| A novel botulinum neurotoxin, previously reported as serotype H, has a hybrid-like structure with regions of similarity to the structures of serotypes A and F and is … SE Maslanka, C Lúquez, JK Dykes, WH Tepp, CL Pier, S Pellett, ... The Journal of infectious diseases 213 (3), 379-385, 2016 | 149 | 2016 |
| Characterization of Botulinum Neurotoxin A Subtypes 1 Through 5 by Investigation of Activities in Mice, in Neuronal Cell Cultures, and In Vitro RCM Whitemarsh, WH Tepp, M Bradshaw, G Lin, CL Pier, JM Scherf, ... Infection and immunity 81 (10), 3894-3902, 2013 | 126 | 2013 |
| A neuronal cell-based botulinum neurotoxin assay for highly sensitive and specific detection of neutralizing serum antibodies S Pellett, WH Tepp, CM Clancy, GE Borodic, EA Johnson FEBS letters 581 (25), 4803-4808, 2007 | 114 | 2007 |
| Novel application of human neurons derived from induced pluripotent stem cells for highly sensitive botulinum neurotoxin detection RCM Whitemarsh, MJ Strathman, LG Chase, C Stankewicz, WH Tepp, ... Toxicological Sciences 126 (2), 426-435, 2012 | 102 | 2012 |
| Progress in cell based assays for botulinum neurotoxin detection S Pellett Botulinum neurotoxins, 257-285, 2013 | 95 | 2013 |
| Botulinum neurotoxin subtype A2 enters neuronal cells faster than subtype A1 CL Pier, C Chen, WH Tepp, G Lin, KD Janda, JT Barbieri, S Pellett, ... FEBS letters 585 (1), 199-206, 2011 | 94 | 2011 |
| Bimodal modulation of the botulinum neurotoxin protein-conducting channel A Fischer, Y Nakai, LM Eubanks, CM Clancy, WH Tepp, S Pellett, ... Proceedings of the National Academy of Sciences 106 (5), 1330-1335, 2009 | 94 | 2009 |
| In vivo onset and duration of action varies for botulinum neurotoxin A subtypes 1-5 S Pellett, WH Tepp, RCM Whitemarsh, M Bradshaw, EA Johnson Toxicon 107, 37-42, 2015 | 91 | 2015 |
| Current status and future directions of botulinum neurotoxins for targeting pain processing S Pellett, TL Yaksh, R Ramachandran Toxins 7 (11), 4519-4563, 2015 | 87 | 2015 |
| Persistence of botulinum neurotoxin a subtypes 1-5 in primary rat spinal cord cells RCM Whitemarsh, WH Tepp, EA Johnson, S Pellett PLoS one 9 (2), e90252, 2014 | 85 | 2014 |
| Plasmid encoded neurotoxin genes in Clostridium botulinum serotype A subtypes KM Marshall, M Bradshaw, S Pellett, EA Johnson Biochemical and biophysical research communications 361 (1), 49-54, 2007 | 71 | 2007 |
| Comparison of the primary rat spinal cord cell (RSC) assay and the mouse bioassay for botulinum neurotoxin type A potency determination S Pellett, WH Tepp, SI Toth, EA Johnson Journal of pharmacological and toxicological methods 61 (3), 304-310, 2010 | 68 | 2010 |
| Evaluation of adamantane hydroxamates as botulinum neurotoxin inhibitors: synthesis, crystallography, modeling, kinetic and cellular based studies P Šilhár, NR Silvaggi, S Pellett, K Čapková, EA Johnson, KN Allen, ... Bioorganic & medicinal chemistry 21 (5), 1344-1348, 2013 | 63 | 2013 |
| Synthesis/biological evaluation of hydroxamic acids and their prodrugs as inhibitors for Botulinum neurotoxin A light chain H Seki, S Pellett, P Šilhár, GN Stowe, B Blanco, MA Lardy, EA Johnson, ... Bioorganic & Medicinal Chemistry 22 (3), 1208-1217, 2014 | 61 | 2014 |
| The light chain defines the duration of action of botulinum toxin serotype A subtypes S Pellett, M Bradshaw, WH Tepp, CL Pier, RCM Whitemarsh, C Chen, ... MBio 9 (2), 10.1128/mbio. 00089-18, 2018 | 54 | 2018 |
| Purification and characterization of botulinum neurotoxin FA from a genetically modified Clostridium botulinum strain S Pellett, WH Tepp, M Bradshaw, SR Kalb, JK Dykes, G Lin, EM Nawrocki, ... Msphere 1 (1), 10.1128/msphere. 00100-15, 2016 | 47 | 2016 |
| Sensitive and quantitative detection of botulinum neurotoxin in neurons derived from mouse embryonic stem cells S Pellett, Z Du, CL Pier, WH Tepp, S Zhang, EA Johnson Biochemical and biophysical research communications 404 (1), 388-392, 2011 | 40 | 2011 |
| Benzylidene cyclopentenediones: First irreversible inhibitors against botulinum neurotoxin A’s zinc endopeptidase K Čapková, MS Hixon, S Pellett, JT Barbieri, EA Johnson, KD Janda Bioorganic & medicinal chemistry letters 20 (1), 206-208, 2010 | 37 | 2010 |
| Human Induced Pluripotent Stem Cell Derived Neuronal Cells Cultured on Chemically-Defined Hydrogels for Sensitive In Vitro Detection of Botulinum Neurotoxin S Pellett, MP Schwartz, WH Tepp, R Josephson, JM Scherf, CL Pier, ... Scientific reports 5 (1), 14566, 2015 | 36 | 2015 |
| Comparison of the catalytic properties of the botulinum neurotoxin subtypes A1 and A5 D Wang, J Krilich, S Pellett, J Baudys, WH Tepp, JR Barr, EA Johnson, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (12), 2722-2728, 2013 | 35 | 2013 |
