CRISPR-engineered T cells in patients with refractory cancer EA Stadtmauer*, JA Fraietta*, MM Davis, AD Cohen, KL Weber, ... Science 367 (6481), 2020 | 1180 | 2020 |
Atlas of subcellular RNA localization revealed by APEX-seq FM Fazal*, S Han*, KR Parker, P Kaewsapsak, J Xu, AN Boettiger, ... Cell 178 (2), 473-490. e26, 2019 | 462 | 2019 |
Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling EW Weber, KR Parker, E Sotillo, RC Lynn, H Anbunathan, J Lattin, ... Science 372 (6537), eaba1786, 2021 | 395 | 2021 |
Single-Cell Analyses Identify Brain Mural Cells Expressing CD19 as Potential Off-Tumor Targets for CAR-T Immunotherapies KR Parker, D Migliorini, E Perkey, KE Yost, A Bhaduri, P Bagga, M Haris, ... Cell 183 (1), 126-142. e17, 2020 | 340 | 2020 |
Coupled single-cell CRISPR screening and epigenomic profiling reveals causal gene regulatory networks AJ Rubin*, KR Parker*, AT Satpathy*, Y Qi, B Wu, AJ Ong, MR Mumbach, ... Cell 176 (1-2), 361-376. e17, 2019 | 252 | 2019 |
Discovery and functional interrogation of SARS-CoV-2 RNA-host protein interactions RA Flynn, JA Belk, Y Qi, Y Yasumoto, J Wei, MM Alfajaro, Q Shi, ... Cell 184 (9), 2394-2411. e16, 2021 | 159* | 2021 |
RNA-GPS Predicts SARS-CoV-2 RNA Residency to Host Mitochondria and Nucleolus KE Wu, FM Fazal, KR Parker, J Zou, HY Chang Cell Systems 11 (1), 102-108, 2020 | 139 | 2020 |
Transcript-indexed ATAC-seq for precision immune profiling AT Satpathy*, N Saligrama*, JD Buenrostro, Y Wei, B Wu, AJ Rubin, ... Nature medicine 24 (5), 580-590, 2018 | 126 | 2018 |
Enhanced safety and efficacy of protease-regulated CAR-T cell receptors L Labanieh, RG Majzner, D Klysz, E Sotillo, CJ Fisher, JG Vilches-Moure, ... Cell 185 (10), 1745-1763. e22, 2022 | 117 | 2022 |
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity S Heitzeneder, KR Bosse, Z Zhu, D Zhelev, RG Majzner, MT Radosevich, ... Cancer cell 40 (1), 53-69. e9, 2022 | 97 | 2022 |
ciRS-7 exonic sequence is embedded in a long non-coding RNA locus SP Barrett*, KR Parker*, C Horn, M Mata, J Salzman PLoS genetics 13 (12), e1007114, 2017 | 77 | 2017 |
NOT-gated CD93 CAR T cells effectively target AML with minimized endothelial cross-reactivity RM Richards, F Zhao, KA Freitas, KR Parker, P Xu, A Fan, E Sotillo, ... Blood Cancer Discovery 2 (6), 648-665, 2021 | 53 | 2021 |
Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells CA Tsuchida, N Brandes, R Bueno, M Trinidad, T Mazumder, B Yu, ... Cell 186 (21), 4567-4582. e20, 2023 | 49 | 2023 |
Surface Proteomics Reveals CD72 as a Target for In Vitro–Evolved Nanobody-Based CAR-T Cells in KMT2A/MLL1-Rearranged B-ALL MA Nix, K Mandal, H Geng, N Paranjape, YHT Lin, JM Rivera, ... Cancer discovery 11 (8), 2032-2049, 2021 | 45 | 2021 |
Engineered cell entry links receptor biology with single-cell genomics B Yu, Q Shi, JA Belk, KE Yost, KR Parker, R Li, BB Liu, H Huang, ... Cell 185 (26), 4904-4920. e22, 2022 | 29* | 2022 |
RNA-GPS predicts high-resolution RNA subcellular localization and highlights the role of splicing KE Wu, KR Parker, FM Fazal, HY Chang, J Zou RNA 26 (7), 851-865, 2020 | 14 | 2020 |
RNA-binding proteins direct myogenic cell fate decisions JR Wheeler, ON Whitney, TO Vogler, ED Nguyen, B Pawlikowski, E Lester, ... Elife 11, e75844, 2022 | 13 | 2022 |
CD22 CAR T-cell associated hematologic toxicities, endothelial activation and relationship to neurotoxicity J Jess, B Yates, A Dulau-Florea, K Parker, J Inglefield, D Lichtenstein, ... Journal for Immunotherapy of Cancer 11 (6), 2023 | 12 | 2023 |
Charting the tumor antigen maps drawn by single-cell genomics CA Lareau, KR Parker, AT Satpathy Cancer Cell 39 (12), 1553-1557, 2021 | 10 | 2021 |
APEX-seq: RNA subcellular localization by proximity labeling FM Fazal, S Han, KR Parker, P Kaewsapsak, J Xu, A Boettiger, HY Chang, ... | 3 | 2019 |