| Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia AP Weng, AA Ferrando, W Lee, JP Morris IV, LB Silverman, ... Science 306 (5694), 269-271, 2004 | 3355 | 2004 |
| Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning MA Shipp, KN Ross, P Tamayo, AP Weng, JL Kutok, RCT Aguiar, ... Nature medicine 8 (1), 68-74, 2002 | 3168 | 2002 |
| c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma AP Weng, JM Millholland, Y Yashiro-Ohtani, ML Arcangeli, A Lau, C Wai, ... Genes & development 20 (15), 2096-2109, 2006 | 1076 | 2006 |
| NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth T Palomero, WK Lim, DT Odom, ML Sulis, PJ Real, A Margolin, ... Proceedings of the National Academy of Sciences 103 (48), 18261-18266, 2006 | 1031 | 2006 |
| Targeting transcription regulation in cancer with a covalent CDK7 inhibitor N Kwiatkowski, T Zhang, PB Rahl, BJ Abraham, J Reddy, SB Ficarro, ... Nature 511 (7511), 616-620, 2014 | 845 | 2014 |
| Critical assessment of automated flow cytometry data analysis techniques N Aghaeepour, G Finak, FlowCAP Consortium, Dream Consortium, ... Nature methods 10 (3), 228-238, 2013 | 670 | 2013 |
| The International Human Epigenome Consortium: a blueprint for scientific collaboration and discovery HG Stunnenberg, S Abrignani, D Adams, M de Almeida, L Altucci, V Amin, ... Cell 167 (5), 1145-1149, 2016 | 522 | 2016 |
| Growth suppression of pre-T acute lymphoblastic leukemia cells by inhibition of notch signaling AP Weng, Y Nam, MS Wolfe, WS Pear, JD Griffin, SC Blacklow, JC Aster Molecular and cellular biology, 2003 | 510 | 2003 |
| Whole transcriptome sequencing reveals recurrent NOTCH1 mutations in mantle cell lymphoma R Kridel, B Meissner, S Rogic, M Boyle, A Telenius, B Woolcock, ... Blood, The Journal of the American Society of Hematology 119 (9), 1963-1971, 2012 | 415 | 2012 |
| Mastermind critically regulates Notch-mediated lymphoid cell fate decisions I Maillard, AP Weng, AC Carpenter, CG Rodriguez, H Sai, L Xu, D Allman, ... Blood 104 (6), 1696-1702, 2004 | 364 | 2004 |
| The public repository of xenografts enables discovery and randomized phase II-like trials in mice EC Townsend, MA Murakami, A Christodoulou, AL Christie, J Köster, ... Cancer cell 29 (4), 574-586, 2016 | 332 | 2016 |
| Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia SM Chan, AP Weng, R Tibshirani, JC Aster, PJ Utz Blood, The Journal of the American Society of Hematology 110 (1), 278-286, 2007 | 321 | 2007 |
| Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1 DJ Izon, JC Aster, Y He, A Weng, FG Karnell, V Patriub, L Xu, S Bakkour, ... Immunity 16 (2), 231-243, 2002 | 315 | 2002 |
| Multiple niches for Notch in cancer: context is everything AP Weng, JC Aster Current opinion in genetics & development 14 (1), 48-54, 2004 | 307 | 2004 |
| Notch subunit heterodimerization and prevention of ligand-independent proteolytic activation depend, respectively, on a novel domain and the LNR repeats C Sanchez-Irizarry, AC Carpenter, AP Weng, WS Pear, JC Aster, ... Molecular and cellular biology, 2004 | 304 | 2004 |
| Probabilistic cell-type assignment of single-cell RNA-seq for tumor microenvironment profiling AW Zhang, C O’Flanagan, EA Chavez, JLP Lim, N Ceglia, A McPherson, ... Nature methods 16 (10), 1007-1015, 2019 | 281 | 2019 |
| Structural requirements for assembly of the CSL· intracellular Notch1· Mastermind-like 1 transcriptional activation complex Y Nam, AP Weng, JC Aster, SC Blacklow Journal of Biological Chemistry 278 (23), 21232-21239, 2003 | 278 | 2003 |
| Phenothiazines induce PP2A-mediated apoptosis in T cell acute lymphoblastic leukemia A Gutierrez, L Pan, RWJ Groen, F Baleydier, A Kentsis, J Marineau, ... The Journal of clinical investigation 124 (2), 644-655, 2014 | 237 | 2014 |
| Comprehensive microRNA expression profiling of the hematopoietic hierarchy OI Petriv, F Kuchenbauer, AD Delaney, V Lecault, A White, D Kent, ... Proceedings of the National Academy of Sciences 107 (35), 15443-15448, 2010 | 202 | 2010 |
| High-level IGF1R expression is required for leukemia-initiating cell activity in T-ALL and is supported by Notch signaling H Medyouf, S Gusscott, H Wang, JC Tseng, C Wai, O Nemirovsky, ... Journal of Experimental Medicine 208 (9), 1809-1822, 2011 | 193 | 2011 |
