The AP-2 family of transcription factors D Eckert, S Buhl, S Weber, R Jäger, H Schorle Genome biology 6 (13), 246, 2005 | 505 | 2005 |
Stress management at the ER: regulators of ER stress-induced apoptosis AM Gorman, SJM Healy, R Jäger, A Samali Pharmacology & therapeutics 134 (3), 306-316, 2012 | 428 | 2012 |
Apoptosis in the terminal endbud of the murine mammary gland: a mechanism of ductal morphogenesis RC Humphreys, M Krajewska, S Krnacik, R Jæger, H Weiher, S Krajewski, ... Development 122 (12), 4013-4022, 1996 | 363 | 1996 |
The human ubiquitin C promoter directs high ubiquitous expression of transgenes in mice M Schorpp, R Jäger, K Schellander, J Schenkel, EF Wagner, H Weiher, ... Nucleic acids research 24 (9), 1787-1788, 1996 | 287 | 1996 |
The unfolded protein response at the crossroads of cellular life and death during endoplasmic reticulum stress R Jäger, MJM Bertrand, AM Gorman, P Vandenabeele, A Samali Biology of the Cell 104 (5), 259-270, 2012 | 256 | 2012 |
Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy SE Logue, EP McGrath, P Cleary, S Greene, K Mnich, A Almanza, ... Nature communications 9 (1), 3267, 2018 | 237 | 2018 |
Overexpression of Bcl-2 inhibits alveolar cell apoptosis during involution and accelerates c-myc-induced tumorigenesis of the mammary gland in transgenic mice R JaÈger, U Herzer, J Schenkel, H Weiher Oncogene 15 (15), 1787-1795, 1997 | 220 | 1997 |
Cell-specific deletion of glucosylceramide synthase in brain leads to severe neural defects after birth R Jennemann, R Sandhoff, S Wang, E Kiss, N Gretz, C Zuliani, ... Proceedings of the National Academy of Sciences 102 (35), 12459-12464, 2005 | 206 | 2005 |
Endoplasmic reticulum stress and the unfolded protein response: targeting the Achilles heel of multiple myeloma L Vincenz, R Jäger, M O'Dwyer, A Samali Molecular cancer therapeutics 12 (6), 831-843, 2013 | 194 | 2013 |
Regulation of apoptosis by heat shock proteins D Kennedy, R Jäger, DD Mosser, A Samali IUBMB life 66 (5), 327-338, 2014 | 156 | 2014 |
Altered mammary epithelial development, pattern formation and involution in transgenic mice expressing the EphB4 receptor tyrosine kinase N Munarini, R Jäger, S Abderhalden, G Zuercher, V Rohrbach, ... Journal of cell science 115 (1), 25-37, 2002 | 138 | 2002 |
New roles for old enzymes: killer caspases as the engine of cell behavior changes PF Connolly, R Jäger, HO Fearnhead Frontiers in physiology 5, 149, 2014 | 109 | 2014 |
Transcription factor AP‐2γ, a novel marker of gonocytes and seminomatous germ cell tumors K Pauls, R Jäger, S Weber, E Wardelmann, A Koch, R Büttner, H Schorle International journal of cancer 115 (3), 470-477, 2005 | 106 | 2005 |
Gain of Bcl-2 Is More Potent Than Bax Loss in Regulating Mammary Epithelial Cell Survival in Vivo K Schorr, M Li, U Bar-Peled, A Lewis, A Heredia, B Lewis, CM Knudson, ... Cancer research 59 (11), 2541-2545, 1999 | 91 | 1999 |
Transcription factor AP-2γ stimulates proliferation and apoptosis and impairs differentiation in a transgenic model R Jäger, U Werling, S Rimpf, A Jacob, H Schorle Molecular cancer research 1 (12), 921-929, 2003 | 79 | 2003 |
The unfolded protein response in breast cancer EP McGrath, SE Logue, K Mnich, S Deegan, R Jäger, AM Gorman, ... Cancers 10 (10), 344, 2018 | 77 | 2018 |
Establishment and controlled differentiation of neural crest stem cell lines using conditional transgenesis J Maurer, S Fuchs, R Jäger, B Kurz, L Sommer, H Schorle Differentiation 75 (7), 580-591, 2007 | 74 | 2007 |
The enigmatic roles of caspases in tumor development R Jäger, RM Zwacka Cancers 2 (4), 1952-1979, 2010 | 69 | 2010 |
Bcl-2 expression delays mammary tumor development in dimethylbenz (a) anthracene-treated transgenic mice KL Murphy, FS Kittrell, JP Gay, R JaÈger, D Medina, JM Rosen Oncogene 18 (47), 6597-6604, 1999 | 67 | 1999 |
Distinct spatial expression patterns of AP-2alpha and AP-2gamma in non-neoplastic human breast and breast cancer N Friedrichs, R Jäger, E Paggen, C Rudlowski, S Merkelbach-Bruse, ... Modern pathology 18 (3), 431-438, 2005 | 65 | 2005 |