Highly multiplexed imaging of tumor tissues with subcellular resolution by mass cytometry C Giesen*, HAO Wang*, D Schapiro, N Zivanovic, A Jacobs, B Hattendorf, ... Nature methods 11 (4), 417-422 -- *Authors contributed equally, 2014 | 1618 | 2014 |
High-definition spatial transcriptomics for in situ tissue profiling S Vickovic*, G Eraslan*, F Salmén*, J Klughammer*, L Stenbeck*, ... Nature methods 16 (10), 987-990 -- *Authors contributed equally, 2019 | 858 | 2019 |
histoCAT: analysis of cell phenotypes and interactions in multiplex image cytometry data D Schapiro, HW Jackson, S Raghuraman, JR Fischer, VRT Zanotelli, ... Nature methods 14 (9), 873-876, 2017 | 504 | 2017 |
A molecular single-cell lung atlas of lethal COVID-19 JC Melms, J Biermann, H Huang, Y Wang, A Nair, S Tagore, I Katsyv, ... Nature 595 (7865), 114-119, 2021 | 495 | 2021 |
The human tumor atlas network: charting tumor transitions across space and time at single-cell resolution O Rozenblatt-Rosen, A Regev, P Oberdoerffer, T Nawy, A Hupalowska, ... Cell 181 (2), 236-249, 2020 | 393 | 2020 |
Simultaneous multiplexed imaging of mRNA and proteins with subcellular resolution in breast cancer tissue samples by mass cytometry D Schulz, VRT Zanotelli, JR Fischer, D Schapiro, S Engler, XK Lun, ... Cell systems 6 (1), 25-36. e5, 2018 | 270 | 2018 |
Spatial multi-omic map of human myocardial infarction C Kuppe, RO Ramirez Flores, Z Li, S Hayat, RT Levinson, X Liao, ... Nature 608 (7924), 766-777, 2022 | 246 | 2022 |
A map of human type 1 diabetes progression by imaging mass cytometry N Damond, S Engler, VRT Zanotelli, D Schapiro, CH Wasserfall, ... Cell metabolism 29 (3), 755-768. e5, 2019 | 232 | 2019 |
Immunogenomic profiling determines responses to combined PARP and PD-1 inhibition in ovarian cancer A Färkkilä, DC Gulhan, J Casado, CA Jacobson, H Nguyen, ... Nature communications 11 (1), 1459, 2020 | 216 | 2020 |
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment WL Hwang, KA Jagadeesh, JA Guo, HI Hoffman, P Yadollahpour, ... Nature genetics 54 (8), 1178-1191, 2022 | 184* | 2022 |
Modeling cell-cell interactions from spatial molecular data with spatial variance component analysis D Arnol, D Schapiro, B Bodenmiller, J Saez-Rodriguez, O Stegle Cell reports 29 (1), 202-211. e6, 2019 | 150 | 2019 |
MCMICRO: a scalable, modular image-processing pipeline for multiplexed tissue imaging D Schapiro, A Sokolov, C Yapp, YA Chen, JL Muhlich, J Hess, ... Nature methods 19 (3), 311-315, 2022 | 127 | 2022 |
Explainable multiview framework for dissecting spatial relationships from highly multiplexed data J Tanevski, ROR Flores, A Gabor, D Schapiro, J Saez-Rodriguez Genome biology 23 (1), 97, 2022 | 91* | 2022 |
Receptor-driven ERK pulses reconfigure MAPK signaling and enable persistence of drug-adapted BRAF-mutant melanoma cells L Gerosa, C Chidley, F Fröhlich, G Sanchez, SK Lim, J Muhlich, JY Chen, ... Cell systems 11 (5), 478-494. e9, 2020 | 91 | 2020 |
Evolution of delayed resistance to immunotherapy in a melanoma responder D Liu, JR Lin, EJ Robitschek, GG Kasumova, A Heyde, A Shi, A Kraya, ... Nature medicine 27 (6), 985-992, 2021 | 79 | 2021 |
Dissecting the treatment-naive ecosystem of human melanoma brain metastasis J Biermann, JC Melms, AD Amin, Y Wang, LA Caprio, A Karz, S Tagore, ... Cell 185 (14), 2591-2608. e30, 2022 | 69 | 2022 |
Automatic single cell segmentation on highly multiplexed tissue images PJ Schüffler*, D Schapiro*, C Giesen, HAO Wang, B Bodenmiller, ... Cytometry Part A 87 (10), 936-942 -- *Authors contributed equally, 2015 | 62 | 2015 |
Highly multiplexed immunofluorescence images and single-cell data of immune markers in tonsil and lung cancer R Rashid, G Gaglia, YA Chen, JR Lin, Z Du, Z Maliga, D Schapiro, C Yapp, ... Scientific data 6 (1), 323, 2019 | 52 | 2019 |
High-dimensional phenotyping identifies age-emergent cells in human mammary epithelia FAP Vatter, D Schapiro, H Chang, AD Borowsky, JK Lee, B Parvin, ... Cell reports 23 (4), 1205-1219, 2018 | 50 | 2018 |
Influence of node abundance on signaling network state and dynamics analyzed by mass cytometry XK Lun, VRT Zanotelli, JD Wade, D Schapiro, M Tognetti, N Dobberstein, ... Nature biotechnology 35 (2), 164-172, 2017 | 48 | 2017 |