Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia S Degryse, CE De Bock, S Demeyer, I Govaerts, S Bornschein, D Verbeke, ... Leukemia 32 (3), 788-800, 2018 | 85 | 2018 |
Single-cell DNA amplicon sequencing reveals clonal heterogeneity and evolution in T-cell acute lymphoblastic leukemia L Albertí-Servera, S Demeyer, I Govaerts, T Swings, J De Bie, O Gielen, ... Blood, The Journal of the American Society of Hematology 137 (6), 801-811, 2021 | 55 | 2021 |
JAK/STAT pathway mutations in T-ALL, including the STAT5B N642H mutation, are sensitive to JAK1/JAK3 inhibitors I Govaerts, K Jacobs, R Vandepoel, J Cools HemaSphere 3 (6), e313, 2019 | 18 | 2019 |
PSEN1-selective gamma-secretase inhibition in combination with kinase or XPO-1 inhibitors effectively targets T cell acute lymphoblastic leukemia I Govaerts, C Prieto, C Vandersmissen, O Gielen, K Jacobs, S Provost, ... Journal of Hematology & Oncology 14 (1), 97, 2021 | 11 | 2021 |
Identification of novel targets for treatment in T-cell acute lymphoblastic leukemia I Govaerts | | 2023 |
P348: MRK-560 AND DEXAMETHASONE ARE SYNERGISTIC IN THE TREATMENT OF T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA C Vandersmissen, CP Fernàndez, O Gielen, K Jacobs, I Govaerts, ... HemaSphere 6, 248-249, 2022 | | 2022 |
Evolution of Clinically Relevant Subclones during Chemotherapy Treatment of ALL As Determined By Single-Cell DNA and RNA Sequencing LA Servera, S Demeyer, I Govaerts, O Gielen, H Segers, A Uyttebroeck, ... Blood 134, 2749, 2019 | | 2019 |
PF159 COMBINATION OF SELECTIVE GAMMA-SECRETASE INHIBITOR MRK-560 WITH OTHER TARGETED THERAPY IS AN EFFECTIVE AND SAFE TREATMENT FOR T-ALL I Govaerts, O Gielen, R Habets, C de Bock, K De Keersmaecker, H Segers, ... HemaSphere 3 (S1), 31, 2019 | | 2019 |
Correction: Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia S Degryse, CE de Bock, S Demeyer, I Govaerts, S Bornschein, D Verbeke, ... Leukemia 32 (12), 2731, 2018 | | 2018 |