Modifiers of C9orf72 dipeptide repeat toxicity connect nucleocytoplasmic transport defects to FTD/ALS A Jovičić, J Mertens, S Boeynaems, E Bogaert, N Chai, SB Yamada, ... Nature neuroscience 18 (9), 1226-1229, 2015 | 639 | 2015 |
CRISPR–Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity NJ Kramer, MS Haney, DW Morgens, A Jovičić, J Couthouis, A Li, J Ousey, ... Nature genetics 50 (4), 603-612, 2018 | 223 | 2018 |
Parkinson’s Disease Genes VPS35 and EIF4G1 Interact Genetically and Converge on α-Synuclein N Dhungel, S Eleuteri, L Li, NJ Kramer, JW Chartron, B Spencer, ... Neuron 85 (1), 76-87, 2015 | 195 | 2015 |
LRRK2 modifies α-syn pathology and spread in mouse models and human neurons G Bieri, M Brahic, L Bousset, J Couthouis, NJ Kramer, R Ma, L Nakayama, ... Acta neuropathologica 137, 961-980, 2019 | 182 | 2019 |
Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts NJ Kramer, Y Carlomagno, YJ Zhang, S Almeida, CN Cook, TF Gendron, ... Science 353 (6300), 708-712, 2016 | 134 | 2016 |
Altered lymphopoiesis and immunodeficiency in miR-142 null mice NJ Kramer, WL Wang, EY Reyes, B Kumar, CC Chen, C Ramakrishna, ... Blood 125 (24), 3720-3730, 2015 | 125 | 2015 |
RPS25 is required for efficient RAN translation of C9orf72 and other neurodegenerative disease-associated nucleotide repeats SB Yamada, TF Gendron, T Niccoli, NR Genuth, R Grosely, Y Shi, I Glaria, ... Nature neuroscience 22 (9), 1383-1388, 2019 | 93 | 2019 |
Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD LD Goodman, M Prudencio, NJ Kramer, LF Martinez-Ramirez, ... Nature neuroscience 22 (6), 863-874, 2019 | 68 | 2019 |
A versatile system to record cell-cell interactions R Tang, CW Murray, IL Linde, NJ Kramer, Z Lyu, MK Tsai, LC Chen, H Cai, ... eLife 9, e61080, 2020 | 38 | 2020 |
Mutations in palmitoyl-protein thioesterase 1 alter exocytosis and endocytosis at synapses in Drosophila larvae E Aby, K Gumps, A Roth, S Sigmon, SE Jenkins, JJ Kim, NJ Kramer, ... Fly 7 (4), 267-279, 2013 | 37 | 2013 |
Regulators of mitonuclear balance link mitochondrial metabolism to mtDNA expression NJ Kramer, G Prakash, RS Isaac, K Choquet, I Soto, B Petrova, ... Nature Cell Biology 25 (11), 1575-1589, 2023 | 6 | 2023 |
Raise the Roof: Boosting the Efficacy of a Spinal Muscular Atrophy Therapy NJ Kramer, AD Gitler Neuron 93 (1), 3-5, 2017 | 4 | 2017 |
Control of mammalian hematopoiesis and humoral immune response by microRNA-142 (IRM10P. 617) M Boldin, N Kramer, WL Wang, E Reyes, B Kumar, CC Chen, R Chandran, ... The Journal of Immunology 194 (1_Supplement), 131.15-131.15, 2015 | 2 | 2015 |
C9ORF72 Hexanucleotide Repeat Expansions in Neurodegenerative Diseases NJ Kramer Stanford University, 2019 | | 2019 |
Regrowing axons with alternative splicing NJ Kramer, AD Gitler Elife 5, e18707, 2016 | | 2016 |
Unexpected separation of functions at the level of miR-146a targets regulates immune cell activation and malignant transformation N Magilnick, E Reyes, WL Wang, N Kramer, M Boldin The Journal of Immunology 196 (1_Supplement), 202.21-202.21, 2016 | | 2016 |
MicroRNA-29 regulates DNA methylation by targeting oncogene TET2 J Li, NJ Kramer, N Magilnick, MP Boldin Bulletin of the Southern California Academy of Sciences 113 (2), 146-148, 2014 | | 2014 |
MicroRNA-29 negatively regulates expression of oncogene TET2 J Li, NJ Kramer, N Magilnick, MP Boldin Bulletin of the Southern California Academy of Sciences 113 (2), 126-128, 2014 | | 2014 |