| Biologically inactive leptin and early-onset extreme obesity M Wabitsch, JB Funcke, B Lennerz, U Kuhnle-Krahl, G Lahr, KM Debatin, ... New England Journal of Medicine 372 (1), 48-54, 2015 | 243 | 2015 |
| Beyond adiponectin and leptin: adipose tissue-derived mediators of inter-organ communication JB Funcke, PE Scherer Journal of lipid research 60 (10), 1648-1697, 2019 | 239 | 2019 |
| Extracellular vesicle-based interorgan transport of mitochondria from energetically stressed adipocytes C Crewe, JB Funcke, S Li, N Joffin, CM Gliniak, AL Ghaben, YA An, ... Cell metabolism 33 (9), 1853-1868. e11, 2021 | 193 | 2021 |
| miR-146a-mediated suppression of the inflammatory response in human adipocytes J Roos, E Enlund, JB Funcke, D Tews, K Holzmann, KM Debatin, ... Scientific reports 6 (1), 38339, 2016 | 110 | 2016 |
| Monogenic forms of childhood obesity due to mutations in the leptin gene JB Funcke, J von Schnurbein, B Lennerz, G Lahr, KM Debatin, ... Molecular and cellular pediatrics 1, 1-8, 2014 | 109 | 2014 |
| Severe early-onset obesity due to bioinactive leptin caused by a p. N103K mutation in the leptin gene M Wabitsch, JB Funcke, J von Schnurbein, F Denzer, G Lahr, I Mazen, ... The Journal of Clinical Endocrinology & Metabolism 100 (9), 3227-3230, 2015 | 87 | 2015 |
| Functional and phenotypic characteristics of human leptin receptor mutations A Nunziata, JB Funcke, G Borck, J von Schnurbein, S Brandt, B Lennerz, ... Journal of the Endocrine Society 3 (1), 27-41, 2019 | 75 | 2019 |
| Early childhood BMI trajectories in monogenic obesity due to leptin, leptin receptor, and melanocortin 4 receptor deficiency K Kohlsdorf, A Nunziata, JB Funcke, S Brandt, J von Schnurbein, ... International Journal of Obesity 42 (9), 1602-1609, 2018 | 57 | 2018 |
| Adipocyte iron levels impinge on a fat-gut crosstalk to regulate intestinal lipid absorption and mediate protection from obesity Z Zhang, JB Funcke, Z Zi, S Zhao, LG Straub, Y Zhu, Q Zhu, C Crewe, ... Cell metabolism 33 (8), 1624-1639. e9, 2021 | 55 | 2021 |
| Dysregulation of amyloid precursor protein impairs adipose tissue mitochondrial function and promotes obesity YA An, C Crewe, IW Asterholm, K Sun, S Chen, F Zhang, M Shao, ... Nature metabolism 1 (12), 1243-1257, 2019 | 43 | 2019 |
| Elevated UCP1 levels are sufficient to improve glucose uptake in human white adipocytes D Tews, T Pula, JB Funcke, M Jastroch, M Keuper, KM Debatin, ... Redox biology 26, 101286, 2019 | 41 | 2019 |
| Resveratrol suppresses PAI-1 gene expression in a human in vitro model of inflamed adipose tissue I Zagotta, EY Dimova, JB Funcke, M Wabitsch, T Kietzmann, ... Oxidative medicine and cellular longevity 2013, 2013 | 36 | 2013 |
| Trail (TNF-related apoptosis-inducing ligand) induces an inflammatory response in human adipocytes V Zoller, JB Funcke, J Roos, M Dahlhaus, M Abd El Hay, K Holzmann, ... Scientific Reports 7 (1), 5691, 2017 | 35 | 2017 |
| The mitochondrial dicarboxylate carrier prevents hepatic lipotoxicity by inhibiting white adipocyte lipolysis YA An, S Chen, Y Deng, ZV Wang, JB Funcke, M Shah, B Shan, ... Journal of hepatology 75 (2), 387-399, 2021 | 34 | 2021 |
| TRAIL (TNF-related apoptosis-inducing ligand) inhibits human adipocyte differentiation via caspase-mediated downregulation of adipogenic transcription factors V Zoller, JB Funcke, M Keuper, M Abd El Hay, KM Debatin, M Wabitsch, ... Cell death & disease 7 (10), e2412-e2412, 2016 | 33 | 2016 |
| Estimated prevalence of potentially damaging variants in the leptin gene A Nunziata, G Borck, JB Funcke, K Kohlsdorf, S Brandt, A Hinney, ... Molecular and cellular pediatrics 4, 1-5, 2017 | 28 | 2017 |
| Measurement of immunofunctional leptin to detect and monitor patients with functional leptin deficiency M Wabitsch, L Pridzun, M Ranke, J von Schnurbein, A Moss, S Brandt, ... European journal of endocrinology 176 (3), 315-322, 2017 | 28 | 2017 |
| miR-146a regulates insulin sensitivity via NPR3 J Roos, M Dahlhaus, JB Funcke, M Kustermann, G Strauss, ... Cellular and Molecular Life Sciences 78, 2987-3003, 2021 | 25 | 2021 |
| TNF-related apoptosis-inducing ligand promotes human preadipocyte proliferation via ERK1/2 activation JB Funcke, V Zoller, M Abd El Hay, KM Debatin, M Wabitsch, ... The FASEB Journal 29 (7), 3065, 2015 | 21 | 2015 |
| Adipose tissue macrophages exert systemic metabolic control by manipulating local iron concentrations N Joffin, CM Gliniak, JB Funcke, VA Paschoal, C Crewe, S Chen, ... Nature Metabolism 4 (11), 1474-1494, 2022 | 16 | 2022 |
