| Structure and activity of putative intronic miRNA promoters AM Monteys, RM Spengler, J Wan, L Tecedor, KA Lennox, Y Xing, ... Rna 16 (3), 495-505, 2010 | 532 | 2010 |
| Transcriptome-wide discovery of microRNA binding sites in human brain RL Boudreau, P Jiang, BL Gilmore, RM Spengler, R Tirabassi, JA Nelson, ... Neuron 81 (2), 294-305, 2014 | 226 | 2014 |
| The extracellular RNA communication consortium: establishing foundational knowledge and technologies for extracellular RNA research S Das, AB Abdel-Mageed, C Adamidi, PD Adelson, KM Akat, E Alsop, ... Cell 177 (2), 231-242, 2019 | 184 | 2019 |
| Adenosine deamination in human transcripts generates novel microRNA binding sites GM Borchert, BL Gilmore, RM Spengler, Y Xing, W Lanier, D Bhattacharya, ... Human molecular genetics 18 (24), 4801-4807, 2009 | 165 | 2009 |
| Comprehensive multi-center assessment of small RNA-seq methods for quantitative miRNA profiling MD Giraldez, RM Spengler, A Etheridge, PM Godoy, AJ Barczak, ... Nature biotechnology 36 (8), 746-757, 2018 | 158 | 2018 |
| Rational design of therapeutic siRNAs: minimizing off-targeting potential to improve the safety of RNAi therapy for Huntington's disease RL Boudreau, RM Spengler, BL Davidson Molecular Therapy 19 (12), 2169-2177, 2011 | 100 | 2011 |
| Functional microRNAs and target sites are created by lineage-specific transposition RM Spengler, CK Oakley, BL Davidson Human molecular genetics 23 (7), 1783-1793, 2014 | 90 | 2014 |
| Phospho‐RNA‐seq: a modified small RNA‐seq method that reveals circulating mRNA and lncRNA fragments as potential biomarkers in human plasma MD Giraldez, RM Spengler, A Etheridge, AJ Goicochea, M Tuck, SW Choi, ... The EMBO journal 38 (11), e101695, 2019 | 85 | 2019 |
| siSPOTR: a tool for designing highly specific and potent siRNAs for human and mouse RL Boudreau, RM Spengler, RH Hylock, BJ Kusenda, HA Davis, ... Nucleic acids research 41 (1), e9-e9, 2013 | 76 | 2013 |
| Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP RM Spengler, X Zhang, C Cheng, JM McLendon, JM Skeie, FL Johnson, ... Nucleic acids research 44 (15), 7120-7131, 2016 | 68 | 2016 |
| Rational design leads to more potent RNA interference against hepatitis B virus: factors effecting silencing efficiency K Keck, EM Volper, RM Spengler, DD Long, CY Chan, Y Ding, ... Molecular Therapy 17 (3), 538-547, 2009 | 55 | 2009 |
| Artificial miRNAs targeting mutant huntingtin show preferential silencing in vitro and in vivo AM Monteys, MJ Wilson, RL Boudreau, RM Spengler, BL Davidson Molecular THerapy-Nucleic Acids 4, 2015 | 52 | 2015 |
| The long non-coding RNA NEAT1 is elevated in polyglutamine repeat expansion diseases and protects from disease gene-dependent toxicities C Cheng, RM Spengler, MS Keiser, AM Monteys, JM Rieders, ... Human molecular genetics 27 (24), 4303-4314, 2018 | 50 | 2018 |
| Human papilloma virus circulating tumor DNA assay predicts treatment response in recurrent/metastatic head and neck squamous cell carcinoma CT Haring, C Bhambhani, C Brummel, B Jewell, E Bellile, MEH Neal, ... Oncotarget 12 (13), 1214, 2021 | 46 | 2021 |
| Single nucleotide seed modification restores in vivo tolerability of a toxic artificial miRNA sequence in the mouse brain AM Monteys, RM Spengler, BD Dufour, MS Wilson, CK Oakley, ... Nucleic acids research 42 (21), 13315-13327, 2014 | 43 | 2014 |
| Human-specific microRNA regulation of FOXO1: implications for microRNA recognition element evolution HS McLoughlin, J Wan, RM Spengler, Y Xing, BL Davidson Human molecular genetics 23 (10), 2593-2603, 2014 | 22 | 2014 |
| Deconvolution of seed and RNA-binding protein crosstalk in RNAi-based functional genomics HI Suzuki, RM Spengler, G Grigelioniene, T Kobayashi, PA Sharp Nature genetics 50 (5), 657-661, 2018 | 20 | 2018 |
| Transcriptome changes in stages of non-alcoholic fatty liver disease J Aljabban, M Rohr, S Syed, K Khorfan, V Borkowski, H Aljabban, M Segal, ... World Journal of Hepatology 14 (7), 1382, 2022 | 7 | 2022 |
| Cis-acting single nucleotide polymorphisms alter MicroRNA-mediated regulation of human brain-expressed transcripts S Ramachandran, SL Coffin, TY Tang, CD Jobaliya, RM Spengler, ... Human Molecular Genetics 25 (22), 4939-4950, 2016 | 7 | 2016 |
| Men who inject opioids exhibit altered tRNA-Gly-GCC isoforms in semen G Gornalusse, RM Spengler, E Sandford, Y Kim, C Levy, M Tewari, ... Molecular human reproduction 29 (3), gaad003, 2023 | 6 | 2023 |
