A genome-wide haploid genetic screen identifies heparan sulfate-associated genes and the macropinocytosis modulator TMED10 as factors supporting vaccinia virus infection RD Luteijn, F van Diemen, VA Blomen, IGJ Boer, S Manikam Sadasivam, ... Journal of virology 93 (13), 10.1128/jvi. 02160-18, 2019 | 35 | 2019 |
The small molecule inhibitor anle145c thermodynamically traps human islet amyloid peptide in the form of non-cytotoxic oligomers MS Saravanan, S Ryazanov, A Leonov, J Nicolai, P Praest, A Giese, ... Scientific Reports 9 (1), 19023, 2019 | 21 | 2019 |
A single mutation on the human amyloid polypeptide modulates fibril growth and affects the mechanism of amyloid-induced membrane damage ARF Hoffmann, MS Saravanan, O Lequin, JA Killian, L Khemtemourian Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1783-1792, 2018 | 20 | 2018 |
A broad-spectrum antiviral peptide blocks infection of viruses by binding to phosphatidylserine in the viral envelope RD Luteijn, P Praest, F Thiele, SM Sadasivam, K Singethan, JW Drijfhout, ... Cells 9 (9), 1989, 2020 | 16 | 2020 |
Effect of the Novel Amyloid Inhibitor “anle145c” on Aggregation of Islet Amyloid Polypeptide and how it is Modulated by Membranes SM Sadasivam, S Ryazanov, A Leonov, S Roeters, S Wouterson, A Giese, ... Biophysical Journal 110 (3), 420a, 2016 | | 2016 |
The Novel Inhibitor “Anle145C” Efficiently Inhibits Fibril Formation of Islet Amyloid Polypeptide (IAPP) and uses Distinctly Different Modes of Action in the Absence and … MS Saravanan, S Ryazanov, A Leonov, J Seeliger, R Winter, A Giese, ... Biophysical Journal 108 (2), 256a, 2015 | | 2015 |
Interaction of Human Islet Amyloid Polypeptide with Model Membranes in the Presence of a Novel Oligomer Modulator “anle138B” SM Sadasivam, S Ryazanov, A Leonov, A Giese, C Griesinger, JA Killian Biophysical Journal 106 (2), 60a, 2014 | | 2014 |
In vitro investigation on the interaction of human islet amyloid polypeptide with model membranes SM Sadasivam, KJ Antoinette EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS 42, S152-S152, 2013 | | 2013 |
The small molecule inhibitor anle145c thermodynamically traps human islet amyloid polypeptide in the form of non-cytotoxic oligomers MS Saravanan, S Ryazanov, A Leonov, J Nicolai, P Praest, A Giese, ... | | |