effect of undecylenic acid extracted from Ricinus communis L. through inhibition of μ-calpain E Lee, JE Eom, HL Kim, DH Kang, KY Jun, DS Jung, Y Kwon European journal of pharmaceutical sciences 46 (1-2), 17-25, 2012 | 34 | 2012 |
Synthesis and biological activity of 2, 4-di-p-phenolyl-6-2-furanyl-pyridine as a potent topoisomerase II poison R Karki, C Park, KY Jun, TM Kadayat, ES Lee, Y Kwon European Journal of Medicinal Chemistry 90, 360-378, 2015 | 33 | 2015 |
Synthesis and Biological Properties of Luotonin A Derivatives. AFMM Rahman, DH Kim, JL Liang, ES Lee, Y Na, KY Jun, Y Kwon, ... ChemInform 40 (10), i, 2009 | 32 | 2009 |
A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds MA Hashem, KY Jun, E Lee, S Lim, HYP Choo, Y Kwon Molecules and Cells 26 (6), 625-630, 2008 | 32 | 2008 |
Novel 2-aryl-4-(4′-hydroxyphenyl)-5H-indeno [1, 2-b] pyridines as potent DNA non-intercalative topoisomerase catalytic inhibitors S Park, TM Kadayat, KY Jun, TBT Magar, G Bist, A Shrestha, ES Lee, ... European journal of medicinal chemistry 125, 14-28, 2017 | 31 | 2017 |
Neuroprotective effect of synthetic chalcone derivatives as competitive dual inhibitors against μ-calpain and cathepsin B through the downregulation of tau phosphorylation and … KH Jeon, E Lee, KY Jun, JE Eom, SY Kwak, Y Na, Y Kwon European journal of medicinal chemistry 121, 433-444, 2016 | 31 | 2016 |
Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents P Thapa, KY Jun, TM Kadayat, C Park, Z Zheng, TBT Magar, G Bist, ... Bioorganic & Medicinal Chemistry 23 (19), 6454-6466, 2015 | 29 | 2015 |
Identification of 3-acetyl-2-aminoquinolin-4-one as a novel, nonpeptidic scaffold for specific calpain inhibitory activity DH Kang, KY Jun, JP Lee, CS Pak, Y Na, Y Kwon Journal of medicinal chemistry 52 (9), 3093-3097, 2009 | 29 | 2009 |