Multiple roles of APC and its therapeutic implications in colorectal cancer L Zhang, JW Shay Journal Of The National Cancer Institute 109 (8), djw332, 2017 | 404 | 2017 |
Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer EJ Faivre, KF McDaniel, DH Albert, SR Mantena, JP Plotnik, D Wilcox, ... Nature, 1-5, 2020 | 320 | 2020 |
Acquired resistance to BET-PROTACs (proteolysis-targeting chimeras) caused by genomic alterations in core components of E3 ligase complexes L Zhang, B Riley-Gillis, P Vijay, Y Shen Molecular cancer therapeutics 18 (7), 1302-1311, 2019 | 242 | 2019 |
NOVA1 regulates hTERT splicing and cell growth in non-small cell lung cancer AT Ludlow, MS Wong, JD Robin, K Batten, L Yuan, TP Lai, N Dahlson, ... Nature Communications 9 (1), 3112, 2018 | 80 | 2018 |
Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer JKDBJWS Lu Zhang, Panayotis C. Theodoropoulos, Ugur Eskiocak, Wentian Wang ... Science Translational Medicine 8 (361), 2016 | 74 | 2016 |
Radiation promotes colorectal cancer initiation and progression by inducing senescence-associated inflammatory responses SB Kim, RG Bozeman, A Kaisani, W Kim, L Zhang, JA Richardson, ... Oncogene, 2015 | 43 | 2015 |
Cholesterol Depletion by TASIN-1 Induces Apoptotic Cell Death through the ER Stress/ROS/JNK Signaling in Colon Cancer Cells L Zhang, SB Kim, K Luitel, JW Shay Molecular Cancer Therapeutics, molcanther. 0887.2017, 2018 | 30 | 2018 |
Exome sequencing of normal and isogenic transformed human colonic epithelial cells (HCECs) reveals novel genes potentially involved in the early stages of colorectal tumorigenesis L Zhang, SB Kim, G Jia, A Buhmeida, A Dallol, WE Wright, AJ Fornace, ... BMC genomics 16 (1), S8, 2015 | 30 | 2015 |
Identification of novel driver tumor suppressors through functional interrogation of putative passenger mutations in colorectal cancer L Zhang, K Komurov, WE Wright, JW Shay International Journal of Cancer 132 (3), 732-737, 2013 | 26 | 2013 |
Inhibition of microRNA-31-5p protects human colonic epithelial cells against ionizing radiation SB Kim, L Zhang, S Barron, JW Shay Life Sciences in Space Research 1, 67-73, 2014 | 24 | 2014 |
Design and Synthesis of TASIN Analogues Specifically Targeting Colorectal Cancer Cell Lines with Mutant Adenomatous Polyposis Coli (APC) W Wang, L Zhang, L Morlock, NS Williams, JW Shay, JK De Brabander Journal of medicinal chemistry, 2019 | 18 | 2019 |
Mitigation of radiation-induced damage by targeting egfr in noncancerous human epithelial cells SB Kim, P Ly, A Kaisani, L Zhang, WE Wright, JW Shay Radiation research 180 (3), 259-267, 2013 | 18 | 2013 |
Truncated APC Mutation Induces Asef Activated Golgi Fragmentation SB Kim, L Zhang, J Yoon, J Lee, J Min, W Li, NV Grishin, YA Moon, ... Molecular and cellular biology, MCB. 00135-18, 2018 | 16 | 2018 |
Oxygen and Silicon Ion Particles Induce Neoplastic Transformation in Human Colonic Epithelial Cells SB Kim, L Zhang, JW Shay Gravitational and Space Research 2 (1), 2014 | 1 | 2014 |
Therapeutic targeting truncated adenomatous polyposis coli (APC) proteins for the selective killing of colorectal cancer cells L Zhang, SB Kim, U Eskiocak, B Posner, P Das, WE Wright, ... BMC Genomics 15 (S2), O3, 2014 | 1 | 2014 |