Asymmetry in the assembly of the RNAi enzyme complex DS Schwarz, G Hutvágner, T Du, Z Xu, N Aronin, PD Zamore Cell 115 (2), 199-208, 2003 | 4152 | 2003 |
A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA G Hutvagner, J McLachlan, AE Pasquinelli, É Bálint, T Tuschl, PD Zamore Science 293 (5531), 834-838, 2001 | 3894 | 2001 |
A microRNA in a multiple-turnover RNAi enzyme complex G Hutvagner, PD Zamore Science 297 (5589), 2056-2060, 2002 | 3025 | 2002 |
Argonaute proteins: key players in RNA silencing G Hutvagner, MJ Simard Nature reviews Molecular cell biology 9 (1), 22-32, 2008 | 1781 | 2008 |
Sequence-specific inhibition of small RNA function G Hutvágner, MJ Simard, CC Mello, PD Zamore PLoS biology 2 (4), e98, 2004 | 1006* | 2004 |
RNAi: nature abhors a double-strand G Hutvágner, PD Zamore Current opinion in genetics & development 12 (2), 225-232, 2002 | 859 | 2002 |
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways DS Schwarz, G Hutvágner, B Haley, PD Zamore Molecular cell 10 (3), 537-548, 2002 | 757 | 2002 |
Filtering of deep sequencing data reveals the existence of abundant Dicer-dependent small RNAs derived from tRNAs C Cole, A Sobala, C Lu, SR Thatcher, A Bowman, JWS Brown, PJ Green, ... Rna 15 (12), 2147-2160, 2009 | 673 | 2009 |
Principles and effects of microRNA-mediated post-transcriptional gene regulation BM Engels, G Hutvagner Oncogene 25 (46), 6163-6169, 2006 | 543 | 2006 |
Methods and compositions for enhancing the efficacy and specificity of RNA silencing PD Zamore, G Hutvágner, D Schwarz, M Simard US Patent 7,750,144, 2010 | 406 | 2010 |
Small RNAs derived from the 5′ end of tRNA can inhibit protein translation in human cells A Sobala, G Hutvagner RNA biology 10 (4), 553-563, 2013 | 335 | 2013 |
Methods and compositions for enhancing the efficacy and specificity of RNAi PD Zamore, G Hutvagner, D Schwarz, M Simard US Patent 8,309,704, 2012 | 335 | 2012 |
RNA-based therapeutics: from antisense oligonucleotides to miRNAs S Bajan, G Hutvagner Cells 9 (1), 137, 2020 | 321 | 2020 |
Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes IJ Gallagher, C Scheele, P Keller, AR Nielsen, J Remenyi, CP Fischer, ... Genome medicine 2, 1-18, 2010 | 305 | 2010 |
In vivo production of small interfering RNAS that mediate gene silencing PD Zamore, J McLachlan, G Hutvagner, A Grishok, CC Mello US Patent 7,691,995, 2010 | 302 | 2010 |
Small RNA asymmetry in RNAi: function in RISC assembly and gene regulation G Hutvagner FEBS letters 579 (26), 5850-5857, 2005 | 286 | 2005 |
Regulation of the miR-212/132 locus by MSK1 and CREB in response to neurotrophins J Remenyi, CJ Hunter, C Cole, H Ando, S Impey, CE Monk, KJ Martin, ... Biochemical Journal 428 (2), 281-291, 2010 | 259 | 2010 |
tRNA-derived fragments (tRFs): emerging new roles for an ancient RNA in the regulation of gene expression SP Keam, G Hutvagner Life 5 (4), 1638-1651, 2015 | 252 | 2015 |
Compositions for RNA interference and methods of use thereof PD Zamore, G Hutvágner, D Schwarz, G Tang, B Haley US Patent 8,729,036, 2014 | 245 | 2014 |
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells R Mudhasani, Z Zhu, G Hutvagner, CM Eischen, S Lyle, LL Hall, ... The Journal of cell biology 181 (7), 1055-1063, 2008 | 224 | 2008 |