| Whole-genome multiple displacement amplification from single cells C Spits, C Le Caignec, M De Rycke, L Van Haute, A Van Steirteghem, ... Nature protocols 1 (4), 1965-1970, 2006 | 341 | 2006 |
| Recurrent chromosomal abnormalities in human embryonic stem cells C Spits, I Mateizel, M Geens, A Mertzanidou, C Staessen, Y Vandeskelde, ... Nature biotechnology 26 (12), 1361-1363, 2008 | 312 | 2008 |
| Single-cell chromosomal imbalances detection by array CGH C Le Caignec, C Spits, K Sermon, M De Rycke, B Thienpont, S Debrock, ... Nucleic acids research 34 (9), e68-e68, 2006 | 268 | 2006 |
| Optimization and evaluation of single‐cell whole‐genome multiple displacement amplification C Spits, C Le Caignec, M De Rycke, L Van Haute, A Van Steirteghem, ... Human Mutation 27 (5), 496-503, 2006 | 259 | 2006 |
| Microarray analysis reveals abnormal chromosomal complements in over 70% of 14 normally developing human embryos A Mertzanidou, L Wilton, J Cheng, C Spits, E Vanneste, Y Moreau, ... Human reproduction 28 (1), 256-264, 2013 | 236 | 2013 |
| Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage Nature biotechnology 29 (12), 1132-1144, 2011 | 144 | 2011 |
| Gain of 20q11. 21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL HT Nguyen, M Geens, A Mertzanidou, K Jacobs, C Heirman, K Breckpot, ... Molecular human reproduction 20 (2), 168-177, 2014 | 131 | 2014 |
| Recent developments in genetics and medically-assisted reproduction: from research to clinical applications JC Harper, K Aittomäki, P Borry, MC Cornel, G De Wert, W Dondorp, ... Human reproduction open 2017 (3), hox015, 2017 | 122 | 2017 |
| Human embryonic stem cell lines derived from single blastomeres of two 4-cell stage embryos M Geens, I Mateizel, K Sermon, M De Rycke, C Spits, G Cauffman, ... Human reproduction 24 (11), 2709-2717, 2009 | 122 | 2009 |
| Genetic and epigenetic instability in human pluripotent stem cells HT Nguyen, M Geens, C Spits Human reproduction update 19 (2), 187-205, 2013 | 112 | 2013 |
| CpG methylation, a parent-of-origin effect for maternal-biased transmission of congenital myotonic dystrophy L Barbé, S Lanni, A López-Castel, S Franck, C Spits, K Keymolen, ... The American Journal of Human Genetics 100 (3), 488-505, 2017 | 104 | 2017 |
| Huntington's and myotonic dystrophy hESCs: down-regulated trinucleotide repeat instability and mismatch repair machinery expression upon differentiation A Seriola, C Spits, JP Simard, P Hilven, P Haentjens, CE Pearson, ... Human molecular genetics 20 (1), 176-185, 2011 | 101 | 2011 |
| Higher-density culture in human embryonic stem cells results in DNA damage and genome instability K Jacobs, F Zambelli, A Mertzanidou, I Smolders, M Geens, HT Nguyen, ... Stem Cell Reports 6 (3), 330-341, 2016 | 100 | 2016 |
| PGD for monogenic disorders: aspects of molecular biology C Spits, K Sermon Prenatal Diagnosis: Published in Affiliation With the International Society …, 2009 | 79 | 2009 |
| Current issues in medically assisted reproduction and genetics in Europe: research, clinical practice, ethics, legal issues and policy J Harper, J Geraedts, P Borry, MC Cornel, WJ Dondorp, L Gianaroli, ... Human Reproduction 29 (8), 1603-1609, 2014 | 78 | 2014 |
| Preimplantation genetic diagnosis for cancer predisposition syndromes C Spits, M De Rycke, N Van Ranst, W Verpoest, W Lissens, ... Prenatal Diagnosis: Published in Affiliation With the International Society …, 2007 | 69 | 2007 |
| Evolution of aneuploidy up to Day 4 of human preimplantation development A Mertzanidou, C Spits, HT Nguyen, H Van de Velde, K Sermon Human Reproduction 28 (6), 1716-1724, 2013 | 68 | 2013 |
| Current issues in medically assisted reproduction and genetics in Europe: research, clinical practice, ethics, legal issues and policy JC Harper, J Geraedts, P Borry, MC Cornel, W Dondorp, L Gianaroli, ... European Journal of Human Genetics 21 (2), S1-S21, 2013 | 60 | 2013 |
| Genetic and epigenetic factors which modulate differentiation propensity in human pluripotent stem cells A Keller, D Dziedzicka, F Zambelli, C Markouli, K Sermon, C Spits, ... Human Reproduction Update 24 (2), 162-175, 2018 | 59 | 2018 |
| Preimplantation genetic diagnosis for neurofibromatosis type 1 C Spits, M De Rycke, N Van Ranst, H Joris, W Verpoest, W Lissens, ... Molecular human reproduction 11 (5), 381-387, 2005 | 58 | 2005 |
