DNA sensing by the cGAS–STING pathway in health and disease M Motwani, S Pesiridis, KA Fitzgerald Nature Reviews Genetics 20 (11), 657-674, 2019 | 1013 | 2019 |
Nrf2 negatively regulates STING indicating a link between antiviral sensing and metabolic reprogramming D Olagnier, AM Brandtoft, C Gunderstofte, NL Villadsen, C Krapp, ... Nature communications 9 (1), 3506, 2018 | 227 | 2018 |
Nitro-fatty acids are formed in response to virus infection and are potent inhibitors of STING palmitoylation and signaling AL Hansen, GJ Buchan, M Rühl, K Mukai, SR Salvatore, E Ogawa, ... Proceedings of the National Academy of Sciences 115 (33), E7768-E7775, 2018 | 193 | 2018 |
Hierarchy of clinical manifestations in SAVI N153S and V154M mouse models M Motwani, S Pawaria, J Bernier, S Moses, K Henry, T Fang, L Burkly, ... Proceedings of the National Academy of Sciences 116 (16), 7941-7950, 2019 | 99 | 2019 |
Genetic models reveal cis and trans immune-regulatory activities for lincRNA-Cox2 R Elling, EK Robinson, B Shapleigh, SC Liapis, S Covarrubias, ... Cell reports 25 (6), 1511-1524. e6, 2018 | 88 | 2018 |
Synergistic inhibition of hepatocellular carcinoma growth by cotargeting chromatin modifying enzymes and poly (ADP‐ribose) polymerases JX Zhang, DQ Li, AR He, M Motwani, V Vasiliou, J Eswaran, L Mishra, ... Hepatology 55 (6), 1840-1851, 2012 | 46 | 2012 |
cGAS-STING pathway does not promote autoimmunity in murine models of SLE M Motwani, J McGowan, J Antonovitch, KMJ Gao, Z Jiang, S Sharma, ... Frontiers in Immunology 12, 605930, 2021 | 41 | 2021 |
Proteome-wide analysis of single-nucleotide variations in the N-glycosylation sequon of human genes R Mazumder, KS Morampudi, M Motwani, S Vasudevan, R Goldman PloS one 7 (5), e36212, 2012 | 38 | 2012 |
Identification of novel gene targets and functions of p21-activated kinase 1 during DNA damage by gene expression profiling M Motwani, DQ Li, A Horvath, R Kumar PloS one 8 (8), e66585, 2013 | 27 | 2013 |
Modeling the initiation of Ewing sarcoma tumorigenesis in differentiating human embryonic stem cells DJ Gordon, M Motwani, D Pellman Oncogene 35 (24), 3092-3102, 2016 | 25 | 2016 |
cGAS micro-manages genotoxic stress M Motwani, KA Fitzgerald Immunity 47 (4), 616-617, 2017 | 19 | 2017 |
p21-activated Kinase-1 Signaling Regulates Transcription of Tissue Factor and Tissue Factor Pathway Inhibitor*♦ B Sánchez-Solana, M Motwani, DQ Li, J Eswaran, R Kumar Journal of Biological Chemistry 287 (47), 39291-39302, 2012 | 19 | 2012 |
Non-synonymous variations in cancer and their effects on the human proteome: workflow for NGS data biocuration and proteome-wide analysis of TCGA data C Cole, K Krampis, K Karagiannis, JS Almeida, WJ Faison, M Motwani, ... BMC bioinformatics 15, 1-18, 2014 | 18 | 2014 |
Radioresistant cells initiate lymphocyte-dependent lung inflammation and IFNγ-dependent mortality in STING gain-of-function mice KMJ Gao, M Motwani, T Tedder, A Marshak-Rothstein, KA Fitzgerald Proceedings of the National Academy of Sciences 119 (25), e2202327119, 2022 | 15 | 2022 |
Proteome‐wide analysis of nonsynonymous single‐nucleotide variations in active sites of human proteins H Dingerdissen, M Motwani, K Karagiannis, V Simonyan, R Mazumder The FEBS journal 280 (6), 1542-1562, 2013 | 15 | 2013 |
Quantifying and mitigating motor phenotypes induced by antisense oligonucleotides in the central nervous system MP Moazami, JM Rembetsy-Brown, F Wang, PM Krishnamurthy, A Weiss, ... BioRxiv, 2021.02. 14.431096, 2021 | 12 | 2021 |
Quantifying and Mitigating Motor Phenotypes Induced by Antisense Oligonucleotides in the Central Nervous System [preprint] MP Moazami, JM Rembetsy-Brown, F Wang, PM Krishnamurthy, A Weiss, ... | | 2021 |
STING Gain-of-Function in Radio-resistant Cells Supports a Lymphocyte Dependent Auto-inflammatory Lung Disease K Gao, M Motwani, A Marshak-Rothstein, K Fitzgerald ARTHRITIS & RHEUMATOLOGY 72, 2020 | | 2020 |
IFNγ Contributes to Splenic B and T cell Activation and Cytopenia in STING Gain-of-Function Autoinflammation KMJ Gao, M Motwani, A Marshak-Rothstein, KA Fitzgerald The Journal of Immunology 204 (1_Supplement), 224.34-224.34, 2020 | | 2020 |
Cytosolic DNA sensing in autoimmune and autoinflammatory diseases M Motwani | | 2020 |