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Maarten Jacquemyn
Maarten Jacquemyn
Senior Scientist
在 kuleuven.Be 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2
J Baggen, L Persoons, E Vanstreels, S Jansen, D Van Looveren, ...
Nature Genetics 53 (4), 435-444, 2021
1732021
Identifying drug-target selectivity of small-molecule CRM1/XPO1 inhibitors by CRISPR/Cas9 genome editing
JE Neggers, T Vercruysse, M Jacquemyn, E Vanstreels, E Baloglu, ...
Chemistry & biology 22 (1), 107-116, 2015
1472015
Target identification of small molecules using large-scale CRISPR-Cas mutagenesis scanning of essential genes
JE Neggers, B Kwanten, T Dierckx, H Noguchi, A Voet, L Bral, K Minner, ...
Nature Communications 9 (1), 502, 2018
1122018
The second-generation exportin-1 inhibitor KPT-8602 demonstrates potent activity against acute lymphoblastic leukemia
T Vercruysse, J De Bie, JE Neggers, M Jacquemyn, E Vanstreels, ...
Clinical Cancer Research 23 (10), 2528-2541, 2017
622017
TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
J Baggen, M Jacquemyn, L Persoons, E Vanstreels, VE Pye, AG Wrobel, ...
Cell 186 (16), 3427-3442. e22, 2023
502023
The material properties of a bacterial-derived biomolecular condensate tune biological function in natural and synthetic systems
K Lasker, S Boeynaems, V Lam, D Scholl, E Stainton, A Briner, ...
Nature Communications 13 (1), 5643, 2022
502022
ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization
GHP Tazelaar, S Boeynaems, M De Decker, JJFA van Vugt, L Kool, ...
Brain communications 2 (2), fcaa064, 2020
502020
Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas
N Saenz-Ponce, R Pillay, LM de Long, T Kashyap, C Argueta, ...
Science translational medicine 10 (447), eaar7223, 2018
392018
STK 38 kinase acts as XPO 1 gatekeeper regulating the nuclear export of autophagy proteins and other cargoes
APJ Martin, M Jacquemyn, J Lipecka, C Chhuon, VN Aushev, B Meunier, ...
EMBO reports 20 (11), e48150, 2019
382019
Human exportin-1 is a target for combined therapy of HIV and AIDS related lymphoma
E Boons, E Vanstreels, M Jacquemyn, TC Nogueira, JE Neggers, ...
EBioMedicine 2 (9), 1102-1113, 2015
322015
A modular platform for engineering function of natural and synthetic biomolecular condensates
K Lasker, S Boeynaems, V Lam, E Stainton, M Jacquemyn, D Daelemans, ...
BioRxiv, 2021.02. 03.429226, 2021
242021
Loss of tRNA-modifying enzyme Elp3 activates a p53-dependent antitumor checkpoint in hematopoiesis
A Rosu, N El Hachem, F Rapino, K Rouault-Pierre, J Jorssen, J Somja, ...
Journal of Experimental Medicine 218 (3), e20200662, 2021
172021
CRISPR/Cas9 screen in human iPSC‐derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity
W Guo, H Wang, A Kumar Tharkeshwar, J Couthouis, E Braems, ...
Alzheimer's & Dementia 19 (4), 1245-1259, 2023
142023
enAsCas12a enables CRISPR-directed evolution to screen for functional drug resistance mutations in sequences inaccessible to SpCas9
JE Neggers, M Jacquemyn, T Dierckx, BP Kleinstiver, HJ Thibaut, ...
Molecular Therapy 29 (1), 208-224, 2021
112021
CRISPR-Cas9 recognition of enzymatically synthesized base-modified nucleic acids
H Yang, E Eremeeva, M Abramov, M Jacquemyn, E Groaz, D Daelemans, ...
Nucleic Acids Research 51 (4), 1501-1511, 2023
92023
XPO1 inhibitors represent a novel therapeutic option in Adult T-cell Leukemia, triggering p53-mediated caspase-dependent apoptosis
E Boons, TC Nogueira, T Dierckx, SM Menezes, M Jacquemyn, S Tamir, ...
Blood cancer journal 11 (2), 27, 2021
72021
Identification of TMEM106B as proviral host factor for SARS-CoV-2
J Baggen, L Persoons, S Jansen, E Vanstreels, M Jacquemyn, ...
BioRxiv, 2020.09. 28.316281, 2020
72020
Selective Inhibitors of Nuclear Export (SINE) Compounds Suppress Both HIV Replication and AIDS Related Lymphoma
D Daelemans, E Boons, E Vanstreels, M Jacquemyn, TC Nogueira, ...
Blood, The Journal of the American Society of Hematology 126 (23), 2751-2751, 2015
12015
Aberrant N-glycosylation in pathogenic variants of adenosine deaminase 2 underlying human ADA2 deficiency
L Ehlers, A Hombrouck, M Wouters, B Pillay, S Delafontaine, G Bucciol, ...
2023
Human ADA2 deficiency is characterized by the absence of an intracellular hypoglycosylated form of adenosine deaminase 2
L Ehlers, A Hombrouck, M Wouters, B Pillay, S Delafontaine, G Bucciol, ...
bioRxiv, 2023.10. 25.564037, 2023
2023
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