Fibroblast growth factor 15/19 (FGF15/19) protects from diet-induced hepatic steatosis: development of an FGF19-based chimeric molecule to promote fatty liver regeneration G Alvarez-Sola, I Uriarte, MU Latasa, MG Fernandez-Barrena, R Urtasun, ... Gut 66 (10), 1818-1828, 2017 | 150 | 2017 |
Dual targeting of histone methyltransferase G9a and DNA‐methyltransferase 1 for the treatment of experimental hepatocellular carcinoma M Bárcena‐Varela, S Caruso, S Llerena, G Álvarez‐Sola, I Uriarte, ... Hepatology 69 (2), 587-603, 2019 | 100 | 2019 |
Epigenetic mechanisms and metabolic reprogramming in fibrogenesis: dual targeting of G9a and DNMT1 for the inhibition of liver fibrosis M Barcena-Varela, H Paish, L Alvarez, I Uriarte, MU Latasa, E Santamaria, ... Gut 70 (2), 388-400, 2021 | 75 | 2021 |
Novel microenvironment-based classification of intrahepatic cholangiocarcinoma with therapeutic implications MA Martin-Serrano, B Kepecs, M Torres-Martin, ER Bramel, PK Haber, ... Gut 72 (4), 736-748, 2023 | 69 | 2023 |
Cooperation between distinct cancer driver genes underlies intertumor heterogeneity in hepatocellular carcinoma P Molina-Sánchez, MR de Galarreta, MA Yao, KE Lindblad, E Bresnahan, ... Gastroenterology 159 (6), 2203-2220. e14, 2020 | 68 | 2020 |
Epigenetic mechanisms in hepatic stellate cell activation during liver fibrosis and carcinogenesis M Barcena-Varela, L Colyn, MG Fernandez-Barrena International Journal of Molecular Sciences 20 (10), 2507, 2019 | 67 | 2019 |
Splicing events in the control of genome integrity: role of SLU7 and truncated SRSF3 proteins M Jiménez, R Urtasun, M Elizalde, M Azkona, MU Latasa, I Uriarte, ... Nucleic acids research 47 (7), 3450-3466, 2019 | 58 | 2019 |
Bile acids, FGF15/19 and liver regeneration: From mechanisms to clinical applications G Alvarez-Sola, I Uriarte, MU Latasa, M Jimenez, M Barcena-Varela, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1864 (4 …, 2018 | 52 | 2018 |
The epidermal growth factor receptor ligand amphiregulin protects from cholestatic liver injury and regulates bile acids synthesis E Santamaría, CM Rodríguez‐Ortigosa, I Uriarte, MU Latasa, R Urtasun, ... Hepatology 69 (4), 1632-1647, 2019 | 48 | 2019 |
Fibroblast growth factor 15/19 in hepatocarcinogenesis G Alvarez-Sola, I Uriarte, MU Latasa, R Urtasun, M Bárcena-Varela, ... Digestive Diseases 35 (3), 158-165, 2017 | 48 | 2017 |
Dual targeting of G9a and DNA methyltransferase‐1 for the treatment of experimental cholangiocarcinoma L Colyn, M Bárcena‐Varela, G Álvarez‐Sola, MU Latasa, I Uriarte, ... Hepatology 73 (6), 2380-2396, 2021 | 36 | 2021 |
Engineered fibroblast growth factor 19 protects from acetaminophen-induced liver injury and stimulates aged liver regeneration in mice G Alvarez-Sola, I Uriarte, MU Latasa, M Jimenez, M Barcena-Varela, ... Cell Death & Disease 8 (10), e3083-e3083, 2017 | 27 | 2017 |
The endless sources of hepatocellular carcinoma heterogeneity M Barcena-Varela, A Lujambio Cancers 13 (11), 2621, 2021 | 26 | 2021 |
Identification of lptA, lpxE, and lpxO, Three Genes Involved in the Remodeling of Brucella Cell Envelope R Conde-Álvarez, L Palacios-Chaves, Y Gil-Ramírez, M Salvador-Bescós, ... Frontiers in Microbiology 8, 2657, 2018 | 12 | 2018 |
New evidence supporting the biliary bicarbonate umbrella theory MG Fernandez-Barrena, M Barcena-Varela, JM Banales Clinics and research in hepatology and gastroenterology 41 (2), 126-128, 2017 | 7 | 2017 |
The splicing regulator SLU7 is required to preserve DNMT1 protein stability and DNA methylation M Recalde, M Gárate-Rascón, M Elizalde, M Azkona, MU Latasa, ... Nucleic Acids Research 49 (15), 8592-8609, 2021 | 5 | 2021 |
A novel long noncoding RNA finetunes the DNA damage response in hepatocellular carcinoma M Barcena-Varela, A Lujambio Cancer Research 81 (19), 4899-4900, 2021 | 4 | 2021 |
Revealing anti-PD-1 resistance mechanisms in HCC: A path towards novel combination immunotherapies M Bárcena-Varela Journal of Hepatology 77 (1), 9-11, 2022 | 3 | 2022 |
Dissecting Early Relapse in Liver Cancer, One Cell at a Time. M Bárcena-Varela, A Lujambio Hepatology (Baltimore, Md.) 74 (5), 2891-2893, 2021 | 1 | 2021 |
Targeting metalloproteases is a promising strategy to enhance immunotherapy responses by overcoming immune exclusion in hepatocellular carcinoma M Barcena-Varela, P Berraondo Gut 73 (6), 890-891, 2024 | | 2024 |