Dynamic landscape and regulation of RNA editing in mammals MH Tan, Q Li, R Shanmugam, R Piskol, J Kohler, AN Young, KI Liu, ... Nature 550 (7675), 249-254, 2017 | 554 | 2017 |
Accurate identification of human Alu and non-Alu RNA editing sites G Ramaswami, W Lin, R Piskol, MH Tan, C Davis, JB Li Nature methods 9 (6), 579-581, 2012 | 382 | 2012 |
Comment on "Widespread RNA and DNA sequence differences in the human transcriptome" JBL W Lin, R Piskol, MH Tan Science 335 (6074), 1302, 2012 | 246* | 2012 |
A chemical-inducible CRISPR–Cas9 system for rapid control of genome editing KI Liu, MNB Ramli, CWA Woo, Y Wang, T Zhao, X Zhang, GRD Yim, ... Nature chemical biology 12 (11), 980-987, 2016 | 221 | 2016 |
Precise gene deletion and replacement using the CRISPR/Cas9 system in human cells HS Zheng Q, Cai X, Tan MH, Schaffert S, Arnold CP, Gong X, Chen CZ Biotechniques 57 (3), 115-124, 2014 | 196 | 2014 |
High-throughput identification of transcription start sites, conserved promoter motifs and predicted regulons PT McGrath, H Lee, L Zhang, AA Iniesta, AK Hottes, MH Tan, NJ Hillson, ... Nature biotechnology 25 (5), 584-592, 2007 | 181 | 2007 |
RNA sequencing reveals a diverse and dynamic repertoire of the Xenopus tropicalis transcriptome over development MH Tan, KF Au, AL Yablonovitch, AE Wills, J Chuang, JC Baker, ... Genome research 23 (1), 201-216, 2013 | 156 | 2013 |
Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells YJ Choi, CP Lin, D Risso, S Chen, TA Kim, MH Tan, JB Li, Y Wu, C Chen, ... Science 355 (6325), eaag1927, 2017 | 153 | 2017 |
An engineered CRISPR-Cas12a variant and DNA-RNA hybrid guides enable robust and rapid COVID-19 testing KH Ooi, MM Liu, JWD Tay, SY Teo, P Kaewsapsak, S Jin, CK Lee, J Hou, ... Nature communications 12 (1), 1739, 2021 | 147 | 2021 |
Systematic evaluation of CRISPR-Cas systems reveals design principles for genome editing in human cells Y Wang, KI Liu, NAB Sutrisnoh, H Srinivasan, J Zhang, J Li, F Zhang, ... Genome biology 19, 1-16, 2018 | 92 | 2018 |
Determination of isoform-specific RNA structure with nanopore long reads JGA Aw, SW Lim, JX Wang, FRP Lambert, WT Tan, Y Shen, Y Zhang, ... Nature biotechnology 39 (3), 336-346, 2021 | 91 | 2021 |
An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation MH Tan, JB Kozdon, X Shen, L Shapiro, HH McAdams Proceedings of the National Academy of Sciences 107 (44), 18985-18990, 2010 | 91 | 2010 |
Maternally and zygotically provided Cdx2 have novel and critical roles for early development of the mouse embryo A Jedrusik, AW Bruce, MH Tan, DE Leong, M Skamagki, M Yao, ... Developmental biology 344 (1), 66-78, 2010 | 91 | 2010 |
An Oct4‐Sall4‐Nanog network controls developmental progression in the pre‐implantation mouse embryo MH Tan, KF Au, DE Leong, K Foygel, WH Wong, MWM Yao Molecular systems biology 9 (1), 632, 2013 | 81 | 2013 |
Allelic expression of deleterious protein-coding variants across human tissues KR Kukurba, R Zhang, X Li, KS Smith, DA Knowles, M How Tan, R Piskol, ... PLoS genetics 10 (5), e1004304, 2014 | 73 | 2014 |
An Expanded Synthetic Biology Toolkit for Gene Expression Control in Acetobacteraceae MY Teh, KH Ooi, SX Danny Teo, ME Bin Mansoor, WZ Shaun Lim, ... ACS synthetic biology 8 (4), 708-723, 2019 | 62 | 2019 |
A human expression system based on HEK293 for the stable production of recombinant erythropoietin CL Chin, JB Goh, H Srinivasan, KI Liu, A Gowher, R Shanmugam, HL Lim, ... Scientific reports 9 (1), 16768, 2019 | 59 | 2019 |
Direct identification of A-to-I editing sites with nanopore native RNA sequencing TA Nguyen, JWJ Heng, P Kaewsapsak, EPL Kok, D Stanojević, H Liu, ... Nature methods 19 (7), 833-844, 2022 | 58 | 2022 |
Discovery and engineering of a 1-butanol biosensor in Saccharomyces cerevisiae S Shi, YW Choi, H Zhao, MH Tan, EL Ang Bioresource technology 245, 1343-1351, 2017 | 56 | 2017 |
SRSF9 selectively represses ADAR2-mediated editing of brain-specific sites in primates R Shanmugam, F Zhang, H Srinivasan, JL Charles Richard, KI Liu, ... Nucleic acids research 46 (14), 7379-7395, 2018 | 26 | 2018 |