DNA methylation-based classification of central nervous system tumours D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ... Nature 555 (7697), 469-474, 2018 | 2313 | 2018 |
Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups KW Pajtler, H Witt, M Sill, DTW Jones, V Hovestadt, F Kratochwil, K Wani, ... Cancer cell 27 (5), 728-743, 2015 | 1105 | 2015 |
New brain tumor entities emerge from molecular classification of CNS-PNETs D Sturm, BA Orr, UH Toprak, V Hovestadt, DTW Jones, D Capper, M Sill, ... Cell 164 (5), 1060-1072, 2016 | 838 | 2016 |
Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma DTW Jones, B Hutter, N Jäger, A Korshunov, M Kool, HJ Warnatz, ... Nature genetics 45 (8), 927-932, 2013 | 817 | 2013 |
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ... Nature genetics 46 (5), 451-456, 2014 | 630 | 2014 |
Glioblastoma multiforme: State of the art and future therapeutics TA Wilson, MA Karajannis, DH Harter Surgical neurology international 5, 2014 | 420 | 2014 |
Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis V Ramaswamy, M Remke, E Bouffet, CC Faria, S Perreault, YJ Cho, ... The lancet oncology 14 (12), 1200-1207, 2013 | 405 | 2013 |
Pediatric high-grade glioma: biologically and clinically in need of new thinking C Jones, MA Karajannis, DTW Jones, MW Kieran, M Monje, SJ Baker, ... Neuro-oncology 19 (2), 153-161, 2017 | 376 | 2017 |
Integrated molecular and clinical analysis of 1,000 pediatric low-grade gliomas S Ryall, M Zapotocky, K Fukuoka, L Nobre, AG Stucklin, J Bennett, ... Cancer cell 37 (4), 569-583. e5, 2020 | 328 | 2020 |
Therapeutic and prognostic implications of BRAF V600E in pediatric low-grade gliomas A Lassaletta, M Zapotocky, M Mistry, V Ramaswamy, M Honnorat, ... Journal of Clinical Oncology 35 (25), 2934-2941, 2017 | 308 | 2017 |
Merlin/NF2 loss-driven tumorigenesis linked to CRL4DCAF1-mediated inhibition of the Hippo pathway kinases Lats1 and 2 in the nucleus W Li, J Cooper, L Zhou, C Yang, H Erdjument-Bromage, D Zagzag, ... Cancer cell 26 (1), 48-60, 2014 | 251 | 2014 |
Pediatric brain tumors: innovative genomic information is transforming the diagnostic and clinical landscape A Gajjar, DC Bowers, MA Karajannis, S Leary, H Witt, NG Gottardo Journal of Clinical Oncology 33 (27), 2986-2998, 2015 | 242 | 2015 |
Oncolytic HSV-1 G207 immunovirotherapy for pediatric high-grade gliomas GK Friedman, JM Johnston, AK Bag, JD Bernstock, R Li, I Aban, ... New England Journal of Medicine 384 (17), 1613-1622, 2021 | 234 | 2021 |
Phase II study of sorafenib in children with recurrent or progressive low-grade astrocytomas MA Karajannis, G Legault, MJ Fisher, SS Milla, KJ Cohen, JH Wisoff, ... Neuro-oncology 16 (10), 1408-1416, 2014 | 215 | 2014 |
Polymorphous low-grade neuroepithelial tumor of the young (PLNTY): an epileptogenic neoplasm with oligodendroglioma-like components, aberrant CD34 expression, and genetic … JT Huse, M Snuderl, DTW Jones, CD Brathwaite, N Altman, E Lavi, ... Acta neuropathologica 133, 417-429, 2017 | 214 | 2017 |
Infant high-grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes M Clarke, A Mackay, B Ismer, JC Pickles, RG Tatevossian, S Newman, ... Cancer discovery 10 (7), 942-963, 2020 | 213 | 2020 |
Immunohistochemical analysis of H3K27me3 demonstrates global reduction in group-A childhood posterior fossa ependymoma and is a powerful predictor of outcome P Panwalkar, J Clark, V Ramaswamy, D Hawes, F Yang, C Dunham, ... Acta neuropathologica 134, 705-714, 2017 | 205 | 2017 |
Phase II trial of lapatinib in adult and pediatric patients with neurofibromatosis type 2 and progressive vestibular schwannomas MA Karajannis, G Legault, M Hagiwara, MS Ballas, K Brown, ... Neuro-oncology 14 (9), 1163-1170, 2012 | 195 | 2012 |
Therapeutic impact of cytoreductive surgery and irradiation of posterior fossa ependymoma in the molecular era: a retrospective multicohort analysis V Ramaswamy, T Hielscher, SC Mack, A Lassaletta, T Lin, KW Pajtler, ... Journal of clinical oncology 34 (21), 2468-2477, 2016 | 193 | 2016 |
Recurrent MET fusion genes represent a drug target in pediatric glioblastoma Nature medicine 22 (11), 1314-1320, 2016 | 185 | 2016 |