关注
Kari Johnson
Kari Johnson
National Institute of Neurological Disorders and Stroke
在 nih.gov 的电子邮件经过验证
标题
引用次数
引用次数
年份
Glutamate receptors as therapeutic targets for Parkinson's disease
KA Johnson, PJ Conn, CM Niswender
CNS & Neurological Disorders-Drug Targets (Formerly Current Drug Targets-CNS …, 2009
3172009
Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4
CM Niswender, KA Johnson, CD Weaver, CK Jones, Z Xiang, Q Luo, ...
Molecular pharmacology 74 (5), 1345-1358, 2008
2342008
Parallel, but dissociable, processing in discrete corticostriatal inputs encodes skill learning
DA Kupferschmidt, K Juczewski, G Cui, KA Johnson, DM Lovinger
Neuron 96 (2), 476-489. e5, 2017
1972017
An allosteric potentiator of M4 mAChR modulates hippocampal synaptic transmission
JK Shirey, Z Xiang, D Orton, AE Brady, KA Johnson, R Williams, JE Ayala, ...
Nature Chemical Biology 4 (1), nchembio. 2007.55, 2007
1782007
A novel assay of Gi/o-linked G protein-coupled receptor coupling to potassium channels provides new insights into the pharmacology of the group III metabotropic glutamate receptors
CM Niswender, KA Johnson, Q Luo, JE Ayala, C Kim, PJ Conn, ...
Molecular pharmacology 73 (4), 1213-1224, 2008
1342008
Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS
S Yin, MJ Noetzel, KA Johnson, R Zamorano, N Jalan-Sakrikar, ...
Journal of Neuroscience 34 (1), 79-94, 2014
1322014
Biased mGlu5-positive allosteric modulators provide in vivo efficacy without potentiating mGlu5 modulation of NMDAR currents
JM Rook, Z Xiang, X Lv, A Ghoshal, JW Dickerson, TM Bridges, ...
Neuron 86 (4), 1029-1040, 2015
1312015
Endocannabinoid Actions on Cortical Terminals Orchestrate Local Modulation of Dopamine Release in the Nucleus Accumbens
Y Mateo, KA Johnson, DP Covey, BK Atwood, HL Wang, S Zhang, ...
Neuron 96 (5), 1112-1126. e5, 2017
1102017
Context-dependent pharmacology exhibited by negative allosteric modulators of metabotropic glutamate receptor 7
CM Niswender, KA Johnson, NR Miller, JE Ayala, Q Luo, R Williams, ...
Molecular pharmacology 77 (3), 459-468, 2010
922010
Presynaptic G protein-coupled receptors: gatekeepers of addiction?
KA Johnson, DM Lovinger
Frontiers in cellular neuroscience 10, 264, 2016
552016
Metabotropic glutamate receptor 2 inhibits thalamically-driven glutamate and dopamine release in the dorsal striatum
KA Johnson, Y Mateo, DM Lovinger
Neuropharmacology 117, 114-123, 2017
462017
Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)
R Williams, KA Johnson, PR Gentry, CM Niswender, CD Weaver, ...
Bioorganic & medicinal chemistry letters 19 (17), 4967-4970, 2009
402009
Local modulation by presynaptic receptors controls neuronal communication and behaviour
DM Lovinger, Y Mateo, KA Johnson, SA Engi, M Antonazzo, JF Cheer
Nature Reviews Neuroscience 23 (4), 191-203, 2022
382022
The metabotropic glutamate receptor 8 agonist (S)-3, 4-DCPG reverses motor deficits in prolonged but not acute models of Parkinson's disease
KA Johnson, CK Jones, MN Tantawy, M Bubser, M Marvanova, MS Ansari, ...
Neuropharmacology 66, 187-195, 2013
332013
Activation of group II metabotropic glutamate receptors induces long-term depression of excitatory synaptic transmission in the substantia nigra pars reticulata
KA Johnson, CM Niswender, PJ Conn, Z Xiang
Neuroscience letters 504 (2), 102-106, 2011
322011
Operant self-stimulation of thalamic terminals in the dorsomedial striatum is constrained by metabotropic glutamate receptor 2
KA Johnson, L Voyvodic, GC Loewinger, Y Mateo, DM Lovinger
Neuropsychopharmacology 45 (9), 1454-1462, 2020
192020
Age-dependent impairment of metabotropic glutamate receptor 2-dependent long-term depression in the mouse striatum by chronic ethanol exposure
KA Johnson, DJ Liput, GE Homanics, DM Lovinger
Alcohol 82, 11-21, 2020
162020
Allosteric modulation of metabotropic glutamate receptors in alcohol use disorder: Insights from preclinical investigations
KA Johnson, DM Lovinger
Advances in Pharmacology 88, 193-232, 2020
132020
Impact of isoflurane anesthesia on D2 receptor occupancy by [18F] fallypride measured by microPET with a modified Logan plot
MN Tantawy, TE Peterson, CK Jones, K Johnson, JM Rook, PJ Conn, ...
Synapse 65 (11), 1173-1180, 2011
112011
Active zone proteins RIM1αβ are required for normal corticostriatal transmission and action control
DA Kupferschmidt, SM Augustin, KA Johnson, DM Lovinger
Journal of Neuroscience 39 (8), 1457-1470, 2019
102019
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