VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma J Zhang, T Wu, J Simon, M Takada, R Saito, C Fan, XD Liu, E Jonasch, ... Science 361 (6399), 290-295, 2018 | 145 | 2018 |
EZH2 noncanonically binds cMyc and p300 through a cryptic transactivation domain to mediate gene activation and promote oncogenesis J Wang, X Yu, W Gong, X Liu, KS Park, A Ma, YH Tsai, Y Shen, T Onikubo, ... Nature cell biology 24 (3), 384-399, 2022 | 104 | 2022 |
A selective WDR5 degrader inhibits acute myeloid leukemia in patient-derived mouse models X Yu, D Li, J Kottur, Y Shen, HS Kim, KS Park, YH Tsai, W Gong, J Wang, ... Science translational medicine 13 (613), eabj1578, 2021 | 81 | 2021 |
ZFX mediates non-canonical oncogenic functions of the androgen receptor splice variant 7 in castrate-resistant prostate cancer L Cai, YH Tsai, P Wang, J Wang, D Li, H Fan, Y Zhao, R Bareja, R Lu, ... Molecular cell 72 (2), 341-354. e6, 2018 | 78 | 2018 |
No easy way out for EZH2: its pleiotropic, noncanonical effects on gene regulation and cellular function J Wang, GG Wang International Journal of Molecular Sciences 21 (24), 9501, 2020 | 56 | 2020 |
Genome-wide screening identifies SFMBT1 as an oncogenic driver in cancer with VHL loss X Liu, JM Simon, H Xie, L Hu, J Wang, G Zurlo, C Fan, TS Ptacek, ... Molecular cell 77 (6), 1294-1306. e5, 2020 | 50 | 2020 |
Extensive diversification of MHC in Chinese giant salamanders Andrias davidianus (Anda-MHC) reveals novel splice variants R Zhu, Z Chen, J Wang, X Liao, JF Gui, QY Zhang Developmental & Comparative Immunology 42 (2), 311-322, 2014 | 48 | 2014 |
E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic leukemia WC Pi, J Wang, M Shimada, JW Lin, H Geng, YL Lee, R Lu, D Li, ... Blood, The Journal of the American Society of Hematology 136 (1), 11-23, 2020 | 31 | 2020 |
Evidence for Paralichthys olivaceus IFITM1 antiviral effect by impeding viral entry into target cells R Zhu, J Wang, XY Lei, JF Gui, QY Zhang Fish & shellfish immunology 35 (3), 918-926, 2013 | 30 | 2013 |
Histone H3 proline 16 hydroxylation regulates mammalian gene expression X Liu, J Wang, JA Boyer, W Gong, S Zhao, L Xie, Q Wu, C Zhang, K Jain, ... Nature genetics 54 (11), 1721-1735, 2022 | 28 | 2022 |
Thymus cDNA library survey uncovers novel features of immune molecules in Chinese giant salamander Andrias davidianus R Zhu, ZY Chen, J Wang, JD Yuan, XY Liao, JF Gui, QY Zhang Developmental & Comparative Immunology 46 (2), 413-422, 2014 | 27 | 2014 |
A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3AR882) Demonstrates a Causal Relationship between Its Dominant-Negative Effect and … R Lu, J Wang, Z Ren, J Yin, Y Wang, L Cai, GG Wang Cancer research 79 (14), 3583-3594, 2019 | 21 | 2019 |
A cryptic transactivation domain of EZH2 binds AR and AR’s splice variant, promoting oncogene activation and tumorous transformation J Wang, KS Park, X Yu, W Gong, HS Earp, GG Wang, J Jin, L Cai Nucleic acids research 50 (19), 10929-10946, 2022 | 17 | 2022 |
Mutations in the C-terminal region affect subcellular localization of crucian carp herpesvirus (CaHV) GPCR J Wang, L Gui, ZY Chen, QY Zhang Virus Genes 52, 484-494, 2016 | 14 | 2016 |
Dissecting and targeting noncanonical functions of EZH2 in multiple myeloma via an EZH2 degrader X Yu, J Wang, W Gong, A Ma, Y Shen, C Zhang, X Liu, L Cai, J Liu, ... Oncogene 42 (13), 994-1009, 2023 | 9 | 2023 |
An EZH2-NF-κB regulatory axis drives expression of pro-oncogenic gene signatures in triple negative breast cancer GJ Dardis, J Wang, JM Simon, GG Wang, AS Baldwin Iscience 26 (7), 2023 | 1 | 2023 |