Development of selective inhibitors of phosphatidylinositol 3-kinase C2α WT Lo, H Belabed, M Kücükdisli, J Metag, Y Roske, P Prokofeva, ... Nature chemical biology 19 (1), 18-27, 2023 | 16 | 2023 |
Tacrine-xanomeline and tacrine-iperoxo hybrid ligands: Synthesis and biological evaluation at acetylcholinesterase and M1 muscarinic acetylcholine receptors M Maspero, D Volpato, D Cirillo, NY Chen, R Messerer, C Sotriffer, ... Bioorganic chemistry 96, 103633, 2020 | 16 | 2020 |
Structure‐Activity‐Relationship‐Aided Design and Synthesis of xCT Antiporter Inhibitors D Cirillo, S Sarowar, PØ Enger, HR Bjørsvik ChemMedChem 16 (17), 2650-2668, 2021 | 7 | 2021 |
Isoform-selective targeting of PI3K: time to consider new opportunities? D Cirillo, M Diceglie, M Nazaré Trends in Pharmacological Sciences, 2023 | 6 | 2023 |
Functionalization of the Imidazole Backbone by Means of a Tailored and Optimized Oxidative Heck Cross‐Coupling D Cirillo, F Angelucci, HR Bjørsvik Advanced Synthesis & Catalysis 362 (22), 5079-5092, 2020 | 6 | 2020 |
The styryl benzoic acid derivative DC10 potentiates radiotherapy by targeting the xCT-glutathione Axis S Sarowar, D Cirillo, P Játiva, MH Nilsen, SMA Otragane, J Heggdal, ... Frontiers in Oncology 12, 786739, 2022 | 4 | 2022 |
Structural Basis for Highly Selective Class II Alpha Phosphoinositide-3-Kinase Inhibition M Kücükdisli, H Bel-Abed, D Cirillo, WT Lo, NL Efrém, A Horatscheck, ... Journal of Medicinal Chemistry 66 (20), 14278-14302, 2023 | 2 | 2023 |
Novel Xanomeline-containing bitopic ligands of muscarinic acetylcholine receptors: design, synthesis and FRET investigation C Matera, M Kauk, D Cirillo, M Maspero, C Papotto, D Volpato, ... Molecules 28 (5), 2407, 2023 | 1 | 2023 |
Imidazole Backbone Functionalization with Olefin Cross‐Metathesis F Angelucci, D Cirillo, HR Bjørsvik European Journal of Organic Chemistry 2022 (22), e202200437, 2022 | 1 | 2022 |
A Scalable High‐Yielding and Selective Oxidative Heck Cross‐Coupling – A Key Step for the Synthesis of trans‐Stilbenes D Cirillo, S Karlsson, HR Bjørsvik European Journal of Organic Chemistry 2021 (40), 5519-5529, 2021 | 1 | 2021 |
Therapy HR Bjørsvik, PØ Enger, D Cirillo, S Sarowar US Patent App. 17/763,367, 2022 | | 2022 |
Styrylbenzoic acid derivative DC10 potentiates radiotherapy by inhibiting glutathione synthesis, leading to increased oxidative stress and cancer cell death S Sarowar, D Cirillo, P Jativa, MH Nilsen, SMA Otragane, JI Heggdal, ... Cancer Research 82 (12_Supplement), 214-214, 2022 | | 2022 |
Front Cover: Structure‐Activity‐Relationship‐Aided Design and Synthesis of xCT Antiporter Inhibitors (ChemMedChem 17/2021) D Cirillo, S Sarowar, P Øyvind Enger, HR Bjørsvik ChemMedChem 16 (17), 2546-2546, 2021 | | 2021 |
Tacrine/Xanomeline hybrid ligands: synthesis and pharmacological evaluation at M1 muscarinic acetylcholine receptors and acetylcholinesterases M Maspero, D Volpato, D Cirillo, U Holzgrabe, M De Amici, C Dallanoce | | 2018 |
Synthesis of a group of novel Xanomeline/77-LH-28-1 hybrid ligands and their FRET investigation at muscarinic acetylcholine receptor subtypes D Cirillo, M Kauk, C Matera, D Volpato, U Holzgrabe, M De Amici, ... Congresso Nazionale della Società Chimica Italiana: atti. 4: divisione di …, 2017 | | 2017 |