Mitochondrial glutathione: recent insights and role in disease M Marí, E de Gregorio, C de Dios, V Roca-Agujetas, B Cucarull, ... Antioxidants 9 (10), 909, 2020 | 132 | 2020 |
Gas6/Axl pathway is activated in chronic liver disease and its targeting reduces fibrosis via hepatic stellate cell inactivation C Bárcena, M Stefanovic, A Tutusaus, L Joannas, A Menéndez, ... Journal of hepatology 63 (3), 670-678, 2015 | 128 | 2015 |
Antiapoptotic BCL-2 proteins determine sorafenib/regorafenib resistance and BH3-mimetic efficacy in hepatocellular carcinoma A Tutusaus, M Stefanovic, L Boix, B Cucarull, A Zamora, L Blasco, ... Oncotarget 9 (24), 16701, 2018 | 65 | 2018 |
Angiogenin secretion from hepatoma cells activates hepatic stellate cells to amplify a self-sustained cycle promoting liver cancer C Bárcena, M Stefanovic, A Tutusaus, GA Martinez-Nieto, L Martinez, ... Scientific reports 5 (1), 7916, 2015 | 60 | 2015 |
Cysteine cathepsins control hepatic NF-κB-dependent inflammation via sirtuin-1 regulation Á De Mingo, E De Gregorio, A Moles, N Tarrats, A Tutusaus, A Colell, ... Cell Death & Disease 7 (11), e2464-e2464, 2016 | 59 | 2016 |
Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma M Stefanovic, A Tutusaus, GA Martinez-Nieto, C Bárcena, E de Gregorio, ... Oncotarget 7 (7), 8253, 2016 | 53 | 2016 |
Hepatocellular carcinoma: molecular pathogenesis and therapeutic advances B Cucarull, A Tutusaus, P Rider, T Hernáez-Alsina, C Cuño, ... Cancers 14 (3), 621, 2022 | 51 | 2022 |
A functional role of GAS6/TAM in nonalcoholic steatohepatitis progression implicates AXL as therapeutic target A Tutusaus, E de Gregorio, B Cucarull, H Cristóbal, C Aresté, I Graupera, ... Cellular and molecular gastroenterology and hepatology 9 (3), 349-368, 2020 | 51 | 2020 |
Neurogenin3 cooperates with Foxa2 to autoactivate its own expression M Ejarque, S Cervantes, G Pujadas, A Tutusaus, L Sanchez, R Gasa Journal of Biological Chemistry 288 (17), 11705-11717, 2013 | 51 | 2013 |
Role of vitamin K-dependent factors protein S and GAS6 and TAM receptors in SARS-CoV-2 infection and COVID-19-associated immunothrombosis A Tutusaus, M Marí, JT Ortiz-Pérez, GAF Nicolaes, A Morales, ... Cells 9 (10), 2186, 2020 | 47 | 2020 |
Growth arrest-specific factor 6 (GAS6) is increased in COVID-19 patients and predicts clinical outcome A Morales, S Rojo Rello, H Cristóbal, A Fiz-López, E Arribas, M Marí, ... Biomedicines 9 (4), 335, 2021 | 26 | 2021 |
Regorafenib alteration of the BCL-xL/MCL-1 ratio provides a therapeutic opportunity for BH3-mimetics in hepatocellular carcinoma models B Cucarull, A Tutusaus, M Subías, M Stefanovic, T Hernáez-Alsina, L Boix, ... Cancers 12 (2), 332, 2020 | 23 | 2020 |
Antioxidants threaten multikinase inhibitor efficacy against liver cancer by blocking mitochondrial reactive oxygen species B Cucarull, A Tutusaus, T Hernáez-Alsina, P Garcia de Frutos, M Reig, ... Antioxidants 10 (9), 1336, 2021 | 17 | 2021 |
Genetic and clinical data reinforce the role of GAS6 and TAM receptors in liver fibrosis M Marí, A Tutusaus, PG de Frutos, A Morales Journal of Hepatology 64 (4), 983-984, 2016 | 9 | 2016 |
Wnt9a deficiency discloses a repressive role of Tcf7l2 on endocrine differentiation in the embryonic pancreas G Pujadas, S Cervantes, A Tutusaus, M Ejarque, L Sanchez, A García, ... Scientific Reports 6 (1), 1-15, 2016 | 9 | 2016 |
Sex-based differences in natural killer T cell-mediated protection against diet-induced steatohepatitis in Balb/c mice C Cuño-Gómiz, E de Gregorio, A Tutusaus, P Rider, N Andrés-Sánchez, ... Biology of sex Differences 14 (1), 85, 2023 | 5 | 2023 |
Targeting glucosylceramide synthase upregulation reverts sorafenib resistance in experimental hepatocellular carcinoma. Oncotarget. 2016; 7: 8253–8267 M Stefanovic, A Tutusaus, GA Martinez-Nieto, C Bárcena, E de Gregorio, ... | 5 | |
Sorafenib/Regorafenib resistance and BH3-mimetics efficacy in hepatocellular carcinoma treatment is determined by mitochondrial changes in the BCL-2 profile A Tutusaus, M Stefanovic, B Cucarull, M Mari, L Boix, M Reig, J Bruix, ... Journal of hepatology 68, S686-S687, 2018 | 3 | 2018 |
Growth Arrest-Specific Factor 6 (GAS6) Is Increased in COVID-19 Patients and Predicts Clinical Outcome. Biomedicines 2021, 9, 335 A Morales, S Rojo Rello, H Cristóbal, A Fiz-López, E Arribas, M Marí, ... s Note: MDPI stays neutral with regard to jurisdictional claims in published …, 2021 | 2 | 2021 |
Targeting mitochondrial function with the BCL-2 inhibitor ABT-263 increases therapy efficacy and evades sorafenib resistance A Morales, A Tutusaus, JC Fernández-Checa, M Marí, M Stefanovic | 2 | 2016 |