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Melat Gebru
Melat Gebru
Calico Life Sciences
在 calicolabs.com 的电子邮件经过验证
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An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure
Y Takahashi, H He, Z Tang, T Hattori, Y Liu, MM Young, JM Serfass, ...
Nature communications 9 (1), 2855, 2018
3252018
Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis
Z Tang, Y Takahashi, C Chen, Y Liu, H He, N Tsotakos, JM Serfass, ...
Cell Death & Differentiation 24 (12), 2127-2138, 2017
792017
Targeted inhibition of ULK1 promotes apoptosis and suppresses tumor growth and metastasis in neuroblastoma
CM Dower, N Bhat, MT Gebru, L Chen, CA Wills, BA Miller, HG Wang
Molecular cancer therapeutics 17 (11), 2365-2376, 2018
742018
Therapeutic targeting of FLT3 and associated drug resistance in acute myeloid leukemia
MT Gebru, HG Wang
Journal of Hematology & Oncology 13 (1), 155, 2020
632020
Glucocorticoids enhance the antileukemic activity of FLT3 inhibitors in FLT3-mutant acute myeloid leukemia
MT Gebru, JM Atkinson, MM Young, L Zhang, Z Tang, Z Liu, P Lu, ...
Blood, The Journal of the American Society of Hematology 136 (9), 1067-1079, 2020
292020
Time-resolved FRET and NMR analyses reveal selective binding of peptides containing the LC3-interacting region to ATG8 family proteins
JM Atkinson, Y Ye, MT Gebru, Q Liu, S Zhou, MM Young, Y Takahashi, ...
Journal of Biological Chemistry 294 (38), 14033-14042, 2019
182019
Data-driven math model of FLT3-ITD acute myeloid leukemia reveals potential therapeutic targets
DJ Wooten, M Gebru, HG Wang, R Albert
Journal of personalized medicine 11 (3), 193, 2021
102021
An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure. Nat Commun 9: 2855
Y Takahashi, H He, Z Tang, T Hattori, Y Liu, MM Young, JM Serfass, ...
72018
Abstract B017: Loss of UXS1 selectively kills KEAP1 mutant cancer cell lines by depleting pyrimidines and inducing replication stress
T Hoffman, M Gebru, A Boudreau, F Han, K Foster-Duke, J Gajda, N Vu, ...
Molecular Cancer Therapeutics 23 (6_Supplement), B017-B017, 2024
2024
Glucocorticoids act synergistically with FLT3 inhibitors to enhance cell death in FLT3 mutant acute myeloid leukemia
MT Gebru, HG Wang, J Xavier
Cancer Research 80 (16_Supplement), 637-637, 2020
2020
Mechanism of Drug Tolerance in FLT3 Mutant Acute Myeloid Leukemia
M Gebru
2020
A luciferase-based assay identifies niclosamide derivatives antagonizing Mcl-1 through post-translational down-regulation
Q Liu, JM Atkinson, MT Gebru, K Clements, GL Moldovan, HG Wang
bioRxiv, 665505, 2019
2019
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