关注
Kathleen Goss
Kathleen Goss
Sr. Scientific Director, American Cancer Society
在 cancer.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors
HC Crawford, BM Fingleton, LA Rudolph-Owen, KJH Goss, B Rubinfeld, ...
Oncogene 18 (18), 2883-2891, 1999
9331999
Wnt/β-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome
AI Khramtsov, GF Khramtsova, M Tretiakova, D Huo, OI Olopade, ...
The American journal of pathology 176 (6), 2911-2920, 2010
6182010
Biology of the adenomatous polyposis coli tumor suppressor
KH Goss, J Groden
Journal of clinical oncology 18 (9), 1967-1979, 2000
5902000
Enhanced Tumor Formation in Mice Heterozygous for Blm Mutation
KH Goss, MA Risinger, JJ Kordich, MM Sanz, JE Straughen, LE Slovek, ...
Science 297 (5589), 2051-2053, 2002
2432002
β-Catenin is required for the tumorigenic behavior of triple-negative breast cancer cells
J Xu, JR Prosperi, N Choudhury, OI Olopade, KH Goss
PloS one 10 (2), e0117097, 2015
2352015
EGFR Signals Downregulate Tumor Suppressors miR-143 and miR-145 in Western Diet–Promoted Murine Colon Cancer: Role of G1 Regulators
H Zhu, U Dougherty, V Robinson, R Mustafi, J Pekow, S Kupfer, YC Li, ...
Molecular cancer research 9 (7), 960-975, 2011
1482011
A Wnt-ow of opportunity: targeting the Wnt/β-catenin pathway in breast cancer
J R Prosperi, K H Goss
Current drug targets 11 (9), 1074-1088, 2010
1362010
Transcriptional Profiles of Intestinal Tumors in ApcMin Mice are Unique from those of Embryonic Intestine and Identify Novel Gene Targets Dysregulated in …
T Reichling, KH Goss, DJ Carson, RW Holdcraft, C Ley-Ebert, D Witte, ...
Cancer research 65 (1), 166-176, 2005
1262005
Regulation of Tcf7l1 DNA binding and protein stability as principal mechanisms of Wnt/β-catenin signaling
BR Shy, CI Wu, GF Khramtsova, JY Zhang, OI Olopade, KH Goss, ...
Cell reports 4 (1), 1-9, 2013
1252013
The Bloom's syndrome protein (BLM) interacts with MLH1 but is not required for DNA mismatch repair
G Langland, J Kordich, J Creaney, KH Goss, K Lillard-Wetherell, ...
Journal of Biological Chemistry 276 (32), 30031-30035, 2001
1222001
Differential expression of matrilysin and cyclooxygenase‐2 in intestinal and colorectal neoplasms
RL Shattuck‐Brandt, LW Lamps, KJ Heppner Goss, RN DuBois, ...
Molecular Carcinogenesis: Published in cooperation with the University of …, 1999
1221999
Differing effects of endogenous and synthetic inhibitors of metalloproteinases on intestinal tumorigenesis
KJ Heppner Goss, PD Brown, LM Matrisian
International journal of cancer 78 (5), 629-635, 1998
1191998
The APC tumor suppressor controls entry into S-phase through its ability to regulate the cyclin D/RB pathway
CD Heinen, KH Goss, JR Cornelius, GF Babcock, ES Knudsen, T Kowalik, ...
Gastroenterology 123 (3), 751-763, 2002
1072002
Matrilysin in early stage intestinal tumorigenesis
BM Fingleton, KJH Goss, HC Crawford, LM Matrisian
Apmis 107 (1‐6), 102-110, 1999
1031999
Expression of guanylin is downregulated in mouse and human intestinal adenomas
KA Steinbrecher, TMF Tuohy, KH Goss, MC Scott, DP Witte, J Groden, ...
Biochemical and biophysical research communications 273 (1), 225-230, 2000
932000
Attenuated APC alleles produce functional protein from internal translation initiation
K Heppner Goss, C Trzepacz, TMF Tuohy, J Groden
Proceedings of the National Academy of Sciences 99 (12), 8161-8166, 2002
872002
β‐catenin regulates c‐Myc and CDKN1A expression in breast cancer cells
J Xu, Y Chen, D Huo, A Khramtsov, G Khramtsova, C Zhang, KH Goss, ...
Molecular carcinogenesis 55 (5), 431-439, 2016
732016
Exploiting APC function as a novel cancer therapy
A C Lesko, K H Goss, J R Prosperi
Current drug targets 15 (1), 90-102, 2014
642014
The APC tumor suppressor is required for epithelial cell polarization and three-dimensional morphogenesis
AC Lesko, KH Goss, FF Yang, A Schwertner, I Hulur, K Onel, JR Prosperi
Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (3), 711-723, 2015
392015
Targeting the Wnt pathway in cancer
KH Goss, M Kahn
Springer Science & Business Media, 2011
382011
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