Structure of the human multidrug transporter ABCG2 NMI Taylor, I Manolaridis, SM Jackson, J Kowal, H Stahlberg, KP Locher Nature 546 (7659), 504-509, 2017 | 414 | 2017 |
Structural insight into substrate and inhibitor discrimination by human P-glycoprotein A Alam, J Kowal, E Broude, I Roninson, KP Locher Science 363 (6428), 753-756, 2019 | 376 | 2019 |
Structural basis of small-molecule inhibition of human multidrug transporter ABCG2 SM Jackson, I Manolaridis, J Kowal, M Zechner, NMI Taylor, M Bause, ... Nature structural & molecular biology 25 (4), 333-340, 2018 | 306 | 2018 |
Cryo-EM structures of a human ABCG2 mutant trapped in ATP-bound and substrate-bound states I Manolaridis, SM Jackson, NMI Taylor, J Kowal, H Stahlberg, KP Locher Nature 563 (7731), 426-430, 2018 | 228 | 2018 |
Structure of the yeast oligosaccharyltransferase complex gives insight into eukaryotic N-glycosylation R Wild, J Kowal, J Eyring, EM Ngwa, M Aebi, KP Locher Science 359 (6375), 545-550, 2018 | 191 | 2018 |
Structure of a zosuquidar and UIC2-bound human-mouse chimeric ABCB1 A Alam, R Küng, J Kowal, RA McLeod, N Tremp, EV Broude, IB Roninson, ... Proceedings of the National Academy of Sciences 115 (9), E1973-E1982, 2018 | 169 | 2018 |
Cryo-EM structures reveal distinct mechanisms of inhibition of the human multidrug transporter ABCB1 K Nosol, K Romane, RN Irobalieva, A Alam, J Kowal, N Fujita, KP Locher Proceedings of the National Academy of Sciences 117 (42), 26245-26253, 2020 | 166 | 2020 |
Solution structure of discoidal high-density lipoprotein particles with a shortened apolipoprotein AI S Bibow, Y Polyhach, C Eichmann, CN Chi, J Kowal, S Albiez, ... Nature structural & molecular biology 24 (2), 187-193, 2017 | 138 | 2017 |
In situ structural analysis of the Yersinia enterocolitica injectisome M Kudryashev, M Stenta, S Schmelz, M Amstutz, U Wiesand, ... Elife 2, e00792, 2013 | 130 | 2013 |
Cryo–electron microscopy structures of human oligosaccharyltransferase complexes OST-A and OST-B AS Ramírez, J Kowal, KP Locher Science 366 (6471), 1372-1375, 2019 | 101 | 2019 |
Membrane association landscape of myelin basic protein portrays formation of the myelin major dense line A Raasakka, S Ruskamo, J Kowal, R Barker, A Baumann, A Martel, ... Scientific reports 7 (1), 4974, 2017 | 76 | 2017 |
Ligand-induced structural changes in the cyclic nucleotide-modulated potassium channel MloK1 J Kowal, M Chami, P Baumgartner, M Arheit, PL Chiu, M Rangl, ... Nature communications 5 (1), 3106, 2014 | 74 | 2014 |
Structure of the human lipid exporter ABCB4 in a lipid environment JA Olsen, A Alam, J Kowal, B Stieger, KP Locher Nature structural & molecular biology 27 (1), 62-70, 2020 | 71 | 2020 |
Structural basis of drug recognition by the multidrug transporter ABCG2 J Kowal, D Ni, SM Jackson, I Manolaridis, H Stahlberg, KP Locher Journal of molecular biology 433 (13), 166980, 2021 | 65 | 2021 |
Lipid internal dynamics probed in nanodiscs D Martinez, M Decossas, J Kowal, L Frey, H Stahlberg, EJ Dufourc, ... ChemPhysChem 18 (19), 2651-2657, 2017 | 60 | 2017 |
Structures of ABCG2 under turnover conditions reveal a key step in the drug transport mechanism Q Yu, D Ni, J Kowal, I Manolaridis, SM Jackson, H Stahlberg, KP Locher Nature Communications 12 (1), 4376, 2021 | 59 | 2021 |
Preparation and characterization of stable α-synuclein lipoprotein particles C Eichmann, S Campioni, J Kowal, I Maslennikov, J Gerez, X Liu, ... Journal of Biological Chemistry 291 (16), 8516-8527, 2016 | 59 | 2016 |
Molecular structure and function of myelin protein P0 in membrane stacking A Raasakka, S Ruskamo, J Kowal, H Han, A Baumann, M Myllykoski, ... Scientific reports 9 (1), 642, 2019 | 52 | 2019 |
Development of a universal nanobody-binding Fab module for fiducial-assisted cryo-EM studies of membrane proteins JS Bloch, S Mukherjee, J Kowal, EV Filippova, M Niederer, E Pardon, ... Proceedings of the National Academy of Sciences 118 (47), e2115435118, 2021 | 50 | 2021 |
Functional surface engineering by nucleotide-modulated potassium channel insertion into polymer membranes attached to solid supports J Kowal, JK Kowal, D Wu, H Stahlberg, CG Palivan, WP Meier Biomaterials 35 (26), 7286-7294, 2014 | 46 | 2014 |