Widespread FUS mislocalization is a molecular hallmark of amyotrophic lateral sclerosis GE Tyzack, R Luisier, DM Taha, J Neeves, M Modic, JS Mitchell, I Meyer, ... Brain 142 (9), 2572-2580, 2019 | 171 | 2019 |
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS R Luisier, GE Tyzack, CE Hall, JS Mitchell, H Devine, DM Taha, B Malik, ... Nature communications 9 (1), 2010, 2018 | 152 | 2018 |
Distinct responses of neurons and astrocytes to TDP-43 proteinopathy in amyotrophic lateral sclerosis P Smethurst, E Risse, GE Tyzack, JS Mitchell, DM Taha, YR Chen, ... Brain 143 (2), 430-440, 2020 | 91 | 2020 |
Meta-analysis of human and mouse ALS astrocytes reveals multi-omic signatures of inflammatory reactive states OJ Ziff, BE Clarke, DM Taha, H Crerar, NM Luscombe, R Patani Genome research 32 (1), 71-84, 2022 | 62 | 2022 |
Regionally encoded functional heterogeneity of astrocytes in health and disease: A perspective BE Clarke, DM Taha, GE Tyzack, R Patani Glia 69 (1), 20-27, 2021 | 62 | 2021 |
Astrocytes display cell autonomous and diverse early reactive states in familial amyotrophic lateral sclerosis DM Taha, BE Clarke, CE Hall, GE Tyzack, OJ Ziff, L Greensmith, B Kalmar, ... Brain 145 (2), 481-489, 2022 | 33 | 2022 |
Aberrant cytoplasmic intron retention is a blueprint for RNA binding protein mislocalization in VCP-related amyotrophic lateral sclerosis GE Tyzack, J Neeves, H Crerar, P Klein, O Ziff, DM Taha, R Luisier, ... Brain 144 (7), 1985-1993, 2021 | 20 | 2021 |
Reactive astrocytes in ALS display diminished intron retention OJ Ziff, DM Taha, H Crerar, BE Clarke, AM Chakrabarti, G Kelly, J Neeves, ... Nucleic Acids Research 49 (6), 3168-3184, 2021 | 20 | 2021 |
Human stem cell-derived astrocytes exhibit region-specific heterogeneity in their secretory profiles BE Clarke, DM Taha, OJ Ziff, A Alam, EP Thelin, NM García, A Helmy, ... Brain 143 (10), e85-e85, 2020 | 14 | 2020 |
Automated and unbiased discrimination of ALS from control tissue at single cell resolution C Hagemann, GE Tyzack, DM Taha, H Devine, L Greensmith, ... Brain Pathology 31 (4), e12937, 2021 | 10 | 2021 |
Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. Nat Commun 9: 2010 R Luisier, GE Tyzack, CE Hall, JS Mitchell, H Devine, DM Taha, B Malik, ... | 7 | 2018 |
An aberrant cytoplasmic intron retention programme is a blueprint for ALS-related RBP mislocalization GE Tyzack, J Neeves, P Klein, H Crerar, O Ziff, DM Taha, R Luisier, ... bioRxiv, 2020.07. 20.211557, 2020 | 3 | 2020 |
Diversity of early astrocyte reactive profiles in familial amyotrophic lateral sclerosis D Taha, B Clarke, C Hall, G Tyzack, O Ziff, L Greensmith, B Kalmar, ... Brain, 2021 | 2 | 2021 |
Role of TDP-43 in reactive transformation of astrocytes in human stem cell model D Taha, G Manferrari, R Patani GLIA 71, E879-E879, 2023 | | 2023 |
Examining molecular mechanisms underlying reactivity of ALS astrocytes using human stem cell models DMA Taha UCL (University College London), 2022 | | 2022 |
Automated and unbiased classification of motor neuron phenotypes with single cell resolution in ALS tissue C Hagemann, GE Tyzack, DM Taha, H Devine, L Greensmith, ... bioRxiv, 2020.08. 17.253773, 2020 | | 2020 |