The evolution of powerful yet perilous immune systems AL Graham, EC Schrom, CJE Metcalf Trends in immunology 43 (2), 117-131, 2022 | 20 | 2022 |
Sarcoptic mange severity is associated with reduced genomic variation and evidence of selection in Yellowstone National Park wolves (Canis lupus) AL DeCandia, EC Schrom, EE Brandell, DR Stahler, BM Vonholdt Evolutionary applications 14 (2), 429-445, 2021 | 19 | 2021 |
Quorum sensing via dynamic cytokine signaling comprehensively explains divergent patterns of effector choice among helper T cells EC Schrom, SA Levin, AL Graham PLoS computational biology 16 (7), e1008051, 2020 | 14 | 2020 |
vonHoldt BM (2021) AL DeCandia, EC Schrom, EE Brandell, DR Stahler Sarcoptic mange severity is associated with reduced genomic variation and …, 0 | 14 | |
A CRISPR screen targeting PI3K effectors identifies RASA3 as a negative regulator of LFA-1–mediated adhesion in T cells KH Johansen, DP Golec, B Huang, C Park, JH Thomsen, S Preite, ... Science signaling 15 (743), eabl9169, 2022 | 12 | 2022 |
Understanding immunity in a tissue‐centric context: Combining novel imaging methods and mathematics to extract new insights into function and dysfunction RN Germain, AJ Radtke, N Thakur, EC Schrom, JL Hor, H Ichise, ... Immunological Reviews 306 (1), 8-24, 2022 | 11 | 2022 |
Instructed subsets or agile swarms: how T-helper cells may adaptively counter uncertainty with variability and plasticity EC Schrom, AL Graham Current Opinion in Genetics & Development 47, 75-82, 2017 | 11 | 2017 |
Immune signaling networks: sources of robustness and constrained evolvability during coevolution EC Schrom, JM Prada, AL Graham Molecular biology and evolution 35 (3), 676-687, 2018 | 9 | 2018 |
TCR ligand potency differentially impacts PD-1 inhibitory effects on diverse signaling pathways W Chan, YM Cao, X Zhao, EC Schrom, D Jia, J Song, LV Sibener, S Dong, ... Journal of Experimental Medicine 220 (12), e20231242, 2023 | 5 | 2023 |
Challenges in cybersecurity: Lessons from biological defense systems E Schrom, A Kinzig, S Forrest, AL Graham, SA Levin, CT Bergstrom, ... Mathematical Biosciences 362, 109024, 2023 | 3 | 2023 |
Spatial Patterning Analysis of Cellular Ensembles (SPACE) discovers complex spatial organization at the cell and tissue levels EC Schrom, EF McCaffrey, V Sreejithkumar, AJ Radtke, H Ichise, ... bioRxiv, 2023.12. 08.570837, 2023 | | 2023 |
Spatial Patterning Analysis of Cellular Ensembles (SPACE) enables statistically robust discovery of complex spatial organization at the cell and tissue level EC Schrom, EF McCaffrey, AJ Radtke, E Speranza, L Arakkal, N Thakur, ... bioRxiv, 2023 | | 2023 |
579-D Multiplex imaging of ovarian carcinoma reveals spatial cell interaction patterns predictive of immunotherapy responses K Padhan, JM Lee, E Giudice, E Schrom, A Radtke, N Gupta, D An, ... Journal for ImmunoTherapy of Cancer 11 (Suppl 2), 2023 | | 2023 |
The Structure and Dynamics of Immune Signaling Systems as a Coevolved Strategic Counter Against Parasitic Sabotage EC Schrom II Princeton University, 2020 | | 2020 |