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Rowena Martin
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年份
Functional profiling of a Plasmodium genome reveals an abundance of essential genes
E Bushell, AR Gomes, T Sanderson, B Anar, G Girling, C Herd, T Metcalf, ...
Cell 170 (2), 260-272. e8, 2017
5102017
Chloroquine transport via the malaria parasite’s chloroquine resistance transporter
RE Martin, RV Marchetti, AI Cowan, SM Howitt, S Bröer, K Kirk
science 325 (5948), 1680-1682, 2009
4092009
Defining the role of PfCRT in Plasmodium falciparum chloroquine resistance
PG Bray, RE Martin, L Tilley, SA Ward, K Kirk, DA Fidock
Molecular microbiology 56 (2), 323-333, 2005
2942005
The malaria parasite's chloroquine resistance transporter is a member of the drug/metabolite transporter superfamily
RE Martin, K Kirk
Molecular biology and evolution 21 (10), 1938-1949, 2004
2832004
Globally prevalent PfMDR1 mutations modulate Plasmodium falciparum susceptibility to artemisinin-based combination therapies
MI Veiga, SK Dhingra, PP Henrich, J Straimer, N Gnädig, AC Uhlemann, ...
Nature communications 7 (1), 11553, 2016
2682016
The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum
RE Martin, RI Henry, JL Abbey, JD Clements, K Kirk
Genome biology 6, 1-22, 2005
2142005
Transport of the essential nutrient isoleucine in human erythrocytes infected with the malaria parasite Plasmodium falciparum
RE Martin, K Kirk
Blood 109 (5), 2217-2224, 2007
1562007
Sodium-dependent uptake of inorganic phosphate by the intracellular malaria parasite
KJ Saliba, RE Martin, A Bröer, RI Henry, C Siobhan McCarthy, MJ Downie, ...
Nature 443 (7111), 582-585, 2006
1192006
Membrane transport proteins of the malaria parasite
RE Martin, H Ginsburg, K Kirk
Molecular microbiology 74 (3), 519-528, 2009
1042009
Know your enemy: understanding the role of PfCRT in drug resistance could lead to new antimalarial tactics
RL Summers, MN Nash, RE Martin
Cellular and Molecular Life Sciences 69, 1967-1995, 2012
962012
Mutations in the Plasmodium falciparum chloroquine resistance transporter, PfCRT, enlarge the parasite’s food vacuole and alter drug sensitivities
S Pulcini, HM Staines, AH Lee, SH Shafik, G Bouyer, CM Moore, ...
Scientific reports 5 (1), 14552, 2015
932015
Diverse mutational pathways converge on saturable chloroquine transport via the malaria parasite’s chloroquine resistance transporter
RL Summers, A Dave, TJ Dolstra, S Bellanca, RV Marchetti, MN Nash, ...
Proceedings of the National Academy of Sciences 111 (17), E1759-E1767, 2014
782014
A lactate and formate transporter in the intraerythrocytic malaria parasite, Plasmodium falciparum
RV Marchetti, AM Lehane, SH Shafik, M Winterberg, RE Martin, K Kirk
Nature communications 6 (1), 6721, 2015
772015
Quinoline antimalarials containing a dibemethin group are active against chloroquinone-resistant Plasmodium falciparum and inhibit chloroquine transport via the P. falciparum …
VK Zishiri, MC Joshi, R Hunter, K Chibale, PJ Smith, RL Summers, ...
Journal of medicinal chemistry 54 (19), 6956-6968, 2011
772011
Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents
S Gemma, C Camodeca, M Brindisi, S Brogi, G Kukreja, S Kunjir, ...
Journal of medicinal chemistry 55 (23), 10387-10404, 2012
722012
The natural function of the malaria parasite’s chloroquine resistance transporter
SH Shafik, SA Cobbold, K Barkat, SN Richards, NS Lancaster, M Llinás, ...
Nature communications 11 (1), 3922, 2020
702020
The malaria parasite's lactate transporter PfFNT is the target of antiplasmodial compounds identified in whole cell phenotypic screens
SV Hapuarachchi, SA Cobbold, SH Shafik, ASM Dennis, MJ McConville, ...
PLoS pathogens 13 (2), e1006180, 2017
532017
Optimization of 4-aminoquinoline/clotrimazole-based hybrid antimalarials: Further structure–activity relationships, in vivo studies, and preliminary toxicity profiling
S Gemma, C Camodeca, S Sanna Coccone, BP Joshi, M Bernetti, ...
Journal of medicinal chemistry 55 (15), 6948-6967, 2012
522012
Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites
S Bellanca, RL Summers, M Meyrath, A Dave, MN Nash, M Dittmer, ...
Journal of Biological Chemistry 289 (52), 36336-36351, 2014
492014
The transportome of the malaria parasite
RE Martin
Biological Reviews 95 (2), 305-332, 2020
482020
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