A Pro12Ala substitution in PPARγ2 associated with decreased receptor activity, lower body mass index and improved insulin sensitivity SS Deeb, L Fajas, M Nemoto, J Pihlajamäki, L Mykkänen, J Kuusisto, ... Nature genetics 20 (3), 284-287, 1998 | 1862 | 1998 |
The MBOAT7-TMC4 variant rs641738 increases risk of nonalcoholic fatty liver disease in individuals of European descent RM Mancina, P Dongiovanni, S Petta, P Pingitore, M Meroni, R Rametta, ... Gastroenterology 150 (5), 1219-1230. e6, 2016 | 650 | 2016 |
Probiotics modulated gut microbiota suppresses hepatocellular carcinoma growth in mice J Li, CYJ Sung, N Lee, Y Ni, J Pihlajamäki, G Panagiotou, H El-Nezami Proceedings of the National Academy of Sciences 113 (9), E1306-E1315, 2016 | 597 | 2016 |
Transmembrane 6 superfamily member 2 gene variant disentangles nonalcoholic steatohepatitis from cardiovascular disease P Dongiovanni, S Petta, C Maglio, AL Fracanzani, R Pipitone, E Mozzi, ... Hepatology 61 (2), 506-514, 2015 | 572 | 2015 |
Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome U Salmenniemi, E Ruotsalainen, J Pihlajamäki, I Vauhkonen, ... Circulation 110 (25), 3842-3848, 2004 | 385 | 2004 |
Two polymorphisms in the peroxisome proliferator-activated receptor-γ gene are associated with severe overweight among obese women R Valve, K Sivenius, R Miettinen, J Pihlajamaki, A Rissanen, SS Deeb, ... The Journal of Clinical Endocrinology & Metabolism 84 (10), 3708-3712, 1999 | 337 | 1999 |
Linkage of familial combined hyperlipidaemia to chromosome 1q21–q23 P Pajukanta, I Nuotio, JD Terwilliger, KVK Porkka, K Ylitalo, J Pihlajamäki, ... Nature genetics 18 (4), 369-373, 1998 | 323 | 1998 |
Promoter polymorphisms of the TNF-α (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: the Finnish Diabetes Prevention … A Kubaszek, J Pihlajamaki, V Komarovski, V Lindi, J Lindstrom, J Eriksson, ... Diabetes 52 (7), 1872-1876, 2003 | 305 | 2003 |
Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study VD de Mello, J Paananen, J Lindström, MA Lankinen, L Shi, J Kuusisto, ... Scientific reports 7 (1), 46337, 2017 | 296 | 2017 |
Hyperglycemia and a common variant of GCKR are associated with the levels of eight amino acids in 9,369 Finnish men A Stančáková, M Civelek, NK Saleem, P Soininen, AJ Kangas, ... Diabetes 61 (7), 1895-1902, 2012 | 292 | 2012 |
Insulin resistance is associated with increased cholesterol synthesis and decreased cholesterol absorption in normoglycemic men J Pihlajamäki, H Gylling, TA Miettinen, M Laakso Journal of lipid research 45 (3), 507-512, 2004 | 239 | 2004 |
Epigenetic alterations in human liver from subjects with type 2 diabetes in parallel with reduced folate levels E Nilsson, A Matte, A Perfilyev, VD de Mello, P Käkelä, J Pihlajamäki, ... The Journal of Clinical Endocrinology & Metabolism 100 (11), E1491-E1501, 2015 | 205 | 2015 |
The C-174G promoter polymorphism of the IL-6 gene affects energy expenditure and insulin sensitivity A Kubaszek, J Pihlajamäki, K Punnonen, P Karhapää, I Vauhkonen, ... Diabetes 52 (2), 558-561, 2003 | 200 | 2003 |
Genomewide scan for familial combined hyperlipidemia genes in Finnish families, suggesting multiple susceptibility loci influencing triglyceride, cholesterol, and … P Pajukanta, JD Terwilliger, M Perola, T Hiekkalinna, I Nuotio, P Ellonen, ... The American Journal of Human Genetics 64 (5), 1453-1463, 1999 | 200 | 1999 |
Diverse associations of 25‐hydroxyvitamin D and 1, 25‐dihydroxy‐vitamin D with dyslipidaemias P Karhapää, J Pihlajamäki, I Pörsti, M Kastarinen, J Mustonen, O Niemelä, ... Journal of internal medicine 268 (6), 604-610, 2010 | 199 | 2010 |
Associations of serum indolepropionic acid, a gut microbiota metabolite, with type 2 diabetes and low-grade inflammation in high-risk individuals M Tuomainen, J Lindström, M Lehtonen, S Auriola, J Pihlajamäki, ... Nutrition & diabetes 8 (1), 35, 2018 | 190 | 2018 |
DNA methylation of loci within ABCG1 and PHOSPHO1 in blood DNA is associated with future type 2 diabetes risk T Dayeh, T Tuomi, P Almgren, A Perfilyev, PA Jansson, VD de Mello, ... Epigenetics 11 (7), 482-488, 2016 | 187 | 2016 |
Polymorphisms in the ABCG5 and ABCG8 genes associate with cholesterol absorption and insulin sensitivity H Gylling, M Hallikainen, J Pihlajamäki, J Ågren, M Laakso, ... Journal of lipid research 45 (9), 1660-1665, 2004 | 182 | 2004 |
PKCδ regulates hepatic insulin sensitivity and hepatosteatosis in mice and humans O Bezy, TT Tran, J Pihlajamäki, R Suzuki, B Emanuelli, J Winnay, MA Mori, ... The Journal of clinical investigation 121 (6), 2504-2517, 2011 | 174 | 2011 |
Conjugated bile acids associate with altered rates of glucose and lipid oxidation after Roux-en-Y gastric bypass M Simonen, N Dali-Youcef, D Kaminska, S Venesmaa, P Käkelä, ... Obesity surgery 22, 1473-1480, 2012 | 169 | 2012 |