| Quantitative analysis of NAD synthesis-breakdown fluxes L Liu, X Su, WJ Quinn, S Hui, K Krukenberg, DW Frederick, P Redpath, ... Cell metabolism 27 (5), 1067-1080. e5, 2018 | 455 | 2018 |
| Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle DW Frederick, E Loro, L Liu, A Davila, K Chellappa, IM Silverman, ... Cell metabolism 24 (2), 269-282, 2016 | 340 | 2016 |
| CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels CCS Chini, TR Peclat, GM Warner, S Kashyap, JM Espindola-Netto, ... Nature metabolism 2 (11), 1284-1304, 2020 | 208 | 2020 |
| Nicotinamide adenine dinucleotide is transported into mammalian mitochondria A Davila, L Liu, K Chellappa, P Redpath, E Nakamaru-Ogiso, LM Paolella, ... Elife 7, e33246, 2018 | 146 | 2018 |
| Soybean oil is more obesogenic and diabetogenic than coconut oil and fructose in mouse: potential role for the liver P Deol, JR Evans, J Dhahbi, K Chellappa, DS Han, S Spindler, FM Sladek PloS one 10 (7), e0132672, 2015 | 140 | 2015 |
| A microbiome-dependent gut–brain pathway regulates motivation for exercise L Dohnalová, P Lundgren, JRE Carty, N Goldstein, SL Wenski, ... Nature 612 (7941), 739-747, 2022 | 129 | 2022 |
| Age-related NAD+ decline MR McReynolds, K Chellappa, JA Baur Experimental gerontology 134, 110888, 2020 | 113 | 2020 |
| Phosphorylation of a conserved serine in the deoxyribonucleic acid binding domain of nuclear receptors alters intracellular localization K Sun, V Montana, K Chellappa, Y Brelivet, D Moras, Y Maeda, V Parpura, ... Molecular endocrinology 21 (6), 1297-1311, 2007 | 109 | 2007 |
| Nicotinamide adenine dinucleotide biosynthesis promotes liver regeneration S Mukherjee, K Chellappa, A Moffitt, J Ndungu, RW Dellinger, JG Davis, ... Hepatology 65 (2), 616-630, 2017 | 108 | 2017 |
| Src tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer K Chellappa, L Jankova, JM Schnabl, S Pan, Y Brelivet, CLS Fung, ... Proceedings of the National Academy of Sciences 109 (7), 2302-2307, 2012 | 94 | 2012 |
| Opposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer K Chellappa, P Deol, JR Evans, LM Vuong, G Chen, N Briançon, ... Elife 5, e10903, 2016 | 78 | 2016 |
| NAD+ flux is maintained in aged mice despite lower tissue concentrations MR McReynolds, K Chellappa, E Chiles, C Jankowski, Y Shen, L Chen, ... Cell systems 12 (12), 1160-1172. e4, 2021 | 64 | 2021 |
| Differential effects of hepatocyte nuclear factor 4α isoforms on tumor growth and T-cell factor 4/AP-1 interactions in human colorectal cancer cells LM Vuong, K Chellappa, JM Dhahbi, JR Deans, B Fang, E Bolotin, ... Molecular and Cellular Biology 35 (20), 3471-3490, 2015 | 63 | 2015 |
| Hypothalamic mTORC2 is essential for metabolic health and longevity K Chellappa, JA Brinkman, S Mukherjee, M Morrison, MI Alotaibi, ... Aging Cell 18 (5), e13014, 2019 | 56 | 2019 |
| NAD precursors cycle between host tissues and the gut microbiome K Chellappa, MR McReynolds, W Lu, X Zeng, M Makarov, F Hayat, ... Cell metabolism 34 (12), 1947-1959. e5, 2022 | 48 | 2022 |
| HNF4α: a new biomarker in colon cancer? K Chellappa, GR Robertson, FM Sladek Biomarkers in medicine 6 (3), 297-300, 2012 | 41 | 2012 |
| The leptin sensitizer celastrol reduces age‐associated obesity and modulates behavioral rhythms K Chellappa, IJ Perron, N Naidoo, JA Baur Aging cell 18 (3), e12874, 2019 | 39 | 2019 |
| NAD+ precursor supplementation prevents mtRNA/RIG-I-dependent inflammation during kidney injury T Doke, S Mukherjee, D Mukhi, P Dhillon, A Abedini, JG Davis, ... Nature metabolism 5 (3), 414-430, 2023 | 32 | 2023 |
| Nuclear receptor HNF4α binding sequences are widespread in Alu repeats E Bolotin, K Chellappa, W Hwang-Verslues, JM Schnabl, C Yang, ... BMC genomics 12, 1-15, 2011 | 27 | 2011 |
| Rapamycin maintains NAD+/NADH redox homeostasis in muscle cells Z Zhang, HN Xu, S Li, A Davila Jr, K Chellappa, JG Davis, Y Guan, ... Aging (albany NY) 12 (18), 17786, 2020 | 24 | 2020 |
