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Dimitrios Mastellos
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Complement and tissue factor–enriched neutrophil extracellular traps are key drivers in COVID-19 immunothrombosis
P Skendros, A Mitsios, A Chrysanthopoulou, DC Mastellos, S Metallidis, ...
The Journal of clinical investigation 130 (11), 6151-6157, 2020
6932020
Complement as a target in COVID-19?
AM Risitano, DC Mastellos, M Huber-Lang, D Yancopoulou, C Garlanda, ...
Nature Reviews Immunology 20 (6), 343-344, 2020
5502020
A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways
K Ritis, M Doumas, D Mastellos, A Micheli, S Giaglis, P Magotti, S Rafail, ...
The Journal of Immunology 177 (7), 4794-4802, 2006
5482006
The proinflammatory mediators C3a and C5a are essential for liver regeneration
CW Strey, M Markiewski, D Mastellos, R Tudoran, LA Spruce, ...
The Journal of experimental medicine 198 (6), 913-923, 2003
5212003
Complement component C3–The “Swiss Army Knife” of innate immunity and host defense
D Ricklin, ES Reis, DC Mastellos, P Gros, JD Lambris
Immunological reviews 274 (1), 33-58, 2016
5112016
Novel mechanisms and functions of complement
G Hajishengallis, ES Reis, DC Mastellos, D Ricklin, JD Lambris
Nature immunology 18 (12), 1288-1298, 2017
4422017
The renaissance of complement therapeutics
D Ricklin, DC Mastellos, ES Reis, JD Lambris
Nature Reviews Nephrology 14 (1), 26-47, 2018
3582018
New insights into the immune functions of complement
ES Reis, DC Mastellos, G Hajishengallis, JD Lambris
Nature Reviews Immunology 19 (8), 503-516, 2019
3522019
Complement in cancer: untangling an intricate relationship
ES Reis, DC Mastellos, D Ricklin, A Mantovani, JD Lambris
Nature Reviews Immunology 18 (1), 5-18, 2018
3512018
A novel role of complement: mice deficient in the fifth component of complement (C5) exhibit impaired liver regeneration
D Mastellos, JC Papadimitriou, S Franchini, PA Tsonis, JD Lambris
The Journal of Immunology 166 (4), 2479-2486, 2001
3082001
The first case of COVID-19 treated with the complement C3 inhibitor AMY-101
S Mastaglio, A Ruggeri, AM Risitano, P Angelillo, D Yancopoulou, ...
Clinical immunology 215, 108450, 2020
2982020
Increased C5a receptor expression in sepsis
NC Riedemann, RF Guo, TA Neff, IJ Laudes, KA Keller, VJ Sarma, ...
The Journal of clinical investigation 110 (1), 101-108, 2002
2972002
Clinical promise of next-generation complement therapeutics
DC Mastellos, D Ricklin, JD Lambris
Nature reviews Drug discovery 18 (9), 707-729, 2019
2882019
Functional receptor for C3a anaphylatoxin is expressed by normal hematopoietic stem/progenitor cells, and C3a enhances their homing-related responses to SDF-1
R Reca, D Mastellos, M Majka, L Marquez, J Ratajczak, S Franchini, ...
Blood, The Journal of the American Society of Hematology 101 (10), 3784-3793, 2003
2662003
Complement C3 vs C5 inhibition in severe COVID-19: Early clinical findings reveal differential biological efficacy
DC Mastellos, BGPP da Silva, BAL Fonseca, NP Fonseca, ...
Clinical Immunology 220, 108598, 2020
2272020
Compstatin: a C3‐targeted complement inhibitor reaching its prime for bedside intervention
DC Mastellos, D Yancopoulou, P Kokkinos, M Huber‐Lang, ...
European journal of clinical investigation 45 (4), 423-440, 2015
2252015
Protection of innate immunity by C5aR antagonist in septic mice
MS Huber‐Lang, NC Riedeman, JV Sarma, EM Younkin, SR McGuire, ...
Wiley Periodicals, Inc., 2002
2122002
Complement: more than a ‘guard’against invading pathogens?
D Mastellos, JD Lambris
TRENDS in Immunology 23 (10), 485-491, 2002
2022002
C3a and C3b activation products of the third component of complement (C3) are critical for normal liver recovery after toxic injury
MM Markiewski, D Mastellos, R Tudoran, RA DeAngelis, CW Strey, ...
The Journal of Immunology 173 (2), 747-754, 2004
1922004
Phylogenetic aspects of the complement system
IK Zarkadis, D Mastellos, JD Lambris
Developmental & Comparative Immunology 25 (8-9), 745-762, 2001
1762001
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