Single-cell functional and chemosensitive profiling of combinatorial colorectal therapy in zebrafish xenografts R Fior, V Póvoa, RV Mendes, T Carvalho, A Gomes, N Figueiredo, ... Proceedings of the National Academy of Sciences 114 (39), E8234-E8243, 2017 | 291 | 2017 |
A novel hes5/hes6 circuitry of negative regulation controls Notch activity during neurogenesis R Fior, D Henrique Developmental biology 281 (2), 318-333, 2005 | 138 | 2005 |
The differentiation and movement of presomitic mesoderm progenitor cells are controlled by Mesogenin 1 R Fior, AA Maxwell, TP Ma, A Vezzaro, CB Moens, SL Amacher, J Lewis, ... Development 139 (24), 4656-4665, 2012 | 79 | 2012 |
Platinum-Triggered Bond-Cleavage of Pentynoyl Amide and N-Propargyl Handles for Drug-Activation BL Oliveira, BJ Stenton, VB Unnikrishnan, CR de Almeida, J Conde, ... Journal of the American Chemical Society 142 (24), 10869-10880, 2020 | 75 | 2020 |
Zebrafish avatars towards personalized medicine—a comparative review between avatar models B Costa, MF Estrada, RV Mendes, R Fior Cells 9 (2), 293, 2020 | 70 | 2020 |
Zebrafish xenografts as a fast screening platform for bevacizumab cancer therapy C Rebelo de Almeida, RV Mendes, A Pezzarossa, J Gago, C Carvalho, ... Communications biology 3 (1), 299, 2020 | 51 | 2020 |
Innate immune evasion revealed in a colorectal zebrafish xenograft model V Póvoa, C Rebelo de Almeida, M Maia-Gil, D Sobral, M Domingues, ... Nature communications 12 (1), 1156, 2021 | 49 | 2021 |
A novel reporter of notch signalling indicates regulated and random Notch activation during vertebrate neurogenesis F Vilas-Boas, R Fior, JR Swedlow, KG Storey, D Henrique BMC biology 9, 1-16, 2011 | 49 | 2011 |
Developments in zebrafish avatars as radiotherapy sensitivity reporters—towards personalized medicine B Costa, S Ferreira, V Póvoa, MJ Cardoso, S Vieira, J Stroom, P Fidalgo, ... EBioMedicine 51, 2020 | 46 | 2020 |
" Notch-Off": a perspective on the termination of Notch signalling. R Fior, D Henrique International Journal of Developmental Biology 53, 2009 | 36 | 2009 |
The Core-Clock Gene NR1D1 Impacts Cell Motility In Vitro and Invasiveness in a Zebrafish Xenograft Colon Cancer Model A Basti, R Fior, M Yalҫin, V Póvoa, R Astaburuaga, Y Li, J Naderi, ... Cancers 12 (4), 853, 2020 | 26 | 2020 |
The histone acetyltransferase hMOF promotes vascular invasion in hepatocellular carcinoma N Poté, J Cros, S Laouirem, J Raffenne, M Negrão, M Albuquerque, ... Liver International 40 (4), 956-967, 2020 | 25 | 2020 |
Identification and expression analysis of two novel members of the Mesp family in zebrafish SJ Cutty, R Fior, PM Henriques, FC Wardle Int. J. Dev. Biol. 56, 285-294, 2012 | 23 | 2012 |
Generation of zebrafish larval xenografts and tumor behavior analysis M Martinez-Lopez, V Póvoa, R Fior JoVE (Journal of Visualized Experiments), e62373, 2021 | 22 | 2021 |
Zebrafish xenografts unveil sensitivity to olaparib beyond BRCA status AB Varanda, A Martins-Logrado, M Godinho Ferreira, R Fior Cancers 12 (7), 1769, 2020 | 20 | 2020 |
Object detection for automatic cancer cell counting in zebrafish xenografts C Albuquerque, L Vanneschi, R Henriques, M Castelli, V Póvoa, R Fior, ... Plos one 16 (11), e0260609, 2021 | 14 | 2021 |
Molecular and cell biology of cancer R Fior, R Zilhão Springer International Publishing, 2019 | 12 | 2019 |
Establishment of pancreatobiliary cancer zebrafish avatars for chemotherapy screening M Tavares Barroso, B Costa, C Rebelo de Almeida, M Castillo Martin, ... Cells 10 (8), 2077, 2021 | 10 | 2021 |
Zebrafish Patient‐Derived Avatars from Digestive Cancers for Anti‐cancer Therapy Screening B Costa, MF Estrada, MT Barroso, R Fior Current Protocols 2 (4), e415, 2022 | 7 | 2022 |
Predictive and therapeutic implications of a novel PLCγ1/SHP2-driven mechanism of cetuximab resistance in metastatic colorectal cancer R Cruz-Duarte, C Rebelo de Almeida, M Negrão, A Fernandes, ... Clinical Cancer Research 28 (6), 1203-1216, 2022 | 6 | 2022 |