The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors HC Crawford, BM Fingleton, LA Rudolph-Owen, KJH Goss, B Rubinfeld, ... Oncogene 18 (18), 2883-2891, 1999 | 933 | 1999 |
Wnt/β-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome AI Khramtsov, GF Khramtsova, M Tretiakova, D Huo, OI Olopade, ... The American journal of pathology 176 (6), 2911-2920, 2010 | 618 | 2010 |
Biology of the adenomatous polyposis coli tumor suppressor KH Goss, J Groden Journal of clinical oncology 18 (9), 1967-1979, 2000 | 590 | 2000 |
Enhanced Tumor Formation in Mice Heterozygous for Blm Mutation KH Goss, MA Risinger, JJ Kordich, MM Sanz, JE Straughen, LE Slovek, ... Science 297 (5589), 2051-2053, 2002 | 243 | 2002 |
β-Catenin is required for the tumorigenic behavior of triple-negative breast cancer cells J Xu, JR Prosperi, N Choudhury, OI Olopade, KH Goss PloS one 10 (2), e0117097, 2015 | 235 | 2015 |
EGFR Signals Downregulate Tumor Suppressors miR-143 and miR-145 in Western Diet–Promoted Murine Colon Cancer: Role of G1 Regulators H Zhu, U Dougherty, V Robinson, R Mustafi, J Pekow, S Kupfer, YC Li, ... Molecular cancer research 9 (7), 960-975, 2011 | 148 | 2011 |
A Wnt-ow of opportunity: targeting the Wnt/β-catenin pathway in breast cancer J R Prosperi, K H Goss Current drug targets 11 (9), 1074-1088, 2010 | 136 | 2010 |
Transcriptional Profiles of Intestinal Tumors in ApcMin Mice are Unique from those of Embryonic Intestine and Identify Novel Gene Targets Dysregulated in … T Reichling, KH Goss, DJ Carson, RW Holdcraft, C Ley-Ebert, D Witte, ... Cancer research 65 (1), 166-176, 2005 | 126 | 2005 |
Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/β-catenin signaling BR Shy, CI Wu, GF Khramtsova, JY Zhang, OI Olopade, KH Goss, ... Cell reports 4 (1), 1-9, 2013 | 125 | 2013 |
The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repair G Langland, J Kordich, J Creaney, KH Goss, K Lillard-Wetherell, ... Journal of Biological Chemistry 276 (32), 30031-30035, 2001 | 122 | 2001 |
Differential expression of matrilysin and cyclooxygenase‐2 in intestinal and colorectal neoplasms RL Shattuck‐Brandt, LW Lamps, KJ Heppner Goss, RN DuBois, ... Molecular Carcinogenesis: Published in cooperation with the University of …, 1999 | 122 | 1999 |
Differing effects of endogenous and synthetic inhibitors of metalloproteinases on intestinal tumorigenesis KJ Heppner Goss, PD Brown, LM Matrisian International journal of cancer 78 (5), 629-635, 1998 | 119 | 1998 |
The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB pathway CD Heinen, KH Goss, JR Cornelius, GF Babcock, ES Knudsen, T Kowalik, ... Gastroenterology 123 (3), 751-763, 2002 | 107 | 2002 |
Matrilysin in early stage intestinal tumorigenesis BM Fingleton, KJH Goss, HC Crawford, LM Matrisian Apmis 107 (1‐6), 102-110, 1999 | 103 | 1999 |
Expression of guanylin is downregulated in mouse and human intestinal adenomas KA Steinbrecher, TMF Tuohy, KH Goss, MC Scott, DP Witte, J Groden, ... Biochemical and biophysical research communications 273 (1), 225-230, 2000 | 93 | 2000 |
Attenuated APC alleles produce functional protein from internal translation initiation K Heppner Goss, C Trzepacz, TMF Tuohy, J Groden Proceedings of the National Academy of Sciences 99 (12), 8161-8166, 2002 | 87 | 2002 |
β‐catenin regulates c‐Myc and CDKN1A expression in breast cancer cells J Xu, Y Chen, D Huo, A Khramtsov, G Khramtsova, C Zhang, KH Goss, ... Molecular carcinogenesis 55 (5), 431-439, 2016 | 73 | 2016 |
Exploiting APC function as a novel cancer therapy A C Lesko, K H Goss, J R Prosperi Current drug targets 15 (1), 90-102, 2014 | 64 | 2014 |
The APC tumor suppressor is required for epithelial cell polarization and three-dimensional morphogenesis AC Lesko, KH Goss, FF Yang, A Schwertner, I Hulur, K Onel, JR Prosperi Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (3), 711-723, 2015 | 39 | 2015 |
Targeting the Wnt pathway in cancer KH Goss, M Kahn Springer Science & Business Media, 2011 | 38 | 2011 |