| The NLRP3 inflammasome pathway: a review of mechanisms and inhibitors for the treatment of inflammatory diseases HM Blevins, Y Xu, S Biby, S Zhang Frontiers in aging neuroscience 14, 879021, 2022 | 151 | 2022 |
| Research advances on anticancer activities of matrine and its derivatives: An updated overview H ur Rashid, Y Xu, Y Muhammad, L Wang, J Jiang European journal of medicinal chemistry 161, 205-238, 2019 | 147 | 2019 |
| Promising anti-inflammatory effects of chalcones via inhibition of cyclooxygenase, prostaglandin E2, inducible NO synthase and nuclear factor κb activities H ur Rashid, Y Xu, N Ahmad, Y Muhammad, L Wang Bioorganic Chemistry 87, 335-365, 2019 | 141 | 2019 |
| Design, synthesis, biological evaluation, and molecular docking of chalcone derivatives as anti-inflammatory agents J Li, D Li, Y Xu, Z Guo, X Liu, H Yang, L Wu, L Wang Bioorganic & medicinal chemistry letters 27 (3), 602-606, 2017 | 71 | 2017 |
| A novel inhibitor targeting NLRP3 inflammasome reduces neuropathology and improves cognitive function in Alzheimer’s disease transgenic mice R Kuwar, A Rolfe, L Di, H Blevins, Y Xu, X Sun, GS Bloom, S Zhang, ... Journal of Alzheimer's Disease 82 (4), 1769-1783, 2021 | 48 | 2021 |
| Design, synthesis and evaluation of novel (S)-tryptamine derivatives containing an allyl group and an aryl sulfonamide unit as anticancer agents Z Guo, Y Xu, Y Peng, H ur Rashid, W Quan, P Xie, L Wu, J Jiang, L Wang, ... Bioorganic & medicinal chemistry letters 29 (9), 1133-1137, 2019 | 22 | 2019 |
| Design, synthesis, and biological evaluation of matrine derivatives possessing piperazine moiety as antitumor agents Y Xu, P Liang, H Rashid, L Wu, P Xie, H Wang, S Zhang, L Wang, J Jiang Medicinal Chemistry Research 28, 1618-1627, 2019 | 16 | 2019 |
| Design, synthesis and evaluation of novel sophoridinic imine derivatives containing conjugated planar structure as potent anticancer agents Y Xu, D Jing, R Chen, HU Rashid, J Jiang, X Liu, L Wang, P Xie Bioorganic & Medicinal Chemistry 26 (14), 4136-4144, 2018 | 16 | 2018 |
| Discovery of carbon-11 labeled sulfonamide derivative: A PET tracer for imaging brain NLRP3 inflammasome Y Xu, Y Xu, H Blevins, Y Lan, Y Liu, G Yuan, R Striar, JS Zagaroli, ... Bioorganic & medicinal chemistry letters 34, 127777, 2021 | 15 | 2021 |
| Novel indolo-sophoridinic scaffold as Topo I inhibitors: Design, synthesis and biological evaluation as anticancer agents Y Xu, L Wu, HU Rashid, D Jing, X Liang, H Wang, X Liu, J Jiang, L Wang, ... European Journal of Medicinal Chemistry 156, 479-492, 2018 | 13 | 2018 |
| Novel α, β-unsaturated sophoridinic derivatives: design, synthesis, molecular docking and anti-cancer activities Y Xu, L Wu, H Dai, M Gao, H Ur Rashid, H Wang, P Xie, X Liu, J Jiang, ... Molecules 22 (11), 1967, 2017 | 13 | 2017 |
| New modification strategy of matrine as Hsp90 inhibitors based on its specific L conformation for cancer treatment Y Xu, D Jing, D Zhao, Y Wu, L Xing, H ur Rashid, H Wang, L Wang, H Cao Bioorganic & Medicinal Chemistry 28 (4), 115305, 2020 | 11 | 2020 |
| Characteristics and kinetics of rosin pentaerythritol ester via oxidation process under ultraviolet irradiation Y Li, X Liu, Q Zhang, B Wang, C Yu, HU Rashid, Y Xu, L Ma, F Lai Molecules 23 (11), 2816, 2018 | 9 | 2018 |
| Development of sulfonamide-based NLRP3 inhibitors: Further modifications and optimization through structure-activity relationship studies Y Xu, Y Xu, H Blevins, C Guo, S Biby, XY Wang, C Wang, S Zhang European journal of medicinal chemistry 238, 114468, 2022 | 8 | 2022 |
| The NLRP3 inflammasome pathway: A review of mechanisms and inhibitors for the treatment of inflammatory diseases. Front Aging Neurosci 2022; 14: 879021 HM Blevins, Y Xu, S Biby, S Zhang | 8 | 2022 |
| A patent review of NLRP3 inhibitors to treat autoimmune diseases Y Xu, S Biby, B Kaur, S Zhang Expert Opinion on Therapeutic Patents 33 (6), 455-470, 2023 | 7 | 2023 |
| Complex Crystal Structure Determination and in vitro Anti–non–small Cell Lung Cancer Activity of Hsp90N Inhibitor SNX-2112 D Zhao, YM Xu, LQ Cao, F Yu, H Zhou, W Qin, HJ Li, CX He, L Xing, ... Frontiers in Cell and Developmental Biology 9, 650106, 2021 | 7 | 2021 |
| Characterization and discovery of a selective small-molecule modulator of mitochondrial complex I targeting a unique binding site JC Green, Y Jiang, L He, Y Xu, D Sun, T Keoprasert, C Nelson, U Oh, ... Journal of medicinal chemistry 63 (20), 11819-11830, 2020 | 6 | 2020 |
| Novel matrinic acid derivatives bearing 2‐anilinothiazole structure for non‐small cell lung cancer treatment with improved Hsp90 targeting effect Y Xu, P Zeng, H Wang, K Han, G Qiu, Y Wei, R Chen, L Wang, X Liu Drug Development Research, 2022 | 5 | 2022 |
| Novel positron emission tomography radiotracers for imaging mitochondrial complex I Y Xu, Y Xu, S Biby, P Bai, Y Liu, C Zhang, C Wang, S Zhang ACS chemical neuroscience 12 (24), 4491-4499, 2021 | 3 | 2021 |
Shijun Zhang在 vcu.edu 的电子邮件经过验证
