Synthesis, debugging, and effects of synthetic chromosome consolidation: synVI and beyond LA Mitchell, A Wang, G Stracquadanio, Z Kuang, X Wang, K Yang, ... Science 355 (6329), eaaf4831, 2017 | 243 | 2017 |
Structure and mechanism of a nitrate transporter H Yan, W Huang, C Yan, X Gong, S Jiang, Y Zhao, J Wang, Y Shi Cell reports 3 (3), 716-723, 2013 | 110 | 2013 |
Pathway engineering in yeast for synthesizing the complex polyketide bikaverin M Zhao, Y Zhao, M Yao, H Iqbal, Q Hu, H Liu, B Qiao, C Li, ... Nature communications 11 (1), 6197, 2020 | 53 | 2020 |
Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions Y Zhao, C Coelho, AL Hughes, L Lazar-Stefanita, S Yang, AN Brooks, ... Cell 186 (24), 5220-5236. e16, 2023 | 47 | 2023 |
On the genetic basis of tail-loss evolution in humans and apes B Xia, W Zhang, G Zhao, X Zhang, J Bai, R Brosh, A Wudzinska, E Huang, ... Nature 626 (8001), 1042-1048, 2024 | 44 | 2024 |
CRISPR–Cas12a system in fission yeast for multiplex genomic editing and CRISPR interference Y Zhao, JD Boeke Nucleic acids research 48 (10), 5788-5798, 2020 | 36 | 2020 |
Design, construction, and functional characterization of a tRNA neochromosome in yeast D Schindler, RSK Walker, S Jiang, AN Brooks, Y Wang, CA Müller, ... Cell 186 (24), 5237-5253. e22, 2023 | 32 | 2023 |
Development of a Tightly Controlled Off Switch for Saccharomyces cerevisiae Regulated by Camphor, a Low-Cost Natural Product S Ikushima, Y Zhao, JD Boeke G3: Genes, Genomes, Genetics 5 (10), 1983-1990, 2015 | 29 | 2015 |
Dynamics of synthetic yeast chromosome evolution shaped by hierarchical chromatin organization S Zhou, Y Wu, Y Zhao, Z Zhang, L Jiang, L Liu, Y Zhang, J Tang, YJ Yuan National Science Review 10 (5), nwad073, 2023 | 22 | 2023 |
Manipulating the 3D organization of the largest synthetic yeast chromosome W Zhang, L Lazar-Stefanita, H Yamashita, MJ Shen, LA Mitchell, ... Molecular Cell 83 (23), 4424-4437. e5, 2023 | 18 | 2023 |
Systematic dissection of key factors governing recombination outcomes by GCE-SCRaMbLE H Zhang, X Fu, X Gong, Y Wang, H Zhang, Y Zhao, Y Shen Nature Communications 13 (1), 5836, 2022 | 17 | 2022 |
Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function J Luo, LA Vale-Silva, AR Raghavan, G Mercy, J Heldrich, X Sun, MK Li, ... Cell Genomics 3 (11), 2023 | 16 | 2023 |
Construction of Designer Selectable Marker Deletions with a CRISPR-Cas9 Toolbox in Schizosaccharomyces pombe and New Design of Common Entry Vectors Y Zhao, JD Boeke G3: Genes, Genomes, Genetics 8 (3), 789-796, 2018 | 15 | 2018 |
Synthetic yeast chromosome XI design provides a testbed for the study of extrachromosomal circular DNA dynamics BA Blount, X Lu, MRM Driessen, D Jovicevic, MI Sanchez, K Ciurkot, ... Cell Genomics 3 (11), 2023 | 13 | 2023 |
Context-dependent neocentromere activity in synthetic yeast chromosome VIII S Lauer, J Luo, L Lazar-Stefanita, W Zhang, LH McCulloch, V Fanfani, ... Cell Genomics 3 (11), 2023 | 12 | 2023 |
CREEPY: CRISPR-mediated editing of synthetic episomes in yeast Y Zhao, C Coelho, S Lauer, M Majewski, JM Laurent, R Brosh, JD Boeke Nucleic acids research 51 (13), e72-e72, 2023 | 6 | 2023 |
Ccp1-Ndc80 switch at the N terminus of CENP-T regulates kinetochore assembly Q Dong, X Liu, X Wang, Y Zhao, Y Chen, F Li Proceedings of the National Academy of Sciences 118 (48), e2104459118, 2021 | 5 | 2021 |
Build-A-Genome and the “awesome power of undergraduates” JD Boeke, JS Bader, L Basta, Y Cai, C Chapman, E Cooper, J Dymond, ... Genetics 227 (4), 2024 | | 2024 |