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Xolani Henry Makhoba
Xolani Henry Makhoba
PhD Biochemistry
在 unisa.ac.za 的电子邮件经过验证
标题
引用次数
引用次数
年份
Potential impact of the multi-target drug approach in the treatment of some complex diseases
XH Makhoba, C Viegas Jr, RA Mosa, FPD Viegas, OJ Pooe
Drug design, development and therapy, 3235-3249, 2020
1652020
Comparative Characterization of Plasmodium falciparum Hsp70-1 Relative to E. coli DnaK Reveals the Functional Specificity of the Parasite Chaperone
CM Lebepe, PR Matambanadzo, XH Makhoba, I Achilonu, T Zininga, ...
Biomolecules 10 (6), 856, 2020
252020
Use of a chimeric Hsp70 to enhance the quality of recombinant Plasmodium falciparum s-adenosylmethionine decarboxylase protein produced in Escherichia coli
XH Makhoba, A Burger, D Coertzen, T Zininga, LM Birkholtz, A Shonhai
PLoS One 11 (3), e0152626, 2016
202016
Protein PEGylation: navigating recombinant protein stability, aggregation, and bioactivity
LK Zuma, NL Gasa, XH Makhoba, OJ Pooe
BioMed Research International 2022 (1), 8929715, 2022
122022
Potential impact of the multi-target drug approach in the treatment of some complex diseases. Drug Des Devel Ther 14: 3235–3249
XH Makhoba, C Viegas Jr, RA Mosa, FPD Viegas, OJ Pooe
122020
Molecular chaperone assisted expression systems: obtaining pure soluble and active recombinant proteins for structural and therapeutic purposes
XH Makhoba, OJ Pooe, MS Mthembu
OMICS International, 2015
112015
The capture of host cell’s resources: The role of heat shock proteins and polyamines in SARS-COV-2 (COVID-19) pathway to viral infection
XH Makhoba, S Makumire
Biomolecular Concepts 13 (1), 220-229, 2022
102022
The role of pyridine derivatives on the treatment of some complex diseases: A review
XH Makhoba
Recent Developments in the Synthesis and Applications of Pyridines, 143-158, 2023
52023
Potential impact of the multi-target drug approach in the treatment of some complex diseases. Drug Des Devel Ther. 2020; 14: 3235–49
XH Makhoba, C Viegas Jr, RA Mosa, FP Viegas, OJ Pooe
5
A Double Line of Defense: Heat Shock Proteins and Polyamines Act as Contributing Factors to Drug Resistance of some Plasmodium Parasites
XH Makhoba
Plasmodium Species and Drug Resistance, 2021
32021
A comprehensive review of the interaction between COVID-19 spike proteins with mammalian small and major heat shock proteins
LT Navhaya, DM Blessing, M Yamkela, S Godlo, XH Makhoba
Biomolecular Concepts 15 (1), 20220027, 2024
12024
In silico evaluation of heat shock proteins reveals an interplay with polyamines as a survival strategy for the Plasmodium falciparum
G Sesethu, M Nombalentle, M Yamkela, M Anelisa, S Makumire, ...
INNOSC Theranostics and Pharmacological Sciences 7 (1), 1228, 2023
12023
An Undefined Interaction between Polyamines and Heat Shock Proteins Leads to Cellular Protection in Plasmodium falciparum and Proliferating Cells in Various Organisms
E Makhoba, X.H. Ragno, R. Kaiser, Agostinelli
Molecules 28 (4), 1686, 2023
12023
The development of a molecular chaperone-based system to improve the heterologous production of Plasmodium falciparum AdoMetDC protein in E. coli.
XH Makhoba
12011
Medicinal plants as a source of natural remedies in the management of diabetes
XHM Zingisa Sitobo, Liberty Tinotenda Navhaya
INNOSC Theranostics and Pharmacological Sciences. 10 (36922), 1885, 2024
2024
In Silico Analysis of SARS-CoV-2 Non-Structural Proteins Reveals an Interaction with the Host’s Heat Shock Proteins That May Contribute to Viral Replications and Development
M Yamkela, Z Sitobo, XH Makhoba
Current Issues in Molecular Biology 45 (12), 10225-10247, 2023
2023
A Comprehensive Review of Some Heat‐Shock Proteins in the Development and Progression of Human Breast Cancer
XH Makhoba, OJ Pooe
Drug and Therapy Development for Triple Negative Breast Cancer, 237-247, 2023
2023
Drug Repurposing: Challenges and Successes in the Treatment of SARS-CoV-2
XH Makhoba
Drug Repurposing-Advances, Scopes and Opportunities in Drug Discovery, 2023
2023
The Computational Analysis of Plasmodium falciparum Heat Shock Proteins Reveals an Interplay with Polyamines
G Sesethu, M Nombalentle, M Yamnkela, M Anelisa, S Makumire, ...
bioRxiv, 2023.05. 11.540332, 2023
2023
Molecular chaperones and human disease
G Chakafana, S Makumire, XH Makhoba
Frontiers in Molecular Biosciences 9, 1068238, 2022
2022
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