关注
Kyle Cromer
Kyle Cromer
Assistant Professor, Dept. of Surgery, UCSF
在 ucsf.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Identification of preexisting adaptive immunity to Cas9 proteins in humans
CT Charlesworth, PS Deshpande, DP Dever, J Camarena, VT Lemgart, ...
Nature medicine 25 (2), 249-254, 2019
9502019
Highly efficient and marker-free genome editing of human pluripotent stem cells by CRISPR-Cas9 RNP and AAV6 donor-mediated homologous recombination
RM Martin, K Ikeda, MK Cromer, N Uchida, T Nishimura, R Romano, ...
Cell stem cell 24 (5), 821-828. e5, 2019
1712019
Identification of somatic mutations in parathyroid tumors using whole-exome sequencing
MK Cromer, LF Starker, M Choi, R Udelsman, C Nelson-Williams, ...
The Journal of Clinical Endocrinology & Metabolism 97 (9), E1774-E1781, 2012
1592012
Global transcriptional response to CRISPR/Cas9-AAV6-based genome editing in CD34+ hematopoietic stem and progenitor cells
MK Cromer, S Vaidyanathan, DE Ryan, B Curry, AB Lucas, J Camarena, ...
Molecular Therapy 26 (10), 2431-2442, 2018
1132018
Development of β-globin gene correction in human hematopoietic stem cells as a potential durable treatment for sickle cell disease
A Lattanzi, J Camarena, P Lahiri, H Segal, W Srifa, CA Vakulskas, ...
Science translational medicine 13 (598), eabf2444, 2021
1052021
Priming human repopulating hematopoietic stem and progenitor cells for Cas9/sgRNA gene targeting
CT Charlesworth, J Camarena, MK Cromer, S Vaidyanathan, RO Bak, ...
Molecular Therapy-Nucleic Acids 12, 89-104, 2018
922018
Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards
RM Martin, JL Fowler, MK Cromer, BJ Lesch, E Ponce, N Uchida, ...
Nature communications 11 (1), 2713, 2020
852020
Neomorphic effects of recurrent somatic mutations in Yin Yang 1 in insulin-producing adenomas
MK Cromer, M Choi, C Nelson-Williams, AL Fonseca, JW Kunstman, ...
Proceedings of the National Academy of Sciences 112 (13), 4062-4067, 2015
742015
Gene replacement of α-globin with β-globin restores hemoglobin balance in β-thalassemia-derived hematopoietic stem and progenitor cells
MK Cromer, J Camarena, RM Martin, BJ Lesch, CA Vakulskas, NM Bode, ...
Nature medicine 27 (4), 677-687, 2021
662021
Ultra-deep sequencing validates safety of CRISPR/Cas9 genome editing in human hematopoietic stem and progenitor cells
MK Cromer, VV Barsan, E Jaeger, M Wang, JP Hampton, F Chen, ...
Nature Communications 13 (1), 4724, 2022
252022
High-efficiency transgene integration by homology-directed repair in human primary cells using DNA-PKcs inhibition
S Selvaraj, WN Feist, S Viel, S Vaidyanathan, AM Dudek, M Gastou, ...
Nature Biotechnology, 1-14, 2023
212023
CRISPR nuclease off-target activity and mitigation strategies
B Wienert, MK Cromer
Frontiers in Genome Editing 4, 1050507, 2022
202022
Comparative analysis of CRISPR off-target discovery tools following ex vivo editing of CD34+ hematopoietic stem and progenitor cells
MK Cromer, KR Majeti, GR Rettig, K Murugan, GL Kurgan, NM Bode, ...
Molecular Therapy 31 (4), 1074-1087, 2023
13*2023
Improved genome editing through inhibition of FANCM and members of the BTR dissolvase complex
G de Alencastro, F Puzzo, M Pavel-Dinu, F Zhang, S Pillay, K Majzoub, ...
Molecular Therapy 29 (3), 1016-1027, 2021
102021
Transient inhibition of 53BP1 increases the frequency of targeted integration in human hematopoietic stem and progenitor cells
R Baik, MK Cromer, SE Glenn, CA Vakulskas, KO Chmielewski, ...
Nature Communications 15 (1), 111, 2024
52024
Enhancement of erythropoietic output by Cas9-mediated insertion of a natural variant in haematopoietic stem and progenitor cells
SE Luna, J Camarena, JP Hampton, KR Majeti, CT Charlesworth, ...
Nature Biomedical Engineering, 1-13, 2024
3*2024
Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells
JL Fowler, SL Zheng, A Nguyen, A Chen, X Xiong, T Chai, JY Chen, ...
Developmental Cell 59 (9), 1110-1131. e22, 2024
12024
Engineering inducible signaling receptors to enable erythropoietin-free erythropoiesis
AP Shah, KR Majeti, FK Ekman, S Selvaraj, E Soupene, P Chati, R Sinha, ...
bioRxiv, 2024.04. 12.589260, 2024
2024
410.8: Improving the safety of stem-cell-derived beta cell transplantation with an inducible safety switch
SN Chu, NS Amirruddin, DK Sharma, IC Sierra, PG Stock, JB Sneddon, ...
Transplantation 107 (10S2), 165-166, 2023
2023
Dual α-globin and truncated EPO receptor knockin restores hemoglobin production in α-thalassemia-derived red blood cells
SN Chu, E Soupene, B Wienert, H Yin, D Sharma, T McCreary, K Jia, ...
bioRxiv, 2023
2023
系统目前无法执行此操作,请稍后再试。
文章 1–20