An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure Y Takahashi, H He, Z Tang, T Hattori, Y Liu, MM Young, JM Serfass, ... Nature communications 9 (1), 2855, 2018 | 325 | 2018 |
Atg2A/B deficiency switches cytoprotective autophagy to non-canonical caspase-8 activation and apoptosis Z Tang, Y Takahashi, C Chen, Y Liu, H He, N Tsotakos, JM Serfass, ... Cell Death & Differentiation 24 (12), 2127-2138, 2017 | 79 | 2017 |
Targeted inhibition of ULK1 promotes apoptosis and suppresses tumor growth and metastasis in neuroblastoma CM Dower, N Bhat, MT Gebru, L Chen, CA Wills, BA Miller, HG Wang Molecular cancer therapeutics 17 (11), 2365-2376, 2018 | 74 | 2018 |
Therapeutic targeting of FLT3 and associated drug resistance in acute myeloid leukemia MT Gebru, HG Wang Journal of Hematology & Oncology 13 (1), 155, 2020 | 63 | 2020 |
Glucocorticoids enhance the antileukemic activity of FLT3 inhibitors in FLT3-mutant acute myeloid leukemia MT Gebru, JM Atkinson, MM Young, L Zhang, Z Tang, Z Liu, P Lu, ... Blood, The Journal of the American Society of Hematology 136 (9), 1067-1079, 2020 | 29 | 2020 |
Time-resolved FRET and NMR analyses reveal selective binding of peptides containing the LC3-interacting region to ATG8 family proteins JM Atkinson, Y Ye, MT Gebru, Q Liu, S Zhou, MM Young, Y Takahashi, ... Journal of Biological Chemistry 294 (38), 14033-14042, 2019 | 18 | 2019 |
Data-driven math model of FLT3-ITD acute myeloid leukemia reveals potential therapeutic targets DJ Wooten, M Gebru, HG Wang, R Albert Journal of personalized medicine 11 (3), 193, 2021 | 10 | 2021 |
An autophagy assay reveals the ESCRT-III component CHMP2A as a regulator of phagophore closure. Nat Commun 9: 2855 Y Takahashi, H He, Z Tang, T Hattori, Y Liu, MM Young, JM Serfass, ... | 7 | 2018 |
Abstract B017: Loss of UXS1 selectively kills KEAP1 mutant cancer cell lines by depleting pyrimidines and inducing replication stress T Hoffman, M Gebru, A Boudreau, F Han, K Foster-Duke, J Gajda, N Vu, ... Molecular Cancer Therapeutics 23 (6_Supplement), B017-B017, 2024 | | 2024 |
Glucocorticoids act synergistically with FLT3 inhibitors to enhance cell death in FLT3 mutant acute myeloid leukemia MT Gebru, HG Wang, J Xavier Cancer Research 80 (16_Supplement), 637-637, 2020 | | 2020 |
Mechanism of Drug Tolerance in FLT3 Mutant Acute Myeloid Leukemia M Gebru | | 2020 |
A luciferase-based assay identifies niclosamide derivatives antagonizing Mcl-1 through post-translational down-regulation Q Liu, JM Atkinson, MT Gebru, K Clements, GL Moldovan, HG Wang bioRxiv, 665505, 2019 | | 2019 |