Neuropharmacology of emesis induced by anti-cancer therapy PLR Andrews, WG Rapeport, GJ Sanger Trends in Pharmacological Sciences 9 (9), 334-341, 1988 | 472 | 1988 |
Safety, tolerability and viral kinetics during SARS-CoV-2 human challenge in young adults B Killingley, AJ Mann, M Kalinova, A Boyers, N Goonawardane, J Zhou, ... Nature Medicine 28 (5), 1031-1041, 2022 | 440 | 2022 |
Combining fMRI with a pharmacokinetic model to determine which brain areas activated by painful stimulation are specifically modulated by remifentanil RG Wise, R Rogers, D Painter, S Bantick, A Ploghaus, P Williams, ... Neuroimage 16 (4), 999-1014, 2002 | 212 | 2002 |
Clinical pharmacokinetics of allopurinol GAC Murrell, WG Rapeport Clinical pharmacokinetics 11 (5), 343-353, 1986 | 169 | 1986 |
A pharmacokinetic study of granisetron (BRL 43694A), a selective 5-HT3 receptor antagonist: correlation with anti-emetic response J Carmichael, BMJ Cantwell, CM Edwards, BD Zussman, S Thompson, ... Cancer chemotherapy and pharmacology 24, 45-49, 1989 | 168 | 1989 |
The influence of diet upon liver function tests and serum lipids in healthy male volunteers resident in a Phase I unit L Purkins, ER Love, MD Eve, CL Wooldridge, C Cowan, TS Smart, ... British journal of clinical pharmacology 57 (2), 199-208, 2004 | 129 | 2004 |
Enzyme-induction dependent bioactivation of troglitazone and troglitazone quinone in vivo JN Tettey, JL Maggs, WG Rapeport, M Pirmohamed, BK Park Chemical research in toxicology 14 (8), 965-974, 2001 | 123 | 2001 |
Reduced nasal viral load and IFN responses in infants with respiratory syncytial virus bronchiolitis and respiratory failure RS Thwaites, M Coates, K Ito, M Ghazaly, C Feather, F Abdulla, T Tunstall, ... American journal of respiratory and critical care medicine 198 (8), 1074-1084, 2018 | 101 | 2018 |
Changes in circulating thyroid hormones during short-term hepatic enzyme induction with carbamazepine JMC Connell, WG Rapeport, S Gordon, MJ Brodie European journal of clinical pharmacology 26, 453-456, 1984 | 94 | 1984 |
Changes in circulating androgens during short term carbamazepine therapy. JM Connell, WG Rapeport, GH Beastall, MJ Brodie British journal of clinical pharmacology 17 (3), 347-351, 1984 | 81 | 1984 |
Carbamazepine 10, 11 epoxide concentrations in epileptics on carbamazepine alone and in combination with other anticonvulsants. MJ Brodie, G Forrest, WG Rapeport British journal of clinical pharmacology 16 (6), 747-749, 1983 | 81 | 1983 |
In Vitro and In Vivo Antifungal Profile of a Novel and Long-Acting Inhaled Azole, PC945, on Aspergillus fumigatus Infection T Colley, A Alanio, SL Kelly, G Sehra, Y Kizawa, AGS Warrilow, JE Parker, ... Antimicrobial agents and chemotherapy 61 (5), 10.1128/aac. 02280-16, 2017 | 72 | 2017 |
Absence of a sertraline-mediated effect on the pharmacokinetics and pharmacodynamics of carbamazepine. WG Rapeport, SA Williams, DC Muirhead, PM Dewland, T Tanner, ... The Journal of clinical psychiatry 57, 20-23, 1996 | 70 | 1996 |
Current approaches to the discovery of novel inhaled medicines P Strong, K Ito, J Murray, G Rapeport Drug discovery today 23 (10), 1705-1717, 2018 | 69 | 2018 |
Pharmacokinetics and anti-emetic efficacy of BRL43694, a new selective 5HT-3 antagonist J Cassidy, V Raina, C Lewis, L Adams, M Soukop, WG Rapeport, ... British journal of cancer 58 (5), 651-653, 1988 | 68 | 1988 |
The serotonin type 3 receptor antagonist BRL 43694 and nausea and vomiting induced by cisplatin. J Carmichael, BM Cantwell, CM Edwards, WG Rapeport, AL Harris BMJ: British Medical Journal 297 (6641), 110, 1988 | 62 | 1988 |
p38 MAP kinase inhibitors K Ito, P Strong, WG Rapeport, J King-Underwood, JG Williams, ST Onions, ... US Patent 8,293,771, 2012 | 54 | 2012 |
SARS-CoV-2 human challenge studies—establishing the model during an evolving pandemic G Rapeport, E Smith, A Gilbert, A Catchpole, H McShane, C Chiu New England Journal of Medicine 385 (11), 961-964, 2021 | 51 | 2021 |
p38 MAP kinase inhibitors K Ito, P Strong, WG Rapeport, PJ Murray, J King-Underwood, JG Williams, ... US Patent 8,293,748, 2012 | 51 | 2012 |
Preclinical characterization of PC786, an inhaled small-molecule respiratory syncytial virus L protein polymerase inhibitor M Coates, D Brookes, YI Kim, H Allen, EAF Fordyce, EA Meals, T Colley, ... Antimicrobial Agents and Chemotherapy 61 (9), 10.1128/aac. 00737-17, 2017 | 50 | 2017 |