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Kaihua Zhang
Kaihua Zhang
Principal Investigator, Fudan University
在 fudan.edu.cn 的电子邮件经过验证 - 首页
标题
引用次数
引用次数
年份
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
4892020
Structure of the human P2Y12 receptor in complex with an antithrombotic drug
K Zhang, J Zhang, ZG Gao, D Zhang, L Zhu, GW Han, SM Moss, ...
Nature 509 (7498), 115-118, 2014
4032014
Two disparate ligand-binding sites in the human P2Y1 receptor
D Zhang, ZG Gao, K Zhang, E Kiselev, S Crane, J Wang, S Paoletta, C Yi, ...
Nature 520 (7547), 317-321, 2015
3292015
Agonist-bound structure of the human P2Y12 receptor
J Zhang, K Zhang, ZG Gao, S Paoletta, D Zhang, GW Han, T Li, L Ma, ...
Nature 509 (7498), 119-122, 2014
3242014
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
Science 370 (6523), 1473-1479, 2020
3072020
Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking
M Schuller, GJ Correy, S Gahbauer, D Fearon, T Wu, RE Díaz, ID Young, ...
Science advances 7 (16), eabf8711, 2021
852021
Bi-paratopic and multivalent VH domains block ACE2 binding and neutralize SARS-CoV-2
CJ Bracken, SA Lim, P Solomon, NJ Rettko, DP Nguyen, BS Zha, ...
Nature Chemical Biology, 1-9, 2020
712020
Structural snapshots of TRPV1 reveal mechanism of polymodal functionality
K Zhang, D Julius, Y Cheng
Cell 184 (20), 5138-5150. e12, 2021
672021
An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
BioRxiv, 2020
572020
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.
M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, G Jang, ...
Research square, 2021
532021
Fusion protein strategies for cryo-EM study of G protein-coupled receptors
K Zhang, H Wu, N Hoppe, A Manglik, Y Cheng
Nature communications 13 (1), 4366, 2022
122022
Autoantibody mimicry of hormone action at the thyrotropin receptor
B Faust, CB Billesbølle, CM Suomivuori, I Singh, K Zhang, N Hoppe, ...
Nature 609 (7928), 846-853, 2022
102022
Consortium QSB, Walter P, Manglik A
M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ...
Science 370 (6523), 1473, 2020
82020
Autoantibody and hormone activation of the thyrotropin G protein-coupled receptor
B Faust, I Singh, K Zhang, N Hoppe, AFM Pinto, Y Muftuoglu, ...
bioRxiv, 2022.01. 06.475289, 2022
32022
Targeting phosphotyrosine in native proteins with conditional, bispecific antibody traps
XX Zhou, CJ Bracken, K Zhang, J Zhou, Y Mou, L Wang, Y Cheng, ...
Journal of the American Chemical Society 142 (41), 17703-17713, 2020
32020
A step-by-step protocol for capturing conformational snapshots of ligand gated ion channels by single-particle cryo-EM
K Zhang, D Julius, Y Cheng
STAR protocols 3 (4), 101732, 2022
2022
Fusion protein strategies for cryo-EM study of G protein-coupled receptors
K Zhang, H Wu, N Hoppe, A Manglik, Y Cheng
Nature Communications, 2022
2022
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes.(preprint)
M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, GM Jang, ...
2021
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes (preprint)
K Verba, M Gupta, C Azumaya, M Moritz, S Pourmal, A Diallo, G Merz, ...
2021
An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation (preprint)
M Schoof, B Faust, RA Saunders, S Sangwan, VV Rezelj, N Hoppe, ...
2020
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