| Apolipoprotein E4 inhibits autophagy gene products through direct, specific binding to CLEAR motifs PA Parcon, M Balasubramaniam, S Ayyadevara, RA Jones, L Liu, ... Alzheimer's & Dementia 14 (2), 230-242, 2018 | 90 | 2018 |
| Proteins in aggregates functionally impact multiple neurodegenerative disease models by forming proteasome‐blocking complexes S Ayyadevara, M Balasubramaniam, Y Gao, LR Yu, R Alla, ... Aging Cell 14 (1), 35-48, 2015 | 67 | 2015 |
| Proteins that mediate protein aggregation and cytotoxicity distinguish Alzheimer's hippocampus from normal controls S Ayyadevara, M Balasubramaniam, PA Parcon, SW Barger, WST Griffin, ... Aging cell 15 (5), 924-939, 2016 | 61 | 2016 |
| Structural insights of metallo-beta-lactamase revealed an effective way of inhibition of enzyme by natural inhibitors BS Gangadharappa, R Sharath, PD Revanasiddappa, V Chandramohan, ... Journal of Biomolecular Structure and Dynamics 38 (13), 3757-3771, 2020 | 53 | 2020 |
| Aspirin-mediated acetylation protects against multiple neurodegenerative pathologies by impeding protein aggregation S Ayyadevara, M Balasubramaniam, S Kakraba, R Alla, JL Mehta, ... Antioxidants & redox signaling 27 (17), 1383-1396, 2017 | 52 | 2017 |
| Proteins that accumulate with age in human skeletal-muscle aggregates contribute to declines in muscle mass and function in Caenorhabditis elegans S Ayyadevara, M Balasubramaniam, P Suri, SG Mackintosh, AJ Tackett, ... Aging (Albany NY) 8 (12), 3486, 2016 | 51 | 2016 |
| Computational target-based drug repurposing of elbasvir, an antiviral drug predicted to bind multiple SARS-CoV-2 proteins M Balasubramaniam, RJS Reis ChemRxiv, 2020 | 46 | 2020 |
| MMB triazole analogs are potent NF-κB inhibitors and anti-cancer agents against both hematological and solid tumor cells V Janganati, J Ponder, M Balasubramaniam, P Bhat-Nakshatri, EE Bar, ... European journal of medicinal chemistry 157, 562-581, 2018 | 38 | 2018 |
| A novel tetrazole analogue of resveratrol is a potent anticancer agent S Bommagani, NR Penthala, M Balasubramaniam, S Kuravi, ... Bioorganic & medicinal chemistry letters 29 (2), 172-178, 2019 | 33 | 2019 |
| Biological evaluation of 2-arylidene-4, 7-dimethyl indan-1-one (FXY-1): a novel Akt inhibitor with potent activity in lung cancer P Rajagopalan, KA Alahmari, AA Elbessoumy, M Balasubramaniam, ... Cancer chemotherapy and pharmacology 77, 393-404, 2016 | 31 | 2016 |
| Structural modeling of GSK3β implicates the inactive (DFG-out) conformation as the target bound by TDZD analogs M Balasubramaniam, N Mainali, SK Bowroju, P Atluri, NR Penthala, ... Scientific reports 10 (1), 18326, 2020 | 26 | 2020 |
| Intrinsically disordered proteins identified in the aggregate proteome serve as biomarkers of neurodegeneration S Ayyadevara, A Ganne, M Balasubramaniam, RJ Shmookler Reis Metabolic Brain Disease 37 (1), 147-152, 2022 | 24 | 2022 |
| ALS-causing mutations in profilin-1 alter its conformational dynamics: A computational approach to explain propensity for aggregation M Kiaei, M Balasubramaniam, V Govind Kumar, RJ Shmookler Reis, ... Scientific reports 8 (1), 13102, 2018 | 22 | 2018 |
| Interleukin-1β drives NEDD8 nuclear-to-cytoplasmic translocation, fostering parkin activation via NEDD8 binding to the P-ubiquitin activating site M Balasubramaniam, PA Parcon, C Bose, L Liu, RA Jones, MR Farlow, ... Journal of Neuroinflammation 16, 1-17, 2019 | 21 | 2019 |
| Structural insights into pro-aggregation effects of C. elegans CRAM-1 and its human ortholog SERF2 M Balasubramaniam, S Ayyadevara, RJ Shmookler Reis Scientific Reports 8 (1), 14891, 2018 | 20 | 2018 |
| “Protein aggregates” contain RNA and DNA, entrapped by misfolded proteins but largely rescued by slowing translational elongation RJ Shmookler Reis, R Atluri, M Balasubramaniam, J Johnson, A Ganne, ... Aging Cell 20 (5), e13326, 2021 | 19 | 2021 |
| FCX‐146, a potent allosteric inhibitor of Akt kinase in cancer cells: lead optimization of the second‐generation arylidene indanone scaffold M Balasubramaniam, NR Lakkaniga, AA Dera, MA Fayi, M Abohashrh, ... Biotechnology and Applied Biochemistry 68 (1), 82-91, 2021 | 19 | 2021 |
| Structural characterization of the aurora kinase B “DFG-flip” using metadynamics NR Lakkaniga, M Balasubramaniam, S Zhang, B Frett, H Li The AAPS journal 22, 1-9, 2020 | 19 | 2020 |
| Glial fibrillary acidic protein: a biomarker and drug target for alzheimer’s disease A Ganne, M Balasubramaniam, WST Griffin, RJ Shmookler Reis, ... Pharmaceutics 14 (7), 1354, 2022 | 17 | 2022 |
| A novel microtubule-binding drug attenuates and reverses protein aggregation in animal models of Alzheimer’s Disease S Kakraba, S Ayyadevara, NR Penthala, M Balasubramaniam, A Ganne, ... Frontiers in Molecular Neuroscience 12, 310, 2019 | 16 | 2019 |
