Global profiling of lysine reactivity and ligandability in the human proteome SM Hacker, KM Backus, MR Lazear, S Forli, BE Correia, BF Cravatt Nature chemistry 9 (12), 1181-1190, 2017 | 388 | 2017 |
An activity-guided map of electrophile-cysteine interactions in primary human T cells EV Vinogradova, X Zhang, D Remillard, DC Lazar, RM Suciu, Y Wang, ... Cell 182 (4), 1009-1026. e29, 2020 | 227 | 2020 |
A proteome-wide atlas of lysine-reactive chemistry ME Abbasov, ME Kavanagh, TA Ichu, MR Lazear, Y Tao, VM Crowley, ... Nature chemistry 13 (11), 1081-1092, 2021 | 131 | 2021 |
Proteome-wide map of targets of T790M-EGFR-directed covalent inhibitors S Niessen, MM Dix, S Barbas, ZE Potter, S Lu, O Brodsky, S Planken, ... Cell chemical biology 24 (11), 1388-1400. e7, 2017 | 89 | 2017 |
Investigation of a substrate-specifying residue within Papaver somniferum and Catharanthus roseus aromatic amino acid decarboxylases MP Torrens-Spence, M Lazear, R von Guggenberg, H Ding, J Li Phytochemistry 106, 37-43, 2014 | 47 | 2014 |
Proteomic discovery of chemical probes that perturb protein complexes in human cells MR Lazear, JR Remsberg, MG Jaeger, K Rothamel, H Her, KE DeMeester, ... Molecular cell 83 (10), 1725-1742. e12, 2023 | 36 | 2023 |
Diverse functional evolution of serine decarboxylases: identification of two novel acetaldehyde synthases that uses hydrophobic amino acids as substrates MP Torrens-Spence, R von Guggenberg, M Lazear, H Ding, J Li BMC plant biology 14, 1-10, 2014 | 19 | 2014 |
Sage: an open-source tool for fast proteomics searching and quantification at scale MR Lazear Journal of Proteome Research 22 (11), 3652-3659, 2023 | 17 | 2023 |
Function-First Proteomic Strategies for Chemical Probe Discovery in Human Cells MR Lazear The Scripps Research Institute, 2022 | | 2022 |